Save on Estradiol/Norethindrone in 2026. Compare cash prices, discount cards, coupons, and patient assistance programs to lower your monthly cost.
If you've been hit with sticker shock at the pharmacy, you're not alone. The cash price for Estradiol/Norethindrone can range from $50 to over $200 per month depending on whether you're getting the generic or brand-name version, and which formulation you use.
The good news? There are real ways to bring that cost down — sometimes dramatically. In this guide, we'll walk through exactly what Estradiol/Norethindrone costs in 2026, and every option available to help you save.
Here's what you can expect to pay at retail (without insurance) for a 30-day supply:
These prices can vary significantly by pharmacy. Large chain pharmacies often charge more than independent pharmacies for the same generic medication.
Prescription discount cards are free to use and can dramatically lower the price of generic Estradiol/Norethindrone. Here are the most popular options:
GoodRx is one of the most widely used prescription discount tools. For generic Estradiol/Norethindrone oral tablets, GoodRx shows prices as low as $48.53 with GoodRx Gold (a paid membership) and competitive free coupon prices at many pharmacies. Prices vary by pharmacy, so always compare.
SingleCare offers free coupons that can be used at most major pharmacies including CVS, Walgreens, and Walmart. Prices for generic Estradiol/Norethindrone are often comparable to GoodRx. Check singlecare.com for current pricing.
RxSaver compares prices across multiple discount programs to find the lowest price near you. Visit rxsaver.com to search for Estradiol/Norethindrone coupons.
These services also offer free or low-cost prescription coupons:
Pro tip: Compare prices on 2 to 3 discount card sites before filling your prescription. Prices can vary by $20 or more for the same medication at the same pharmacy depending on which card you use.
If you're uninsured, underinsured, or struggling to afford your medication, patient assistance programs (PAPs) may provide Estradiol/Norethindrone at no cost.
Novo Nordisk, the manufacturer of brand-name Activella, offers a Patient Assistance Program that provides the medication for free to qualifying patients. To be eligible, you generally must:
Contact: 1-866-668-6336 or visit novonordisk-us.com for application details.
NeedyMeds is a nonprofit database that lists patient assistance programs, copay cards, and other savings resources. Search for Estradiol/Norethindrone to see all available programs.
RxAssist is another comprehensive database of patient assistance programs maintained by Volunteers in Health Care. It can help you find programs for both brand and generic medications.
RxHope connects patients with manufacturer-sponsored assistance programs. Your doctor's office can submit an application on your behalf.
The generic version of Estradiol/Norethindrone costs significantly less than brand-name products. Brand Activella can cost $150 to $200+ per month, while generics with a discount card can be $15 to $50 per month. That's a savings of up to $150 or more every month.
Ask your doctor to write your prescription for generic Estradiol/Norethindrone Acetate, and make sure the prescription allows generic substitution.
Prices for the same generic medication can differ by $30 or more between pharmacies in the same neighborhood. Independent pharmacies, Costco, and Walmart often have lower prices than chain pharmacies. Use Medfinder to check both availability and pricing.
Many pharmacies and insurance plans offer a lower per-month cost when you fill a 90-day supply instead of 30 days. This is especially true for mail-order pharmacies. Ask your pharmacist or insurance company about this option.
If you have insurance, Estradiol/Norethindrone generic tablets are typically covered on Tier 2 or Tier 3 of most formularies. Your copay may be $10 to $45 per month. Some tips:
Walmart's $4 prescription program covers select generic medications. While Estradiol/Norethindrone may not always be on the list, it's worth checking. Visit walmart.com for the current list of covered medications.
Mark Cuban Cost Plus Drugs is an online pharmacy that sells generic medications at cost plus a small markup. Check their website to see if Estradiol/Norethindrone is available.
No one should have to skip their hormone replacement therapy because of cost. Between discount cards, patient assistance programs, generic options, and smart pharmacy shopping, most women can find a way to afford Estradiol/Norethindrone in 2026.
Start by comparing prices with a discount card, ask about generics, and explore patient assistance if you're uninsured. And if you're having trouble finding the medication in stock, use Medfinder to locate a pharmacy near you that has it available.
For more information about this medication, read our guides on what Estradiol/Norethindrone is and Estradiol/Norethindrone side effects.
You focus on staying healthy. We'll handle the rest.
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