How to Save Money on Ciprofloxacin/Hydrocortisone in 2026: Coupons, Discounts, and Patient Assistance

Updated:

February 17, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Cipro HC ear drops are expensive. Learn how to save on Ciprofloxacin/Hydrocortisone in 2026 with coupons, the new generic, discount cards, and patient assistance.

Ciprofloxacin/Hydrocortisone Can Be Expensive — Here's How to Pay Less

If you've been prescribed Ciprofloxacin/Hydrocortisone (Cipro HC Otic) ear drops and checked the price, you might be in for some sticker shock. Brand-name Cipro HC can cost $350 to $480 for a single 10 mL bottle without insurance. That's a lot to pay for a week's worth of ear drops.

The good news? There are now more ways to save than ever before, thanks to the launch of the first generic in December 2025. In this guide, we'll walk through every option for reducing your out-of-pocket cost in 2026.

What Does Ciprofloxacin/Hydrocortisone Cost Without Insurance?

Here's what you might pay at a typical retail pharmacy in 2026 without any insurance or discount:

  • Brand-name Cipro HC Otic (10 mL): $350 to $480
  • Generic Ciprofloxacin/Hydrocortisone by Cosette (10 mL): $70 to $150

The generic represents a savings of 60% to 80% compared to the brand. Always ask your pharmacist for the generic version — it's the same medication (ciprofloxacin 0.2% / hydrocortisone 1%) at a fraction of the cost.

The New Generic: Your Biggest Savings Opportunity

The single biggest cost-saving development for Ciprofloxacin/Hydrocortisone patients is the first-ever generic, approved by the FDA in December 2025 and manufactured by Cosette Pharmaceuticals.

Key facts about the generic:

  • It's bioequivalent to brand Cipro HC — same active ingredients, same strength, same dosage form
  • Estimated retail price: $70 to $150 per 10 mL bottle
  • Cosette has 180 days of exclusivity (through approximately June 2026), after which additional generics may enter and further drive prices down
  • Most pharmacies will automatically substitute the generic unless your doctor writes "Dispense As Written"

If your pharmacy doesn't have the generic yet, ask them to order it — or use Medfinder to find a pharmacy that stocks it.

Coupons and Discount Cards

Even if you have insurance, a discount card can sometimes beat your copay. And if you're uninsured, they're essential. Here are the top options:

GoodRx

GoodRx shows prices at pharmacies near you and offers free coupons. For brand Cipro HC, prices start around $351 with a GoodRx coupon. Generic pricing is still being established on the platform but should be significantly lower.

SingleCare

SingleCare offers coupons that can bring brand Cipro HC down to around $130 at select pharmacies. Check singlecare.com for current pricing.

RxSaver

RxSaver compares prices across nearby pharmacies. It's another free tool that can help you find the lowest price for both brand and generic Ciprofloxacin/Hydrocortisone.

Other Discount Programs

Additional programs worth checking:

  • Optum Perks — free coupons for many medications
  • BuzzRx — discount card accepted at most pharmacies
  • ScriptSave WellRx — another widely accepted discount option
  • America's Pharmacy — may offer competitive pricing

Pro tip: Always compare prices across multiple discount cards. Prices can vary significantly between programs and between pharmacies, even for the same medication.

Patient Assistance Programs

If you're uninsured or underinsured and struggling to afford your medication, patient assistance programs (PAPs) may help:

Novartis Patient Assistance Foundation

Since Cipro HC is a Novartis product, the Novartis Patient Assistance Foundation (PAF) may provide the brand medication at no cost to qualifying patients. Eligibility typically requires:

  • U.S. residency
  • No prescription drug coverage (or inadequate coverage)
  • Income below certain thresholds

Contact Novartis PAF directly or visit their website to check eligibility and apply.

NeedyMeds

NeedyMeds is a comprehensive database of patient assistance programs, discount drug cards, and disease-based assistance funds. Search for Ciprofloxacin/Hydrocortisone to see all available programs.

RxAssist

RxAssist maintains a directory of pharmaceutical company patient assistance programs and other resources for affordable medications.

RxHope

RxHope helps connect patients with manufacturer-sponsored assistance programs through a simple online application process.

Other Ways to Save

Ask About Alternatives

If Ciprofloxacin/Hydrocortisone is still too expensive, even as a generic, talk to your doctor about more affordable alternatives:

  • Cortisporin (Neomycin/Polymyxin B/Hydrocortisone): $15 to $30 — the most affordable antibiotic + steroid ear drop option
  • Ofloxacin 0.3% otic: $25 to $40 — a fluoroquinolone without the steroid component
  • Ciprodex generic (Ciprofloxacin/Dexamethasone): $55 to $65 with coupon — closest therapeutic match

For a full comparison of alternatives, visit our guide on alternatives to Ciprofloxacin/Hydrocortisone.

Check Your Insurance Benefits

If you have insurance, call your plan's pharmacy benefit number (on the back of your insurance card) and ask:

  • Is Ciprofloxacin/Hydrocortisone on my formulary?
  • Is the generic covered?
  • What's my expected copay?
  • Do I need prior authorization?

Many insurance plans are adding the generic to their preferred tier in 2026, which could mean copays as low as $10 to $30.

Compare Prices Across Pharmacies

Prices for the same medication can vary dramatically between pharmacies — sometimes by $100 or more. Always check at least 3-4 pharmacies before filling your prescription. Tools like Medfinder, GoodRx, and SingleCare make this comparison easy.

Consider Mail-Order Pharmacy

If your ear infection isn't urgent, a mail-order pharmacy through your insurance plan may offer lower costs — especially for brand-name medications. Some plans offer 90-day supplies at reduced copays (though a 7-day course of ear drops typically doesn't warrant a 90-day supply, the overall cost structure may still be favorable).

A Quick Savings Cheat Sheet

  • Cheapest option: Generic Ciprofloxacin/Hydrocortisone with a discount coupon — estimated under $100
  • Best coupon for brand: SingleCare — as low as $130
  • If uninsured: Check NeedyMeds, RxAssist, and Novartis PAF for free or reduced-cost programs
  • If cost is the top priority: Ask your doctor about Cortisporin ($15-$30) or Ofloxacin otic ($25-$40)

Final Thoughts

Ciprofloxacin/Hydrocortisone doesn't have to break the bank. The launch of the first generic in December 2025 has already made this medication significantly more affordable, and prices should continue to decrease throughout 2026 as the generic becomes more widely available.

Start by asking your pharmacist for the generic. Then compare prices using discount cards. And if cost is still a barrier, talk to your doctor about equally effective alternatives that may be easier on your wallet.

For help finding Ciprofloxacin/Hydrocortisone in stock at a pharmacy near you, visit Medfinder.

How much does Ciprofloxacin/Hydrocortisone cost without insurance in 2026?

Brand-name Cipro HC Otic costs $350 to $480 per 10 mL bottle without insurance. The new generic by Cosette Pharmaceuticals (launched December 2025) is estimated at $70 to $150. With discount coupons like SingleCare, the brand can be as low as $130.

What is the cheapest way to get Ciprofloxacin/Hydrocortisone?

Ask for the generic version and use a discount card like GoodRx, SingleCare, or RxSaver. The generic is estimated at $70 to $150 per bottle, and coupons may reduce this further. If cost is still too high, ask your doctor about Cortisporin ($15-$30) or Ofloxacin otic ($25-$40) as more affordable alternatives.

Are there patient assistance programs for Ciprofloxacin/Hydrocortisone?

Yes. The Novartis Patient Assistance Foundation may provide brand Cipro HC at no cost to qualifying uninsured or underinsured patients. NeedyMeds, RxAssist, and RxHope also maintain directories of assistance programs that may help cover the cost.

Will my insurance cover the generic Ciprofloxacin/Hydrocortisone?

Most insurance plans are adding the generic to their formularies in 2026, typically on a preferred tier with copays ranging from $10 to $30. Call your insurance plan's pharmacy number to confirm coverage and check if prior authorization is required.

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