Phenobarbital shortage update: What patients need to know in 2026

Updated:

February 24, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Get the latest Phenobarbital shortage update for 2026. Learn about current supply status, what's causing availability issues, and what patients can do.

Phenobarbital Shortage Update: What Patients Need to Know in 2026

If you take Phenobarbital for seizures, epilepsy, or another condition, you may have noticed it's been harder to find at pharmacies lately. Supply problems with essential medications are stressful — especially when missing doses can have serious health consequences. Here's everything patients need to know about the Phenobarbital supply situation in 2026.

Current Phenobarbital Supply Status (February 2026)

As of early 2026, Phenobarbital oral tablets are not formally listed on the FDA's active drug shortage list. However, this doesn't mean every pharmacy has it in stock. Many patients report difficulty finding specific strengths or quantities, particularly:

  • Higher-strength tablets (60 mg, 97.2 mg, 100 mg)
  • The oral elixir (liquid) formulation
  • Injectable formulations (used primarily in hospitals)

The situation can vary significantly by region. Pharmacies in some areas may have plenty of Phenobarbital, while others experience weeks-long gaps in availability.

What's Causing the Supply Issues?

Several factors contribute to Phenobarbital availability problems:

Limited Manufacturers

Phenobarbital is a very old, low-cost generic medication. Only a handful of companies still manufacture it in the United States. When even one manufacturer experiences a disruption — whether from a facility issue, regulatory inspection, or raw material shortage — it can ripple across the entire market.

DEA Production Quotas

As a Schedule IV controlled substance, Phenobarbital production is subject to DEA manufacturing quotas that cap how much can be made each year. These quotas are designed to prevent diversion and misuse but can limit supply flexibility when demand spikes.

Shared Demand with Veterinary Use

Phenobarbital is one of the most commonly prescribed medications for seizures in dogs and cats. Human and veterinary formulations can draw from the same supply chain, adding competition for limited stock.

Supply Chain Disruptions

Global supply chain challenges — including active pharmaceutical ingredient (API) sourcing from overseas manufacturers — continue to affect medication availability across many drug classes.

A Brief History of Phenobarbital Shortages

Phenobarbital supply issues are not new. The injectable formulation has been on and off the FDA shortage list several times over the past decade. Oral tablet shortages have been less common but have occurred periodically, particularly when a manufacturer temporarily exits the market or faces production delays.

What You Can Do Right Now

1. Search for Availability

Use MedFinder to check which pharmacies near you currently have Phenobarbital in stock. This is the fastest way to avoid calling pharmacy after pharmacy. For a complete search strategy, see How to Find Phenobarbital in Stock Near You.

2. Talk to Your Pharmacist

Your pharmacist may be able to order Phenobarbital from a different wholesaler or suggest an alternative strength that's available. Don't hesitate to ask — pharmacists deal with supply issues daily and may have solutions you haven't considered. See How to Check If a Pharmacy Has Phenobarbital in Stock.

3. Contact Your Doctor

Let your prescriber know you're having trouble finding Phenobarbital. They can:

  • Send the prescription to a pharmacy that has it in stock
  • Adjust your prescription to a strength or formulation that's available
  • Discuss temporary or permanent alternative medications if needed

4. Plan Ahead

Request refills as early as your insurance allows. If you're on a 30-day supply, ask about switching to a 90-day supply to reduce the frequency of refills and give you a larger buffer.

5. Never Stop Suddenly

This cannot be stressed enough: do not stop taking Phenobarbital abruptly. Sudden discontinuation can trigger dangerous withdrawal symptoms, including seizures that can be life-threatening. If you're running out and can't find more, contact your doctor immediately for guidance.

How to Stay Informed

Stay up to date on Phenobarbital availability:

  • FDA Drug Shortage Database: Check FDA.gov for official shortage listings
  • ASHP Drug Shortage Resource: The American Society of Health-System Pharmacists maintains a shortage tracking database
  • MedFinder: medfinder.com for real-time pharmacy availability
  • Your pharmacist: They often know about supply changes before official databases are updated

Understanding Your Options

Whether the supply situation improves or worsens, it's good to understand all your options:

The Bottom Line

While Phenobarbital isn't in a formal nationwide shortage as of early 2026, many patients are still finding it difficult to locate at their local pharmacies. The combination of limited manufacturers, controlled substance regulations, and supply chain factors means you need to be proactive about your medication supply. Use MedFinder to find Phenobarbital in stock near you, and stay in close communication with your doctor and pharmacist.

Is Phenobarbital currently in shortage in 2026?

As of February 2026, Phenobarbital oral tablets are not formally listed on the FDA's active drug shortage database. However, many patients report difficulty finding certain strengths at local pharmacies. The injectable formulation has faced more significant supply issues historically.

How long will the Phenobarbital shortage last?

There is no specific timeline for when all Phenobarbital supply issues will be fully resolved. The situation depends on manufacturer production capacity, DEA quotas, and raw material availability. Check MedFinder regularly for current availability in your area.

Can my doctor prescribe a larger supply to help me during the shortage?

Possibly. Many doctors will prescribe a 90-day supply instead of a 30-day supply to reduce the frequency of refills. However, as a controlled substance, there may be insurance or state limitations on quantity. Discuss this option with your doctor and pharmacist.

What happens if I miss doses of Phenobarbital due to the shortage?

Missing doses of Phenobarbital can increase your risk of seizures and may cause withdrawal symptoms like anxiety, tremors, and insomnia. If you're at risk of running out, contact your doctor immediately. They can help you find Phenobarbital or safely transition to an alternative medication.

Why waste time calling, coordinating, and hunting?

You focus on staying healthy. We'll handle the rest.

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