How to Save Money on Pyzchiva in 2026: Coupons, Discounts, and Patient Assistance

Pyzchiva (ustekinumab-ttwe) is a specialty biologic medication, and specialty biologics come with specialty price tags. Stelara — the reference product that Pyzchiva is a biosimilar of — had a list price around $25,497 per 8-week 90 mg dose. Sandoz launched Pyzchiva at approximately 80% below Stelara's list price, but even at that discount, the out-of-pocket cost without insurance or assistance programs can still be thousands of dollars per dose.

The good news: there are several real programs that can dramatically reduce what you pay. Here is a complete breakdown.

What Does Pyzchiva Cost Without Insurance?

Cash prices for Pyzchiva vary by pharmacy and dose. Based on GoodRx and SingleCare pricing data:

• 45 mg/0.5 mL syringe: Starting around $2,047 with a GoodRx coupon
• 90 mg/mL syringe: Starting around $4,087-$4,147 with a GoodRx or SingleCare coupon

Keep in mind that these are per-syringe prices. Depending on your condition and dosing schedule, you may use one syringe every 8 to 12 weeks for ongoing treatment — which adds up to approximately $17,000 to $26,000 per year at cash prices even with GoodRx. This is why insurance coverage and manufacturer assistance programs are so important.

Option 1: Sandoz Co-Pay Assistance Program (Best for Commercially Insured Patients)

The Sandoz Pyzchiva co-pay assistance program is the most powerful savings option for patients with commercial (employer-sponsored or marketplace) insurance. Key details:

• Savings: Out-of-pocket cost can be reduced to as little as $0 per treatment (maximum savings limits may apply)
• Eligibility: Commercially insured patients only (not Medicare, Medicaid, or other government programs)
• How to enroll: Register at pyzchiva.com or call 1-855-726-3698 (1-855-SANDOZ-8)
• Restrictions: The program is not available to patients using accumulator adjustment or maximizer programs. Check with your plan before enrolling.

Option 2: Sandoz Patient Assistance Program (For Uninsured or Underinsured Patients)

If you do not have insurance or do not qualify for commercial co-pay assistance, Sandoz also offers a patient assistance program (PAP) for qualifying patients based on income and insurance status. Through the PAP, eligible patients may receive Pyzchiva at no cost or significantly reduced cost. Contact Sandoz at 1-855-726-3698 or visit pyzchiva.com/support-services/ to learn about PAP eligibility requirements.

Option 3: GoodRx and SingleCare Coupons

GoodRx and SingleCare offer prescription discount coupons that can lower the cash price for Pyzchiva by up to 80% compared to the undiscounted retail price. With a GoodRx coupon, some pharmacies offer a Pyzchiva 90 mg syringe for around $4,147.

Important note: You cannot combine GoodRx with Medicare. If you have commercial insurance, you may also not be able to combine GoodRx with your insurance at the same time — check which option provides the lowest out-of-pocket cost for your specific situation.

Option 4: Medicare Patients — Medicare Part D and Extra Help

Medicare patients cannot use the Sandoz commercial co-pay program. However, there are Medicare-specific options:

• Medicare Part D: As of 2025, Medicare Part D out-of-pocket spending is capped at $2,000 per year. Once you hit the cap, Pyzchiva is covered at 100% for the rest of the year.
• Medicare Part D Extra Help (Low-Income Subsidy): Qualifying low-income Medicare beneficiaries can receive significant help with Part D premiums, deductibles, and co-pays. Contact Social Security at 1-800-772-1213 to apply.
• Medicare Prescription Payment Plan: Starting 2025, Medicare beneficiaries can spread their out-of-pocket drug costs over the year in monthly payments rather than paying large amounts upfront.

Option 5: Ask About Switching to a Biosimilar Your Insurance Covers Better

All ustekinumab biosimilars are clinically equivalent. If your insurance covers Selarsdi, Wezlana, or another ustekinumab biosimilar more favorably than Pyzchiva, switching could reduce your cost significantly without changing how well your treatment works. Talk to your prescriber about which option is most accessible given your specific plan.

Once you have sorted out pricing and insurance, make sure you can actually pick up your medication. medfinder can help you locate pharmacies near you that have Pyzchiva in stock. Learn more in our guide: How to Find Pyzchiva in Stock Near You.