How to Save Money on Depo-SubQ Provera 104 in 2026: Coupons, Discounts, and Patient Assistance

Depo-SubQ Provera 104 is a brand-name injectable contraceptive with no FDA-approved generic — which means the retail cash price can feel steep. But there are several legitimate ways to lower what you pay, whether you have insurance or not. This guide breaks down every major savings option available in 2026.

What Does Depo-SubQ Provera 104 Cost Without Insurance?

Without insurance or a discount program, Depo-SubQ Provera 104 typically costs between $59 and $100 per prefilled syringe (one injection, covering approximately 3 months). Since there's no generic, there's no lower-cost equivalent — but you can still significantly reduce what you pay through the options below.

Option 1: ACA-Compliant Insurance — $0 Copay for Contraception

Under the Affordable Care Act (ACA), most private health insurance plans are required to cover FDA-approved contraceptive methods with no copay when used for contraception. Depo-SubQ Provera 104 is a covered ACA preventive care medication, which means that if you have ACA-compliant insurance and you're using it for birth control, you should pay $0 out of pocket.

Important: If your plan requires prior authorization for a specific brand or the injection is received at a non-in-network provider, you may face cost-sharing. Always verify with your insurance before your appointment.

Option 2: Pfizer RxPathways — Patient Assistance Program

Pfizer offers a patient assistance program called RxPathways that may provide Depo-SubQ Provera 104 at no cost for eligible patients. Eligibility is generally based on income and insurance status — most uninsured or underinsured patients with limited income will qualify. Insured patients and those on Medicare Part D may also be eligible under certain criteria.

Program: Pfizer RxPathways

Phone: 1-877-744-5675

Website: pfizerrxpathways.com

How to apply: Complete the application online or with your doctor's help; submit by mail or fax.

Option 3: GoodRx and SingleCare Discount Cards

Pharmacy discount programs like GoodRx and SingleCare can reduce the cash price of Depo-SubQ Provera 104. With these discount cards, the price typically starts around $53–$59 per injection — a meaningful reduction from the retail cash price.

GoodRx: Check goodrx.com for your ZIP code — prices vary by pharmacy.

SingleCare: Reports Depo-SubQ Provera 104 starting at approximately $53.48 with their coupon at participating locations.

These cards work at most major retail pharmacies. Note: They cannot be combined with insurance — you'll typically use whichever gives you the lower price.

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Option 4: Federally Qualified Health Centers (FQHCs) and Title X Clinics

Federally Qualified Health Centers and Title X family planning clinics offer contraceptive services on a sliding-scale fee basis, meaning cost is based on your income. For uninsured patients or those with very low income, these clinics may provide Depo-SubQ Provera 104 (or its alternatives) at little or no cost. Search for FQHCs at findahealthcenter.hrsa.gov.

Option 5: Medicaid Coverage

If you qualify for Medicaid, contraceptive injectable medications including Depo-SubQ Provera 104 are typically covered at very low or $0 copay. Coverage specifics vary by state, so confirm with your state Medicaid program.

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What About the Endometriosis Indication — Is Coverage Different?

The ACA zero-copay mandate applies specifically to FDA-approved contraceptives used for contraception. If Depo-SubQ Provera 104 is prescribed primarily for endometriosis pain management rather than contraception, standard drug benefits may apply, and you may have a copay. In this case, the Pfizer RxPathways program and discount cards are your best cost-reduction options. Some plans may also require prior authorization for the endometriosis indication.

Savings Summary Table

ACA insurance (contraception): $0 copay at in-network providers

Pfizer RxPathways: Potentially $0 for eligible uninsured/underinsured patients

GoodRx / SingleCare: Starting around $53–$59 per injection

FQHC / Title X clinics: Sliding scale, potentially $0 for low-income patients

Medicaid: Very low or $0 copay for eligible beneficiaries

Once you've sorted out your coverage, use medfinder to find which pharmacies near you have Depo-SubQ Provera 104 in stock at the best price. Knowing both cost and availability in advance helps you plan your next injection with confidence.

For tips on finding the medication at a pharmacy, see our guide: How to find Depo-SubQ Provera 104 in stock near you.