Dofetilide Shortage Update: What Patients Need to Know in 2026

The Dofetilide shortage that began in 2023 is still affecting patients in 2026. If you depend on this medication to control atrial fibrillation or atrial flutter, here's everything you need to know about the current state of the shortage, what it means for cost, and how to make sure you don't go without your medication.

Is Dofetilide Still in Shortage?

Yes. As of early 2026, Dofetilide capsules remain listed as a current drug shortage by the American Society of Health-System Pharmacists (ASHP). The shortage was first reported in April 2023 and has persisted for nearly three years.

Here's the current supply picture:

• Accord Healthcare — Discontinued Dofetilide capsules entirely
• Sun Pharmaceutical — Discontinued all three strengths (125 mcg, 250 mcg, 500 mcg)
• Novadoz — Has generic Dofetilide capsules available
• Pfizer (Tikosyn) — Brand name Tikosyn is available

With only two suppliers remaining in the market, any hiccup in production or distribution can cause localized outages at pharmacies — even though the medication is technically "available" at the manufacturer level.

Why Is Dofetilide Still Hard to Find?

The root cause hasn't changed: too few manufacturers making the product. When a drug market shrinks to just two suppliers, the supply chain becomes fragile. Additional factors include:

• Small patient population — Dofetilide is a niche cardiac medication prescribed mainly by electrophysiologists, making it less profitable to manufacture.
• Low pharmacy stocking rates — Many retail pharmacies don't routinely stock Dofetilide because they dispense it infrequently.
• Distribution bottlenecks — Even when manufacturers have supply, it may not reach every wholesaler or pharmacy equally.

What Does Dofetilide Cost in 2026?

Cost can vary significantly depending on whether you're getting the generic or the brand:

• Generic Dofetilide (retail cash price): Approximately $400–$530 for a 30-day supply (60 capsules) without insurance
• Generic Dofetilide (with discount coupon): As low as $18–$25 per month using savings cards from GoodRx or similar services
• Brand Tikosyn (retail cash price): Approximately $830+ for a 30-day supply without insurance

If cost is a concern, check out our full guide to saving money on Dofetilide for coupons, discount cards, and patient assistance program details.

Are There New Options for Patients?

While there are no new generic manufacturers entering the Dofetilide market as of early 2026, there are some developments worth noting:

• Discount coupons have dramatically reduced generic prices — Services like GoodRx can bring the generic cost down to under $25 per month, a major improvement over the retail price.
• Pfizer's patient assistance program continues — Pfizer RxPathways remains available for eligible patients who need help affording brand Tikosyn.
• Alternative medications remain available — If Dofetilide remains unavailable, your cardiologist has several alternative antiarrhythmic options to consider.

How to Find Dofetilide in Stock Right Now

Despite the shortage, Dofetilide can be found. Here's what works:

1. Search on Medfinder — Use Medfinder to find pharmacies with Dofetilide in stock near your zip code.
2. Ask for both generic and brand — Have your pharmacy check both Novadoz generic and Pfizer Tikosyn availability through their wholesalers.
3. Try independent pharmacies — They often have access to different wholesalers and may have better luck sourcing shortage medications.
4. Refill early and ask for partial fills — Don't wait until you're out. If the pharmacy has some capsules but not a full 30-day supply, a partial fill can bridge the gap.
5. Contact your cardiologist's office — They deal with Dofetilide supply issues regularly and may know which local pharmacies have stock.

Final Thoughts

The Dofetilide shortage is now entering its third year, and there's no clear timeline for a return to full supply. The most important thing you can do is stay proactive: refill early, use tools to find pharmacies with stock, and stay in close contact with your cardiologist. Don't let a supply disruption interrupt your treatment — help is available.

Need to find Dofetilide now? Check availability near you on Medfinder.