Alternatives to Loestrin Fe 1/20 28 Day If You Can't Fill Your Prescription

Updated:

February 27, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Can't fill your Loestrin Fe 1/20 28 Day prescription? Here are proven alternatives with the same ingredients and similar options to discuss with your doctor.

When Your Loestrin Fe 1/20 28 Day Prescription Can't Be Filled

There's nothing more frustrating than being told your birth control is unavailable — especially when you need to take it every day. If you've been unable to fill your Loestrin Fe 1/20 28 Day prescription, you're not alone. Supply issues have affected this medication and its generics on and off since 2023.

The good news is that there are several alternatives that work the same way and contain the same (or very similar) active ingredients. Let's walk through what Loestrin Fe 1/20 28 Day is, how it works, and which alternatives might be right for you.

What Is Loestrin Fe 1/20 28 Day?

Loestrin Fe 1/20 28 Day is a combination oral contraceptive — a daily birth control pill. Each pack contains:

  • 21 white active tablets with norethindrone acetate (1 mg) and ethinyl estradiol (20 mcg)
  • 7 brown tablets with ferrous fumarate (75 mg of iron)

The "Fe" in the name stands for iron — the brown tablets help supplement your iron intake during your period week. The "1/20" refers to the hormone doses: 1 mg of norethindrone acetate and 20 mcg of ethinyl estradiol.

For a complete overview, see our post: What is Loestrin Fe 1/20 28 Day?

How Does Loestrin Fe 1/20 28 Day Work?

Loestrin Fe 1/20 28 Day prevents pregnancy through three mechanisms:

  1. Prevents ovulation: The combination of estrogen and progestin stops your ovaries from releasing an egg each month.
  2. Thickens cervical mucus: This makes it harder for sperm to reach an egg.
  3. Thins the uterine lining: This reduces the chance of a fertilized egg implanting.

Want to learn more? Read our detailed article: How does Loestrin Fe 1/20 28 Day work?

Alternatives to Loestrin Fe 1/20 28 Day

Below are the best alternatives, starting with identical generics and then moving to similar options. Always talk to your doctor before switching medications.

1. Junel Fe 1/20

Junel Fe 1/20 is one of the most commonly dispensed generic equivalents of Loestrin Fe 1/20. It contains the exact same active ingredients at the exact same doses:

  • Norethindrone acetate 1 mg
  • Ethinyl estradiol 20 mcg
  • Ferrous fumarate 75 mg (iron tablets)

Why consider it: It's therapeutically identical to Loestrin Fe 1/20. If your pharmacy has Junel Fe 1/20 in stock but not your current generic, this is a straightforward swap. The cash price with a discount card is typically $9-$25 per pack.

2. Microgestin Fe 1/20

Microgestin Fe 1/20 is another popular generic version of Loestrin Fe 1/20 with identical active ingredients and dosing. It's been on the market for years and is widely available.

Why consider it: Like Junel Fe, it's the same medication under a different generic name. Many pharmacies stock Microgestin even when other generics are unavailable. Pricing with discount cards ranges from $10-$30 per pack.

3. Blisovi Fe 1/20

Blisovi Fe 1/20 is a newer generic equivalent that has gained popularity. Same active ingredients, same doses, same 28-day regimen.

Why consider it: Because it entered the market more recently, some pharmacies may have better stock levels. It's another one-to-one substitute that your pharmacist should be able to dispense without a new prescription (if your Rx allows generic substitution).

4. Lo Loestrin Fe

Lo Loestrin Fe is not a direct generic equivalent — it's a different formulation with a lower estrogen dose. It contains:

  • Norethindrone acetate 1 mg
  • Ethinyl estradiol 10 mcg (half the estrogen in Loestrin Fe 1/20)
  • 26 active tablets + 2 estrogen-only tablets + 2 iron tablets

Why consider it: If you've experienced estrogen-related side effects like headaches, bloating, or breast tenderness with Loestrin Fe 1/20, Lo Loestrin Fe may be a good option. It requires a new prescription since it's a different product. Cash prices are higher (around $150-$200 per pack for brand), but manufacturer savings cards may be available.

Other Options Worth Discussing

If none of the above are available, your doctor might consider:

  • Larin Fe 1/20 — Another identical generic
  • Gildess Fe 1/20 — Same active ingredients
  • Hailey Fe 1/20 — Same formulation, different manufacturer
  • Minastrin 24 Fe — A chewable version with 24 active pills + 4 iron pills (slightly different regimen)

How to Switch Safely

If you're switching between identical generics (Junel Fe 1/20, Microgestin Fe 1/20, Blisovi Fe 1/20, etc.), the transition is usually seamless — just finish your current pack and start the new one. For different formulations like Lo Loestrin Fe or Minastrin 24 Fe, follow your doctor's specific instructions about when and how to start.

Need help finding any of these alternatives in stock? Use Medfinder to check availability at pharmacies near you. You can also read our tips on how to find Loestrin Fe 1/20 28 Day in stock.

Final Thoughts

Running out of birth control options is stressful, but you have more alternatives than you might think. Several generics contain the exact same hormones as Loestrin Fe 1/20 28 Day, and even if those are hard to find, lower-dose options like Lo Loestrin Fe may work well for you.

Talk to your doctor or a telehealth provider about which alternative is best, and use Medfinder to find it in stock near you. You shouldn't have to go without your birth control because of a supply chain problem.

Are generic versions of Loestrin Fe 1/20 28 Day the same as the brand?

Yes. Generics like Junel Fe 1/20, Microgestin Fe 1/20, and Blisovi Fe 1/20 contain the same active ingredients (norethindrone acetate 1 mg and ethinyl estradiol 20 mcg) at the same doses. The FDA requires generics to be bioequivalent to the brand-name drug.

Can I switch between generics of Loestrin Fe 1/20 without side effects?

Most women can switch between identical generics without any issues. The active ingredients are the same. However, inactive ingredients (fillers, dyes) differ slightly between brands, so some women notice minor differences. If you have concerns, talk to your doctor.

What is the cheapest alternative to Loestrin Fe 1/20 28 Day?

Generic equivalents like Junel Fe 1/20 and Microgestin Fe 1/20 are the cheapest options, costing as low as $9-$14 per pack with a discount card like SingleCare or GoodRx. Under the ACA contraceptive mandate, many insurance plans cover generics with a $0 copay.

Do I need a new prescription to switch to a Loestrin Fe 1/20 alternative?

Not if you're switching to another AB-rated generic (like Junel Fe 1/20 to Microgestin Fe 1/20) — your pharmacist can usually make this substitution. If you're switching to a different formulation like Lo Loestrin Fe or Minastrin 24 Fe, you will need a new prescription from your doctor.

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