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Updated: January 21, 2026

How to Save Money on Klisyri in 2026: Coupons, Discounts, and Patient Assistance

Author

Peter Daggett

Peter Daggett

Klisyri medication bottle next to savings piggy bank and discount tag

Klisyri can cost nearly $2,000 at retail, but you may not have to pay anywhere close to that. Here are the best savings programs and coupons for Klisyri in 2026.

Klisyri (tirbanibulin) is one of the more expensive topical dermatology prescriptions on the market, with a retail price of approximately $1,959–$1,967 for a 5-packet course. But the actual amount you pay could be dramatically lower — sometimes as little as $25 — depending on your insurance and which savings programs you use. Here's your complete guide to Klisyri savings in 2026.

Why Is Klisyri So Expensive?

Klisyri is a brand-name-only drug — no generic version of tirbanibulin exists as of 2026. This means the manufacturer, Almirall, LLC, controls pricing without generic competition. Brand specialty dermatology drugs routinely carry retail prices of $1,000–$3,000 per course when no generic is available. Until a generic tirbanibulin reaches the market, the list price will remain high.

Option 1: Almirall Advantage Co-Pay Card (Commercially Insured Patients)

If you have commercial (private, employer-sponsored) insurance, the Almirall Advantage copay card is likely your best option. Here's how it works:

Commercially insured patients pay as low as $25 per fill when filling at an Almirall Advantage Network pharmacy

If your commercial insurance doesn't cover Klisyri, you can still use the card and pay as low as $150 at retail or $95 at an in-network pharmacy

NOT available to patients with Medicare (Part A, B, C, or D), Medicaid, or other federal healthcare programs

Savings may be subject to maximum benefit limits — review the current terms at almiralladvantage.com

To use this program, ask your dermatologist to route your prescription to an Almirall Advantage Network pharmacy. The pharmacist will apply the savings at the point of sale.

Option 2: GoodRx Coupon (Available to Anyone)

GoodRx offers a coupon for Klisyri that can bring the retail price down significantly. Recent GoodRx pricing shows Klisyri available for as low as $280.79, compared to the retail price of approximately $1,959 — a savings of about 86%. GoodRx coupons:

Are available to everyone, including Medicare patients

Cannot be combined with insurance or the Almirall Advantage copay card — use one or the other

Prices vary by pharmacy and location — always check goodrx.com for the current lowest price near you

Not insurance — using GoodRx does not count toward your insurance deductible

Option 3: SingleCare, WellRx, and Other Discount Cards

Other pharmacy discount programs — including SingleCare, WellRx, Blink Health, and RxSaver — may also offer Klisyri discounts. Prices vary, and it's worth checking multiple services to compare. These work similarly to GoodRx: you show the discount card or code at the pharmacy counter and pay the discounted cash price.

Option 4: Insurance with Prior Authorization

If your insurance plan covers Klisyri after prior authorization and step therapy, your cost may be limited to your standard specialty drug copay or coinsurance — typically $30–$100 for a commercially insured patient. The key steps:

Ask your dermatologist to submit a prior authorization request for Klisyri

Ensure your medical record documents any prior AK treatments that didn't work for you

If denied, ask your doctor to appeal — many appeals are successful with the right documentation

Option 5: Patient Assistance Programs

For patients who have no insurance and cannot afford even the discounted cash price, manufacturer patient assistance programs (PAPs) may provide Klisyri at no cost or reduced cost. Contact Almirall directly at 1-866-665-2782 to inquire about current PAP eligibility requirements, which typically include income limits and proof of no insurance coverage.

Quick Comparison: Klisyri Savings Options in 2026

Retail (no discount): ~$1,959–$1,967

GoodRx coupon: As low as ~$280.79

Almirall Advantage (no coverage): As low as $95 (in-network) or $150 (retail)

Almirall Advantage (commercial insurance): As low as $25

Insurance (with PA approved): Standard specialty copay ($30–$100 typically)

Still Having Trouble Finding Klisyri to Fill?

Even after securing the right savings program, you still need a pharmacy that carries Klisyri. Use medfinder to find which pharmacies near you have it in stock. For a full pharmacy search guide, see how to find Klisyri in stock near you.

Frequently Asked Questions

With a GoodRx coupon, Klisyri (tirbanibulin) 1% ointment (5-packet carton) costs as low as $280.79 — approximately 86% off the retail price of about $1,959. Prices vary by pharmacy and location; check goodrx.com for the most current price near you. GoodRx can be used by anyone, including Medicare patients.

No. The Almirall Advantage co-pay card is not available to patients with Medicare (including Part D), Medicaid, or other federal government health programs. Medicare patients should compare their Part D coverage with GoodRx pricing. Contact Almirall at 1-866-665-2782 to inquire about patient assistance program eligibility.

Many commercial insurance plans cover Klisyri, but usually only after prior authorization and step therapy — meaning you must first try and fail two other AK treatments (typically diclofenac gel, fluorouracil cream, or imiquimod cream). When approved, your cost is limited to your standard specialty copay. Some Medicare Part D plans also cover Klisyri; coverage varies by plan.

Klisyri's 5-day treatment course is its primary advantage over cheaper alternatives like fluorouracil ($30–$80, 2–4 week course) or imiquimod ($30–$80, 4-week course). A 2023 economic evaluation found tirbanibulin to be cost-competitive with older AK treatments when accounting for adherence rates, fewer severe skin reactions, and treatment completion. If cost is a barrier, speak with your dermatologist about which alternative best fits your situation.

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