Humira Is One of the Most Expensive Medications in America — But You Don't Have to Pay Full Price

Let's start with the number that stops most people in their tracks: without insurance, the Humira Pen 40 Mg/0.4 Ml costs anywhere from $7,300 to $11,000 per carton of just 2 pens. That's a monthly supply for most patients — and it adds up to over $80,000 per year at full price.

The good news? Almost nobody actually pays that amount. Between manufacturer savings programs, insurance coverage, patient assistance programs, and biosimilar alternatives, there are real ways to bring your costs down dramatically.

This guide covers every option available in 2026 to help you save money on Humira.

How Much Does Humira Cost Without Insurance?

Here's what you're looking at without any form of assistance:

• Humira Pen 40 mg/0.4 mL (2-pen carton): $6,900 to $11,000 (list price ~$6,900; retail cash price varies by pharmacy)
• Annual cost at maintenance dosing (every other week): Approximately $80,000 to $90,000
• Starter pack cost: May be higher due to additional pens included for induction dosing

These numbers are based on list prices and average cash prices reported by GoodRx and Drugs.com. Actual pricing varies by pharmacy.

Coupons and Discount Cards

HUMIRA Complete Savings Card (AbbVie)

This is the most impactful savings tool for commercially insured patients:

• Eligible patients pay as little as $5 per month for Humira
• AbbVie covers the remaining copay, coinsurance, or deductible costs
• Available to patients with commercial (private) insurance only
• Not available to patients with Medicare, Medicaid, Tricare, or other government insurance
• Must re-enroll annually
• Enroll at humira.com or call 1-800-4HUMIRA (1-800-448-6472)

This savings card is by far the most common way Humira patients reduce their out-of-pocket costs. If you have commercial insurance, this should be your first step.

Pharmacy Discount Cards

If you don't have insurance, pharmacy discount cards like GoodRx, SingleCare, and RxSaver may offer some savings on Humira. However, because Humira is a specialty biologic, discount card savings are typically modest compared to the manufacturer program. Expect to still pay $7,000+ per carton even with a discount card.

These cards are more useful for biosimilar alternatives, where the base price is much lower.

Patient Assistance Programs

myAbbVie Assist

For patients who are uninsured or underinsured, AbbVie offers free Humira through their patient assistance program:

• Eligibility: U.S. residents without insurance coverage for Humira, or those who cannot afford their out-of-pocket costs
• Income requirements: Based on household income and family size (specific thresholds vary)
• What you get: Free Humira shipped directly to you or your doctor's office
• How to apply: Download the application at abbvie.com or call 1-800-4HUMIRA

PAN Foundation

The Patient Access Network (PAN) Foundation offers financial assistance for underinsured patients taking Humira for qualifying conditions. Grants help cover out-of-pocket costs including copays, coinsurance, and deductibles.

• Check availability at panfoundation.org
• Funding varies by disease fund and may open/close periodically

HealthWell Foundation

Similar to PAN, the HealthWell Foundation provides copay assistance for patients meeting financial eligibility criteria. Visit healthwellfoundation.org to check for open funds related to your condition.

Patient Advocate Foundation

Offers a Co-Pay Relief Program for patients with specific diagnoses. Visit copays.org to check eligibility.

Medicare Part D Savings in 2026

If you're on Medicare Part D, there's important good news for 2026:

• The Inflation Reduction Act caps total out-of-pocket prescription drug spending at $2,100 per year for Medicare Part D beneficiaries in 2026.
• This means even for a high-cost drug like Humira, your annual maximum out-of-pocket cost is capped at $2,100.
• Many Medicare Part D plans also offer the Medicare Prescription Payment Plan, which lets you spread your costs evenly across monthly payments instead of paying large amounts upfront.

Contact your Medicare Part D plan to enroll in the payment plan option.

Switch to a Biosimilar to Save Big

The most dramatic way to save on Adalimumab therapy in 2026 is to switch from brand-name Humira to a biosimilar. The savings are substantial:

• Hadlima (Adalimumab-bwwd): ~$1,038 per carton — savings of approximately $5,860 per month vs. brand-name Humira
• Unbranded Hyrimoz (Adalimumab-adaz): ~$1,315 per carton — savings of approximately $5,585 per month
• Amjevita (Adalimumab-atto): ~$3,100 per carton — savings of approximately $3,800 per month

These biosimilars contain the same active ingredient and are FDA-approved for the same conditions. Several are designated as interchangeable, meaning your pharmacist may be able to substitute without a new prescription.

Talk to your doctor about whether a biosimilar is right for you. For a full comparison, see our guide to Humira alternatives.

Other Ways to Save

Ask About Step Therapy Credits

If you've already tried and failed other treatments (like Methotrexate), make sure your doctor documents this in your medical records. This can expedite prior authorization and help you avoid unnecessary step therapy requirements that delay access to the medication you need.

Appeal Insurance Denials

If your insurance denies coverage for Humira, you have the right to appeal. Work with your doctor's office to submit an appeal with clinical documentation explaining why Humira (or a specific formulation) is medically necessary for your condition.

Shop Around for Pharmacies

Cash prices for Humira vary significantly between pharmacies. Use Medfinder to compare availability and pricing in your area.

Consider Mail-Order Specialty Pharmacies

Specialty pharmacies that ship to your home sometimes offer better pricing than retail pharmacies, particularly when combined with manufacturer savings programs.

Quick Reference: Humira Savings Options at a Glance

• Commercially insured: HUMIRA Complete Savings Card → as low as $5/month
• Medicare Part D: $2,100 annual out-of-pocket cap in 2026
• Uninsured: myAbbVie Assist → free medication if eligible
• Underinsured: PAN Foundation, HealthWell Foundation, Patient Advocate Foundation
• Anyone: Switch to biosimilar → save $3,800 to $5,860/month

Final Thoughts

Nobody should have to skip doses or stop treatment because of cost. Whether you have commercial insurance, Medicare, or no insurance at all, there are programs and alternatives that can make Humira or its biosimilars affordable in 2026.

Start with the HUMIRA Complete Savings Card if you're commercially insured, explore myAbbVie Assist if you're uninsured, and seriously consider biosimilar options if cost is a primary concern. Use Medfinder to find the best availability and pricing near you.

For more information about finding the medication, see our guide on how to find Humira in stock near you. And to learn about finding a prescriber, check out how to find a doctor who prescribes Humira near you.