How to Save Money on Releuko in 2026: Coupons, Discounts, and Patient Assistance

Releuko (filgrastim-ayow) is a specialty oncology biosimilar, and its cost reflects that status. The wholesale acquisition cost (WAC) is approximately $2,280 per syringe or vial at full list price. The average retail price runs around $625 per injection — and that's before the realities of insurance formularies, prior authorization, and specialty pharmacy mark-ups. If you're managing these costs out of pocket or facing high copays, here is a comprehensive breakdown of every savings tool available to you in 2026.

What Does Releuko Cost Without Insurance?

The real-world cash cost of Releuko depends on the dose and where you fill it:

Average retail price (no discount): ~$625 per injection (either strength)

With GoodRx coupon: As low as $489.87 (22% off average retail price as of April 2026)

Drugs.com discount price for 300 mcg/0.5 mL: From $179.74

Drugs.com discount price for 480 mcg/0.8 mL: From $281.58

Note: Releuko is a specialty injectable, and not all discount programs apply at all pharmacies. Results vary significantly by pharmacy and location.

Prescription Discount Cards for Releuko

Prescription discount cards can reduce the price of Releuko at specialty pharmacies that accept them. The most useful platforms for specialty injectables:

GoodRx — Compare prices across pharmacies and get coupons. As of 2026, GoodRx has priced Releuko as low as $489.87. Valid at 70,000+ pharmacies.

Drugs.com discount cards — Valid at 65,000+ pharmacies. Shows pricing from $179.74 (300 mcg) and $281.58 (480 mcg).

SingleCare — Check pricing for Releuko across nearby pharmacies.

RxSaver and Optum Perks — Additional discount card options worth comparing.

Important: You generally cannot use a prescription discount card in combination with insurance. Choose whichever option is lower for your specific situation.

Amneal Patient Assistance Program

Amneal Pharmaceuticals, the marketer of Releuko, offers patient assistance programs for eligible patients. Contact Amneal directly or have your oncologist's office reach out on your behalf to ask about:

Copay assistance programs for commercially insured patients

Free medication programs for uninsured or underinsured patients who meet income eligibility criteria

Your oncology team's financial navigation staff or social worker can help you apply. These programs often have income-based eligibility requirements and may require documentation from your prescriber.

Third-Party Patient Assistance Programs

If you don't qualify for Amneal's own program, the following organizations may be able to help:

NeedyMeds (needymeds.org) — Searchable database of patient assistance programs by drug name

RxAssist (rxassist.org) — Comprehensive database of manufacturer assistance programs

Patient Advocate Foundation — Copay relief and financial advocacy for cancer patients

HealthWell Foundation — Grants for copayments for oncology treatments

Ask About Biosimilar Alternatives

If your insurance prefers Zarxio or Nivestym and the cost is lower under your plan, ask your oncologist whether switching to the preferred product makes sense. In many cases, all three filgrastim biosimilars (Zarxio, Nivestym, Releuko) are clinically equivalent for the standard chemotherapy neutropenia prevention indication. Following your insurer's preferred product can significantly reduce your out-of-pocket costs with no meaningful clinical trade-off. Biosimilar filgrastim products are typically $200–$350 per injection, representing a substantial saving versus the brand Neupogen.

Insurance Coverage and Medicare

Most commercial insurance plans cover filgrastim biosimilars including Releuko, typically under the medical benefit (for clinic-administered doses) or pharmacy benefit (for home-administered specialty pharmacy fills). Medicare Part B covers Releuko administered in a clinic setting under HCPCS code Q5125. Medicare Part D may cover it if dispensed by a specialty pharmacy. After meeting your deductible, Medicare coinsurance is typically 20% of the Medicare-approved amount. Medigap/supplemental plans may cover that 20%. Your oncologist's financial counselor can help you calculate your expected out-of-pocket cost.

Struggling to find Releuko in the first place? medfinder calls pharmacies near you to check which ones have it in stock. Read our guide on how to find Releuko in stock near you for more tips.