

Duloxetine can cost $130-$230/month without insurance. Learn how to pay as little as $4 with coupons, discount cards, and patient assistance programs.
If you take Duloxetine (brand name Cymbalta) for depression, anxiety, fibromyalgia, or chronic pain, you know it's an important medication. But even though generic Duloxetine is available, the cost can still add up — especially without insurance. The retail cash price for a 30-day supply of Duloxetine 60 mg can run $130 to $230, and brand-name Cymbalta can exceed $400 per month.
The good news? With the right tools and programs, you can pay as little as $4 to $15 per month for generic Duloxetine. Here's how.
Let's start with the baseline. If you walk into a pharmacy and pay cash without any discounts, here's what you can expect to pay for a 30-day supply:
These prices vary by pharmacy and location, which is why shopping around — and using coupons — can save you hundreds of dollars.
Prescription discount cards and coupons are the single easiest way to save on Duloxetine. These are free to use and accepted at most pharmacies. Here are the most popular options:
GoodRx is one of the most well-known prescription discount platforms. For generic Duloxetine 60 mg (30 capsules), GoodRx coupons typically bring the price down to $10 to $15 at most major pharmacies. Prices can be even lower at Costco or certain independent pharmacies.
SingleCare offers competitive pricing on Duloxetine. You can often find generic Duloxetine 60 mg for $8 to $15 using a SingleCare card. It's accepted at CVS, Walgreens, Walmart, and thousands of other pharmacies.
RxSaver compares prices across multiple discount programs to help you find the lowest price. Generic Duloxetine often shows up at $4 to $12 through their platform.
Additional discount card providers include:
Pro tip: Prices vary by pharmacy, so always compare multiple pharmacies on your coupon platform before filling. Costco, Walmart, and independent pharmacies frequently offer the lowest prices.
Online pharmacies can offer some of the best prices on generic Duloxetine:
Mail-order pharmacies are a good option if you take Duloxetine regularly and want to save money on 90-day supplies, which often offer even better per-month pricing.
If you're uninsured or underinsured and struggling to afford Duloxetine, patient assistance programs (PAPs) may provide your medication at no cost or very low cost:
The Lilly Cares Foundation Patient Assistance Program provides brand-name Cymbalta at no cost to eligible patients. Eligibility is typically based on:
Your doctor will need to submit an application on your behalf. Learn more at the Lilly Cares website or through RxAssist.
NeedyMeds is a comprehensive database of patient assistance programs, including those for Duloxetine. They also offer a free NeedyMeds drug discount card.
RxAssist and RxHope are additional resources that help patients locate manufacturer PAPs and other assistance options. Both are free to use.
If you have insurance, make sure you're maximizing your benefits:
If you take Drizalma Sprinkle, be aware that it's generally more expensive than standard Duloxetine capsules ($200-$350/month retail). If cost is a concern and you can swallow standard capsules, talk to your doctor about switching to regular generic Duloxetine to save money.
Duloxetine is one of the more affordable antidepressant and pain medications available, especially as a generic. With discount coupons, the cost can drop to as little as $4 per month — less than a cup of coffee. Don't pay more than you have to.
Start by checking prices on GoodRx, SingleCare, or RxSaver. If you're uninsured, look into patient assistance programs through NeedyMeds or the Lilly Cares Foundation. And if you're having trouble finding Duloxetine in stock, use Medfinder to locate a pharmacy near you.
For more information:
You focus on staying healthy. We'll handle the rest.
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