Ibrexafungerp (Brexafemme) can cost $700-$900 without insurance. Learn how to save with coupons, discount cards, and patient assistance programs.
Ibrexafungerp, sold under the brand name Brexafemme, is the only oral non-azole antifungal approved for vaginal yeast infections. It's a groundbreaking medication — but with a cash price of approximately $700 to $900 for a single treatment course, it's also one of the most expensive options for a condition that many women deal with repeatedly.
If you've been hit with sticker shock at the pharmacy, don't give up on your prescription just yet. There are real ways to bring down the cost of Ibrexafungerp in 2026. This guide walks you through your options.
A full treatment course of Brexafemme consists of four 150 mg tablets (two taken in the morning, two taken in the evening). Without insurance or a discount program, the cash price at most pharmacies ranges from approximately:
Prices vary by pharmacy, so it's worth shopping around. But even the lowest cash prices are significantly higher than alternatives like generic Fluconazole, which costs $4 to $15 per dose.
Several prescription discount services may help reduce the price of Brexafemme. While savings vary by pharmacy and location, these are worth checking:
Keep in mind that for a brand-name drug with no generic, discount card savings may be modest. But it's still worth comparing — even a small percentage off an $800 prescription adds up.
The most significant savings option for most patients is the Brexafemme Savings Card offered directly by the manufacturer, Scynexis, Inc.
If you have commercial insurance, this should be your first stop. Even if your plan requires a high copay or coinsurance, the savings card can dramatically reduce your out-of-pocket cost.
If you're uninsured or underinsured, patient assistance programs (PAPs) can provide Brexafemme at reduced cost or free of charge:
Several organizations help patients find financial assistance for prescription medications:
If you have insurance, call your plan's pharmacy helpline and ask:
Many plans will cover Brexafemme after prior authorization, especially if you've tried and failed Fluconazole. Your doctor can submit the necessary paperwork — ask them to initiate this process when they write the prescription.
Prices for Brexafemme can vary between pharmacies. Use tools like GoodRx, SingleCare, or Medfinder to compare prices at different pharmacies in your area. Specialty pharmacies and mail-order services sometimes offer better pricing.
If cost is the primary barrier, talk to your doctor about whether an alternative would work for your situation. For uncomplicated yeast infections:
For a full comparison, read alternatives to Ibrexafungerp.
Ibrexafungerp (Brexafemme) is an important medication, but its high cost is a real barrier for many patients. The good news is that between the manufacturer's savings card, patient assistance programs, prescription discount cards, and insurance coverage, most patients can bring the cost down significantly.
Start with the Brexafemme Savings Card if you have commercial insurance. If you're uninsured, contact Scynexis directly at 1-888-982-7299 to learn about their assistance program. And always compare prices at different pharmacies using Medfinder or discount card websites.
For help finding a pharmacy that has Brexafemme in stock, check out how to find Ibrexafungerp in stock near you.
You focus on staying healthy. We'll handle the rest.
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