Struggling to find Ibrexafungerp (Brexafemme)? Learn why this antifungal is so hard to find in 2026, what's causing limited availability, and what you can do.
You finally got a prescription for Ibrexafungerp — sold under the brand name Brexafemme — and now your pharmacy is telling you they don't have it in stock. You call another pharmacy. Same answer. It can feel incredibly frustrating, especially when you're dealing with the discomfort of a vaginal yeast infection.
You're not imagining it: Ibrexafungerp really can be hard to find. But understanding why can help you figure out what to do next. In this article, we'll break down the reasons Brexafemme is difficult to locate at pharmacies in 2026 and share practical steps you can take to get your medication.
Ibrexafungerp (brand name: Brexafemme) is a prescription antifungal medication made by Scynexis, Inc. It was approved by the FDA in June 2021 and is the first non-azole oral antifungal ever approved for vaginal yeast infections.
It works by blocking an enzyme called glucan synthase, which fungi need to build their cell walls. Without it, the fungal cells break down and die. Ibrexafungerp is approved for two uses:
For more details on what this drug is and how it works, check out our guides on what Ibrexafungerp is and how Ibrexafungerp works.
There are several reasons why Brexafemme can be difficult to locate at your local pharmacy. Here are the main ones:
Unlike Fluconazole (Diflucan), which has been available as a cheap generic for years, Ibrexafungerp has no generic version. It's only made by one company — Scynexis. That means the entire supply depends on a single manufacturer. If production slows or demand increases, availability tightens quickly.
Most retail pharmacies stock medications based on demand. Because Ibrexafungerp is relatively new and prescribed far less frequently than Fluconazole, many pharmacies simply don't keep it on their shelves. It's not that the drug is unavailable nationally — it's that your particular pharmacy may not have ordered it.
The cash price for a course of Brexafemme runs approximately $700 to $900 without insurance. That price tag means fewer patients fill the prescription, which in turn means pharmacies have less incentive to stock it. It's a cycle that keeps the drug hard to find at everyday pharmacies.
Many insurance plans require prior authorization or step therapy before they'll cover Brexafemme. Step therapy typically means you need to try (and fail) a cheaper drug like Fluconazole first. These hurdles mean fewer prescriptions are approved, further reducing pharmacy demand and stocking.
Want to learn more about managing costs? Read our guide on how to save money on Ibrexafungerp.
The good news is that Ibrexafungerp is available — you just may need to be a bit more resourceful in finding it. Here are some practical steps:
Medfinder helps you search for pharmacies that have specific medications in stock near you. Instead of calling pharmacy after pharmacy, you can check availability in real time.
Big chain pharmacies may not stock Brexafemme, but independent pharmacies and specialty pharmacies are often more flexible about ordering less common medications. They may be able to have it ready for you within a day or two.
Your prescriber's office may know which pharmacies in the area commonly fill Brexafemme prescriptions. They may also be able to send the prescription to a pharmacy that stocks it or help with prior authorization paperwork.
Some mail-order and specialty pharmacies carry Brexafemme and can ship it directly to you. This can be especially convenient if no local pharmacies stock it.
For a more detailed walkthrough, check out our guide on how to find Ibrexafungerp in stock near you.
If you've exhausted your options and still can't locate Brexafemme, talk to your doctor about alternatives to Ibrexafungerp. Depending on your situation, options like Fluconazole, Miconazole, Clotrimazole, or Terconazole may be appropriate. Your doctor can determine the best next step based on your medical history and the type of yeast infection you have.
Ibrexafungerp (Brexafemme) is an important medication — it's the only non-azole oral treatment for vaginal yeast infections. But because it's a newer, single-source brand-name drug with a high price tag, finding it at your local pharmacy can be a challenge in 2026.
The key is to not give up. Use tools like Medfinder, explore independent pharmacies, and work with your doctor to find a path to the treatment you need.
You focus on staying healthy. We'll handle the rest.
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