Droxidopa is expensive — but you have more options than you think

If you've seen the price tag on Droxidopa (brand name: Northera), you know it's not cheap. At full retail price, a month's supply can cost $2,700 to $3,100 — making it one of the most expensive medications many patients with neurogenic orthostatic hypotension (nOH) will ever need.

But here's the good news: almost nobody should be paying that full price. Between generic versions, discount coupons, manufacturer programs, and patient assistance, there are real ways to bring the cost of Droxidopa down to a manageable level. In this guide, we'll walk through every option available in 2026.

How much does Droxidopa cost without insurance?

Let's start with the baseline numbers:

• Brand-name Northera: Approximately $2,700 to $3,100 per month for 90 capsules (a typical 30-day supply at three capsules daily) at retail pharmacies without any discounts.
• Generic Droxidopa (retail price): The average retail price for generic droxidopa is around $2,700 per month for 90 capsules of 100 mg — but this is the sticker price before any coupons or discounts are applied.

These prices are for cash-paying customers at a retail pharmacy. Fortunately, there are many ways to pay far less.

Coupons and discount cards

Prescription discount cards are one of the fastest and easiest ways to save on generic Droxidopa. These are free to use and work even if you don't have insurance.

GoodRx

GoodRx offers coupons that can bring the price of generic droxidopa down to as low as $37 per month for 90 capsules — that's a savings of over 99% compared to the retail price. Prices vary by pharmacy, so check GoodRx for the best price near you.

SingleCare

SingleCare offers Droxidopa coupons starting at approximately $72 for 90 capsules of the 100 mg generic. Like GoodRx, SingleCare is free to use and accepted at most major pharmacies.

Other discount programs

Additional discount card programs that may offer savings on Droxidopa include:

• RxSaver
• Optum Perks
• BuzzRx
• ScriptSave WellRx
• America's Pharmacy

Pro tip: Prices can vary significantly between pharmacies even with the same coupon. Always compare prices at 3-4 pharmacies using your preferred discount card before filling.

Manufacturer savings program

If you take brand-name Northera and have commercial insurance, the manufacturer offers a copay assistance program:

Northera Commercial Copay Assistance Program

• Who qualifies: Commercially insured patients age 17 and older whose insurance covers Northera
• What it does: Reduces your out-of-pocket copay for Northera prescriptions
• How to enroll: Visit activatethecard.com/7773 or call 1-855-820-6768
• Limitations: Not available for patients with government insurance (Medicare, Medicaid, Tricare, VA)

This program can make a significant difference if your insurance covers Northera but leaves you with a high copay or coinsurance.

Patient assistance programs

If you're uninsured, underinsured, or on a fixed income, patient assistance programs (PAPs) can provide Droxidopa at little or no cost:

Prescription Hope

Prescription Hope offers Northera (Droxidopa) for $70 per month for qualifying patients. They handle the enrollment paperwork and work directly with the manufacturer's assistance program on your behalf.

Lundbeck Patient Assistance Program

Lundbeck, the manufacturer of Northera, offers a patient assistance program for eligible uninsured and underinsured patients. Contact Northera patient support at 1-855-820-6768 to learn about eligibility and enrollment.

NeedyMeds and RxAssist

Both NeedyMeds and RxAssist maintain databases of patient assistance programs and can help you find additional resources for Droxidopa.

Other ways to save on Droxidopa

Ask for generic Droxidopa

If your doctor has written a prescription for brand-name Northera, ask if you can switch to generic droxidopa. The generic version contains the same active ingredient and is significantly cheaper — especially when combined with a discount coupon. With GoodRx, generic Droxidopa can cost as little as $37/month compared to $2,700+/month for the brand.

CivicaScript nonprofit generic

In April 2025, CivicaScript — a nonprofit company backed by Blue Cross Blue Shield — launched a generic droxidopa at approximately $2,100 per month less than typical Medicare Part D costs. If you're a member of a participating BCBS plan, ask your pharmacy or insurance about accessing the CivicaScript version.

Compare pharmacy prices

Droxidopa prices vary widely between pharmacies. Use Medfinder to find pharmacies with Droxidopa in stock, then compare coupon prices at each location. Independent pharmacies sometimes offer better pricing than large chains.

Check for state pharmaceutical assistance programs

Some states offer additional pharmaceutical assistance programs for residents with chronic conditions. Check with your state's health department or a social worker at your healthcare provider's office.

Appeal insurance denials

If your insurance denies coverage for Droxidopa, don't give up. Ask your doctor to submit an appeal with documentation of your nOH diagnosis and prior treatment trials. Many denials are overturned on appeal, especially with supporting medical records.

Final thoughts

Droxidopa doesn't have to break the bank. While the sticker price is daunting, generic versions with discount coupons can bring your cost down to as little as $37 per month. Manufacturer copay programs, patient assistance programs, and nonprofit generics provide additional layers of savings.

The key is knowing your options and being proactive. If you need help finding Droxidopa at an affordable price near you, start with Medfinder to check real-time pharmacy availability and pricing.

For more on finding Droxidopa in stock, see: How to find Droxidopa in stock near you. And if cost is driving you to consider other options, read: Alternatives to Droxidopa.