Uceris in 2026: Is the Shortage Over?

If you've been dealing with ulcerative colitis and relying on Uceris (Budesonide ER), you've probably experienced the frustration of hearing your pharmacy say they can't get it. The question on everyone's mind: Is the Uceris shortage finally over in 2026?

The short answer: it's better, but it's not fully resolved. Here's what you need to know.

Is Uceris Still in Shortage?

The situation with Uceris has improved compared to the worst periods of 2022-2023, but availability remains inconsistent depending on where you live and which formulation you need.

Oral tablets (Budesonide ER 9 mg): Supply has improved modestly since 2024. Most regions have reasonable availability, but some areas still experience intermittent stockouts. Generic Budesonide ER from manufacturers like Teva has helped fill the gap.

Rectal foam (Budesonide 2 mg): This formulation has been hit harder and continues to be listed intermittently on the FDA drug shortage list. If you use the rectal foam, you may still face significant difficulty finding it.

The bottom line: the shortage isn't officially over, but the oral tablet is much more findable than it was two years ago — especially if you're open to the generic version.

Why Has Uceris Been So Hard to Find?

Several factors have contributed to the ongoing availability challenges:

Supply Chain Disruptions

The global pharmaceutical supply chain has faced unprecedented pressure since 2022. Raw material sourcing, manufacturing capacity, and distribution logistics have all been strained. Budesonide products, which require specialized extended-release manufacturing, were particularly affected.

Limited Manufacturer Base

Unlike common generics produced by dozens of manufacturers, Budesonide ER tablets have a relatively small number of suppliers. When one manufacturer has an issue, the impact on overall supply is significant.

Regional Distribution Imbalances

Even when nationwide supply is adequate, distribution isn't perfectly even. Some markets — often rural areas or smaller metro regions — receive less stock than major urban centers. This means your pharmacy in one city might have plenty while another 50 miles away has none.

Insurance and Cost Barriers

High costs (brand Uceris runs $1,400 to $2,330 for 30 tablets) mean many pharmacies don't stock it proactively. They only order it when a patient brings in a prescription, which adds days to the process.

For a deeper dive into all the reasons behind the shortage, see our article on why Uceris is so hard to find.

What Does Uceris Cost in 2026?

Cost continues to be a major concern for patients. Here's where prices stand:

• Brand-name Uceris: $1,400 to $2,330 for 30 tablets (one month's supply) at retail price without insurance
• Generic Budesonide ER with discount card: As low as $194 with GoodRx or SingleCare
• Generic at average retail: $627 for 30 tablets without any discount
• With manufacturer savings card: Copay as low as $30 for commercially insured patients
• Patient assistance programs: Free or $70/month for qualifying uninsured/underinsured patients

If cost is a barrier for you, our detailed guide on how to save money on Uceris walks through every savings option available.

Are There New Options for UC Patients in 2026?

The ulcerative colitis treatment landscape continues to evolve. While Uceris remains an important option, patients and doctors now have more choices than ever:

• Generic Budesonide ER: Now more widely available from multiple manufacturers, giving patients a cheaper and often easier-to-find option.
• Newer biologic therapies: Medications like Stelara (Ustekinumab), Zeposia (Ozanimod), and Rinvoq (Upadacitinib) have expanded the treatment options for moderate to severe UC.
• Biosimilars: More affordable versions of biologic drugs are entering the market, which may help patients who need to step up from Uceris-level therapy.

That said, for patients with mild to moderate UC who respond well to Budesonide, Uceris remains a valuable treatment. The key is being able to access it.

How to Find Uceris in Stock Right Now

Here are the most effective strategies for locating Uceris today:

1. Use Medfinder to check real-time pharmacy availability by zip code
2. Ask for generic Budesonide ER — it's easier to find and costs as low as $194
3. Try independent pharmacies that may have more flexible ordering from multiple wholesalers
4. Consider mail-order through your insurance plan or online pharmacies like Cost Plus Drugs
5. Call pharmacies early in the week when new shipments typically arrive
6. Start refills 7-10 days early to give yourself a buffer

For a complete strategy guide, see our article on how to find Uceris in stock near you.

Final Thoughts

The Uceris shortage of 2022-2023 was one of the most frustrating medication access issues for UC patients. While things have gotten better in 2026, we're not out of the woods yet — especially for the rectal foam formulation.

The most important things you can do:

• Be proactive about refills — don't wait until you're out
• Be flexible — the generic works just as well and is easier to find
• Use tools like Medfinder to check availability before driving to the pharmacy
• Know your alternatives — read up on alternative medications so you're prepared if needed
• Stay in touch with your doctor — your gastroenterologist is your best ally in navigating these challenges

For comprehensive information about Uceris including dosage, side effects, and interactions, visit our guides on what is Uceris and Uceris side effects.