Moxifloxacin Shortage Update: What Patients Need to Know in 2026

Moxifloxacin has been on the ASHP (American Society of Health-System Pharmacists) drug shortage list since December 2023. As of December 2025, the shortage remains active for certain manufacturers. If you've had trouble filling your moxifloxacin prescription in the past few months, the shortage is a likely contributing factor — and this guide explains what's happening and what you should do.

Current Shortage Status (Updated 2026)

The ASHP drug shortage bulletin for moxifloxacin tablets was created on December 6, 2023, and most recently updated December 15, 2025. Here's the current manufacturer situation:

Teva Pharmaceuticals: Their 400 mg moxifloxacin tablets (30-count, NDC 00093-7387-56) are the primary shortage product. Teva has not provided a reason for the shortage.

Aurobindo Pharma: Aurobindo has refused to provide availability information to ASHP, making it difficult for pharmacies and patients to plan accordingly.

Major Pharmaceuticals: Has moxifloxacin tablets available — pharmacies that source from Major should be able to fill prescriptions.

Rising Pharmaceuticals: Also has moxifloxacin tablets available — another potential source for pharmacies and patients.

The shortage is not a complete absence from the market — it's a manufacturer-specific issue that creates uneven availability across pharmacy networks. Some pharmacies will have it; others won't. The key is finding the right pharmacy.

Which Moxifloxacin Products Are Affected?

Not all formulations of moxifloxacin are equally affected. Here's a breakdown by product type:

Oral tablets (400 mg): Most affected. Specific Teva NDC numbers are listed on the ASHP shortage bulletin. Check if your pharmacy can source from Major or Rising.

IV solution (400 mg/250 mL): Intermittent hospital availability issues; primarily affects inpatient hospital pharmacy operations.

Ophthalmic solution (0.5% — Vigamox, Moxeza, generics): Generally not affected by the current shortage; both generic and brand-name eye drops remain available at most pharmacies.

Why Is There a Moxifloxacin Shortage?

The underlying causes of generic drug shortages in the United States typically involve a combination of manufacturing issues, regulatory hurdles, and thin profit margins. For moxifloxacin specifically:

Concentrated manufacturing. A large proportion of generic pharmaceutical active ingredients are manufactured overseas (primarily in India and China). Disruptions at a single API (active pharmaceutical ingredient) supplier can affect multiple finished-drug manufacturers simultaneously.

Low-margin product. Generic moxifloxacin is inexpensive. Low margins reduce manufacturers' incentives to invest in additional capacity or quickly resolve supply disruptions.

Brand discontinuation. Bayer discontinued brand-name Avelox, leaving the market entirely dependent on generic manufacturers. With fewer total suppliers, any disruption has a bigger impact.

How Long Will the Shortage Last?

Drug shortage timelines are difficult to predict. The ASHP bulletin has been active for over two years as of this writing, with no resolved status announced. The fact that multiple manufacturers (Major, Rising) have supply suggests the shortage may not worsen significantly, but full market normalization depends on Teva and Aurobindo resolving their respective supply situations.

For patients who need moxifloxacin now, the practical reality is that it can still be found — just not at every pharmacy. The shortage makes finding it harder, not impossible.

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What Should Patients Do Right Now?

Don't assume your first pharmacy is your only option. Check multiple pharmacies, especially independent pharmacies that may source from different manufacturers.

Use medfinder. medfinder contacts pharmacies near you to check real-time availability of your exact medication, so you don't have to make a dozen calls yourself.

Ask about manufacturer alternatives. Tell your pharmacist you know Major and Rising have supply. Ask if they can order from one of those manufacturers.

Talk to your doctor if moxifloxacin is truly unavailable. Levofloxacin, azithromycin, and doxycycline are common alternatives depending on your infection type.

For a full step-by-step guide: How to Find Moxifloxacin in Stock Near You (Tools + Tips)

The Bottom Line

The moxifloxacin shortage is real, has been ongoing since December 2023, and continues to affect Teva's product line into 2026. However, the drug is not unavailable — it can be found from Major Pharmaceuticals and Rising Pharmaceuticals. The challenge is pharmacy-level access. With the right tools and information, most patients can still get their moxifloxacin prescription filled — or work with their doctor to find an appropriate alternative.