Muro 128 Side Effects: What to Expect and When to Call Your Doctor

Updated:

February 24, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Learn about common and serious Muro 128 side effects, who's most at risk, how to manage discomfort, and when to call your doctor right away.

What You Should Know About Muro 128 Side Effects

If your doctor has prescribed Muro 128 for corneal edema, you probably want to know what to expect when you start using it. Like all medications, Muro 128 can cause side effects — but most of them are mild and temporary.

This guide covers the most common side effects, the rare but serious ones to watch for, and practical tips for making your treatment more comfortable.

What Is Muro 128?

Muro 128 is a hypertonic sodium chloride ophthalmic solution or ointment. It comes in 2% and 5% concentrations and is used to reduce corneal edema — swelling of the cornea, the clear front part of your eye. By drawing excess water out of the cornea through osmosis, Muro 128 helps temporarily clear your vision. For a deeper look at how this medication works, see our guide on Muro 128's mechanism of action.

Common Side Effects

Most people who use Muro 128 experience at least one of these effects, especially when they first start treatment:

  • Burning or stinging. This is the most commonly reported side effect. The hypertonic solution can cause a temporary burning sensation when it contacts the eye. It usually lasts a few seconds to a couple of minutes.
  • Temporary blurred vision. Your vision may be slightly blurry right after applying the drops or ointment. This is more noticeable with the ointment form. Avoid driving or operating machinery until your vision clears.
  • Eye irritation. Some patients notice mild redness or a gritty feeling in the eye after application.
  • Tearing. Your eyes may water more than usual as a natural response to the solution.

These side effects are generally mild and tend to improve as your eyes get used to the medication over the first few days of use.

Serious Side Effects

Serious side effects from Muro 128 are rare, but you should know what to watch for. Contact your doctor right away if you experience any of the following:

  • Severe eye pain that doesn't go away after application
  • Persistent vision changes — if your vision stays blurry or gets worse rather than improving
  • Signs of eye infection — increasing redness, swelling, or discharge from the eye
  • Allergic reaction — rash, itching, swelling (especially of the face, tongue, or throat), or difficulty breathing

If you experience difficulty breathing, swelling of the throat, or any signs of a severe allergic reaction, seek emergency medical attention immediately.

Side Effects in Specific Populations

Pregnant or Breastfeeding Women

Muro 128 is classified as Pregnancy Category C, meaning it should be used during pregnancy only if clearly needed and the benefits outweigh the potential risks. Talk to your doctor if you're pregnant, planning to become pregnant, or breastfeeding.

Children

Safety in children has not been well established. If your child needs Muro 128, it should be used only under close doctor supervision.

Older Adults

There are no specific warnings for elderly patients, but older adults may have more sensitive eyes or slower corneal healing. Your doctor may want to monitor you more closely.

How to Manage Side Effects

Here are some practical tips for reducing discomfort while using Muro 128:

  • Use the ointment at bedtime. If you're prescribed both drops and ointment, using the ointment at night minimizes the impact of blurred vision on your daily activities.
  • Start with the 2% concentration. If the 5% solution is too irritating, ask your doctor about starting with the 2% formulation and working up.
  • Wait between eye medications. If you use other eye drops, wait at least 5-10 minutes between medications to prevent washout and reduce irritation.
  • Store properly. Keep Muro 128 at room temperature and check the expiration date. Using expired or improperly stored product can increase irritation.
  • Don't touch the dropper tip to your eye. This can introduce bacteria and lead to infection.
  • Remove contact lenses. Do not wear contact lenses while using Muro 128.

If side effects are making it hard to stick with your treatment, talk to your doctor before stopping. They may adjust your dosage, switch your formulation, or suggest an alternative treatment.

Final Thoughts

Most Muro 128 side effects are mild — a little burning, some temporary blur — and they tend to get better with continued use. Serious reactions are rare but worth knowing about so you can act quickly if they happen.

If you have questions about your specific situation, your ophthalmologist or optometrist is the best resource. And if you need help finding Muro 128 at a pharmacy near you, MedFinder can help you check stock without calling around.

Does Muro 128 burn when you put it in your eyes?

Yes, temporary burning or stinging is the most common side effect of Muro 128, especially with the 5% concentration. It usually lasts only a few seconds to a couple of minutes and tends to improve over time.

Can Muro 128 cause blurry vision?

Yes, temporary blurred vision can occur right after applying Muro 128, particularly with the ointment form. This is normal and should clear within several minutes for drops or longer for the ointment.

When should I stop using Muro 128 and call my doctor?

Contact your doctor if you experience severe eye pain, persistent vision changes, signs of infection (redness, swelling, discharge), or any allergic reaction symptoms like rash, swelling, or difficulty breathing.

Is Muro 128 safe to use during pregnancy?

Muro 128 is Pregnancy Category C. It should only be used during pregnancy if the potential benefits outweigh the risks. Always discuss with your doctor before using Muro 128 if you are pregnant or planning to become pregnant.

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