

Marplan costs $577-$700 without insurance. Learn how to save with co-pay cards, patient assistance programs, and discount strategies in 2026.
If you take Marplan (Isocarboxazid) for depression, you already know it's not a cheap medication. With a cash price of $577 to $700 for a 30-day supply and no generic available, Marplan is one of the most expensive antidepressants on the market. And unlike many brand-name drugs, there's no generic Isocarboxazid to fall back on.
But there are real ways to reduce what you pay. This guide covers every savings option available for Marplan in 2026 — from the manufacturer's co-pay card to patient assistance programs to practical strategies that can bring your costs down significantly.
Let's start with the baseline. If you're paying entirely out of pocket with no insurance and no discount programs:
These prices make Marplan unaffordable for most patients without some form of assistance. The good news is that several programs exist specifically to help.
Validus Pharmaceuticals, the maker of Marplan, offers a co-pay savings card that can dramatically reduce your out-of-pocket costs:
Who qualifies: Patients with commercial (private) insurance. The card is NOT valid for patients with government insurance including Medicare, Medicaid, Tricare, or VA benefits.
How to get it: Visit marplan.com or ask your pharmacist about the Marplan co-pay card. Your pharmacy can process it as a secondary payer after your insurance.
This is the single best savings option for most commercially insured patients.
If you don't have insurance or your insurance doesn't cover Marplan, prescription discount cards can help reduce the cash price:
These cards are free to use and don't require insurance. Simply present the card or coupon code at the pharmacy when filling your prescription. Note that you typically cannot combine a discount card with insurance — you use one or the other, whichever gives you the lower price.
Important: Prices vary by pharmacy, so always compare across multiple locations. The same discount card can show different prices at different pharmacies.
If you're uninsured, underinsured, or have a low income, patient assistance programs (PAPs) can make Marplan much more affordable — or even free.
Prescription Hope offers Marplan for $70 per month (a flat service fee). They work directly with pharmaceutical manufacturers to help patients access their medications at a fraction of the retail cost.
NeedyMeds (needymeds.org) is a nonprofit database that lists patient assistance programs, discount cards, and other savings resources for thousands of medications including Marplan. They can help you find programs you might not know about.
RxAssist (rxassist.org) is another comprehensive database of patient assistance programs. Search for Isocarboxazid or Marplan to find current options.
Contact Validus Pharmaceuticals directly at 1-866-982-5438 to ask about patient assistance options. Manufacturers sometimes have programs that aren't widely advertised, particularly for patients who are uninsured or facing financial hardship.
If your insurance covers 90-day fills (common with mail-order pharmacies), this can reduce your per-fill costs and copay frequency. With the manufacturer co-pay card, a 90-day supply gets up to $200 in savings — more efficient than three separate 30-day fills.
Marplan prices can vary significantly between pharmacies — sometimes by hundreds of dollars. Before filling your prescription, check prices at:
If your insurance denies coverage for Marplan, don't give up. You have the right to appeal, and your doctor can submit a prior authorization with documentation of failed trials on other antidepressants. Many denials are overturned on appeal, especially when there's clear evidence that Marplan is medically necessary.
Some states offer their own prescription assistance programs for residents who don't qualify for Medicaid but still struggle to afford medications. Check with your state's department of health or aging services.
If cost is a significant barrier and savings programs don't bring Marplan into an affordable range, talk to your psychiatrist about whether a different MAOI might be more affordable. Parnate (Tranylcypromine), for example, is available in generic form in some markets and may cost less. Read more in our guide to Marplan alternatives.
Paying $577 to $700 per month for a medication is not sustainable for most people. But between the manufacturer co-pay card ($20/month for insured patients), Prescription Hope ($70/month), discount cards like GoodRx ($577 vs. $693), and other assistance programs, most patients can bring the cost of Marplan down to a manageable level.
Start by checking whether you qualify for the Marplan co-pay card, then explore patient assistance programs if you're uninsured. And always compare prices across pharmacies — the difference can be hundreds of dollars.
Need help finding Marplan in stock? Use Medfinder to check real-time availability at pharmacies near you. For more about the current supply situation, read our Marplan shortage update for 2026.
You focus on staying healthy. We'll handle the rest.
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