Ofloxacin Is Affordable — But You Can Pay Even Less

Ofloxacin is a generic fluoroquinolone antibiotic used to treat bacterial infections of the urinary tract, respiratory system, skin, eyes, and ears. The good news? As a widely available generic, it's one of the more affordable antibiotics out there. The even better news? With the right discount tools, you can cut the cost even further.

In this guide, we'll break down exactly what Ofloxacin costs in 2026, how to use coupon cards and discount programs, and what patient assistance options are available if you're uninsured or underinsured.

What Does Ofloxacin Cost Without Insurance?

Without insurance or a discount card, here's what you can expect to pay at most pharmacies:

• Oral tablets (generic): $10 to $60 depending on the strength (200 mg, 300 mg, or 400 mg) and quantity
• Ophthalmic solution 0.3% (eye drops): $20 to $57 for a 5 mL bottle
• Otic solution 0.3% (ear drops): $15 to $80 depending on the pharmacy

These are cash prices — what the pharmacy charges if you're paying out of pocket with no insurance and no coupon. The price can vary dramatically from one pharmacy to another, so it always pays to shop around.

How to Save With Coupon and Discount Cards

Prescription discount cards are free to use and can save you up to 80% on generic medications like Ofloxacin. Here's what you can pay with popular discount programs:

GoodRx

• Ofloxacin oral tablets: as low as $2.27
• Ofloxacin ophthalmic solution: as low as $4.77
• GoodRx Gold members may pay as low as $8.35 for certain formulations
• Free to use — just show the coupon at the pharmacy

SingleCare

• Ofloxacin ophthalmic solution: as low as $7.75 for a 5 mL bottle (compared to a cash price of $56.61)
• Oral tablets also available at significant discounts
• Accepted at CVS, Walgreens, Walmart, Rite Aid, and most independent pharmacies

WellRx (ScriptSave)

• Savings of up to 80% on generic Ofloxacin
• Free discount card — no registration required for basic savings

Other Discount Programs

Several other coupon card providers offer competitive pricing on Ofloxacin:

• Optum Perks — search at perks.optum.com
• BuzzRx — check buzzrx.com for Ofloxacin coupons
• RxSaver — compare prices at rxsaver.com
• America's Pharmacy — another option at americaspharmacy.com

Pro tip: Prices vary by pharmacy, so always compare prices across multiple discount cards and multiple pharmacies. The cheapest option at CVS may not be the cheapest at Walmart or Costco.

Does Insurance Cover Ofloxacin?

Yes — generic Ofloxacin is covered by most insurance plans including Medicare Part D. It's typically placed on Tier 1 or Tier 2 of the formulary, which means the lowest copay tier.

A few things to be aware of:

• Prior authorization is generally not required for generic Ofloxacin
• Some insurers may require step therapy documentation for the oral tablets, meaning your doctor may need to show that other antibiotics were tried first or aren't appropriate
• If your insurance copay is higher than the discount card price, you can choose to pay cash with a coupon instead — just ask your pharmacist

Patient Assistance Programs

Since Ofloxacin is a generic-only medication (the brand names Floxin, Ocuflox, and Floxin Otic are all discontinued), there are no manufacturer savings programs or copay cards available. However, patients who are uninsured or have financial hardship can access help through these resources:

NeedyMeds (needymeds.org)

NeedyMeds maintains a comprehensive database of assistance programs, discount cards, and free/low-cost clinic information. Search for Ofloxacin to find applicable programs in your area.

RxAssist (rxassist.org)

RxAssist provides a directory of patient assistance programs offered by pharmaceutical manufacturers and charitable organizations. While there's no Ofloxacin-specific PAP, RxAssist can connect you with general medication assistance resources.

State Pharmaceutical Assistance Programs (SPAPs)

Many states operate their own programs to help residents afford prescription medications. Eligibility varies by state and income level. Check your state's health department website for details.

$4 Generic Programs

Retailers like Walmart and Costco offer generic drug programs with selected medications priced at $4 for a 30-day supply. While Ofloxacin may not be on every $4 list, it's worth checking — and Costco's pharmacy is open to non-members.

Other Ways to Save on Ofloxacin

Ask About the Generic

All Ofloxacin products currently on the market are generic, so there's no brand-name premium to worry about. But always confirm that your pharmacy is dispensing the generic version — not all pharmacists will automatically flag this for you.

Compare Pharmacy Prices

The same generic drug can cost dramatically different amounts at different pharmacies. A few examples:

• Ofloxacin ophthalmic at a chain pharmacy: $45-$57 cash price
• Same medication at Costco or an independent pharmacy: $8-$15 with a discount card

Tools like Medfinder can help you find pharmacies with Ofloxacin in stock, and discount card sites like GoodRx let you compare prices across locations.

Buy a Larger Quantity

For oral tablets, buying a full course (e.g., 20 tablets instead of 10) is sometimes cheaper per pill than buying a smaller quantity. Ask your pharmacist about quantity-based pricing.

Use Mail-Order Pharmacies

If your insurance plan includes a mail-order pharmacy benefit, you may get a 90-day supply for the price of a 60-day supply. This isn't typical for short-course antibiotics, but it's worth knowing for recurring prescriptions.

Final Thoughts

Ofloxacin is already one of the most affordable antibiotics available, with generic oral tablets starting at just $2.27 with a GoodRx coupon and ophthalmic drops starting around $4.77. But if you're paying cash or your insurance copay seems high, there are plenty of ways to bring the cost down further.

Start by comparing prices across pharmacies and discount card programs. If cost is a barrier, explore patient assistance through NeedyMeds or RxAssist. And if you're having trouble finding Ofloxacin in stock at all, use Medfinder to search real-time pharmacy availability.

For more information about this medication, check out our posts on what Ofloxacin is, Ofloxacin side effects, and the Ofloxacin shortage update for 2026.