Comprehensive medication guide to Chorionic Gonadotropin including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$30–$100/month
Estimated Cash Pricing
$266–$465/month
Medfinder Findability Score
35/100
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Chorionic Gonadotropin (HCG) is a naturally occurring hormone that is produced during pregnancy. The pharmaceutical version is classified as a gonadotropin and is used for several important medical purposes. In women, it is used to trigger ovulation as part of fertility treatments, including in vitro fertilization (IVF). In men, it treats hypogonadotropic hypogonadism by stimulating the testes to produce testosterone. It is also used in prepubertal boys with cryptorchidism (undescended testicles) to promote testicular descent.
HCG is commonly used off-label as an adjunct to testosterone replacement therapy (TRT) to help maintain testicular size and preserve fertility. It is available as FDA-approved brand-name products including Pregnyl (Organon), Novarel (Ferring Pharmaceuticals), and Ovidrel (EMD Serono, recombinant form), as well as generic versions.
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5,000 USP units
Powder for injection (lyophilized) with bacteriostatic water diluent (generic)
10,000 USP units
Powder for injection with bacteriostatic water diluent (Pregnyl, Novarel, generic)
Ovidrel 250 mcg/0.5 mL
Prefilled syringe for subcutaneous injection (recombinant choriogonadotropin alfa)
Serious side effects that require immediate medical attention include ovarian hyperstimulation syndrome (OHSS), thromboembolism (blood clots), severe allergic reactions, and ovarian torsion or rupture. OHSS can be life-threatening and is a particular risk when HCG is used for fertility treatment. Contact your healthcare provider immediately if you experience severe abdominal pain, rapid weight gain, difficulty breathing, or signs of blood clots.
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Ovidrel (Choriogonadotropin Alfa)
A recombinant form of HCG for ovulation triggering; available as a prefilled syringe for subcutaneous injection with more consistent potency
Leuprolide (Lupron) as trigger
A GnRH agonist used as an alternative trigger shot in IVF to reduce the risk of ovarian hyperstimulation syndrome (OHSS); not interchangeable with HCG in all clinical scenarios
Menotropins (Menopur)
Contains both FSH and LH activity; used for ovarian stimulation in fertility treatment as part of the gonadotropin class
Clomiphene Citrate (Clomid)
An oral ovulation-inducing agent used for similar fertility goals in less complex protocols; not a gonadotropin but a more accessible first-line option
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GnRH antagonists (e.g., Ganirelix)
moderateMay interfere with HCG efficacy if timing is not carefully coordinated during fertility treatment protocols
Androgens (testosterone and related compounds)
moderateConcurrent use may increase the risk of edema and fluid retention
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