How to Save Money on Mefloquine in 2026: Coupons, Discounts, and Patient Assistance

Mefloquine is not a cheap medication. At standard retail prices, a course of mefloquine for a typical 8-week trip can cost $90-$120 or more without insurance. But with the right discount tools, you can significantly reduce that cost — often paying under $35 for the same medication. Here's what you need to know.

What Does Mefloquine Typically Cost?

Retail prices for generic mefloquine 250 mg tablets vary considerably by pharmacy. Based on 2025-2026 pricing data:

Average retail price: Approximately $90-$120 for 8 tablets (an 8-week prophylaxis course)

With the free MedFinder savings card coupon: As low as $32.83 — a 71-73% discount off the average retail price

With the free MedFinder savings card coupon: As low as $22.44 per 4 tablets (approximately $44 for an 8-week course)

With Medicare:Some Medicare Part D plans cover mefloquine with copays around $28 — comparable to or less than the free MedFinder savings card pricing

Note: These prices reflect the generic formulation only. The brand-name Lariam was discontinued in the U.S. in 2009 and is not available domestically.

MedFinder savings card

Our free discount card with low prices at 65,000+ pharmacies nationwide. Search your medication, compare the cash price near you, and show the card at the counter to save up to 80%. It's a discount, not insurance, and savings vary by drug and pharmacy. Note: pharmacies can choose not to participate. You can use it whether you find your medication with MedFinder or not.

Does Insurance Cover Mefloquine?

Coverage varies by plan. Generic mefloquine may be covered as a Tier 1 or Tier 2 medication on some plans, but it is not universally covered. Travel medications (including antimalarials) are sometimes classified differently from maintenance medications, and some plans require the medication to be for a covered indication.

To check your coverage:

Call the member services number on your insurance card and ask about coverage for mefloquine hydrochloride 250 mg (generic)

Check your plan's drug formulary online (search for "mefloquine" or "antimalarial")

Compare your insurance copay to the free MedFinder savings card pricing — if the coupon is cheaper, use the coupon

Is There a Patient Assistance Program for Mefloquine?

No manufacturer patient assistance program (PAP) is currently available for mefloquine from Teva. Unlike many brand-name drugs (which often have copay cards or PAPs), generic medications rarely have manufacturer assistance programs. The best savings options remain the free MedFinder savings card, and similar pharmacy discount programs.

Tips to Maximize Your Savings

Compare prices at multiple pharmacies:the free MedFinder savings card pricing varies by pharmacy location. The same prescription can cost very differently between CVS, Walgreens, and Costco.

Fill a larger quantity: If your trip is 10-12 weeks, ask your prescriber for a 90-day supply. Per-tablet cost is often lower when buying more.

Consider Costco pharmacy:Costco pharmacies consistently offer low medication prices, often comparable to or better than the free MedFinder savings card pricing. Non-members can use the pharmacy in many states.

Check RxSaver, Blink Health, and NeedyMeds:These are additional discount platforms that sometimes offer lower prices on specific drugs than the free MedFinder savings card.

The Bottom Line

You don't have to pay full retail price for mefloquine. the free MedFinder savings card can reduce your cost by 70-80%, bringing an 8-week course of mefloquine down to $33-44. Check whether your insurance beats that, and use whichever is cheaper. If you're also struggling to find mefloquine in stock, medfinder can help locate it at pharmacies near you. See our guide: How to Find Mefloquine In Stock Near You.