How to Help Your Patients Save Money on Gomekli: A Provider's Guide to Savings Programs

Gomekli (mirdametinib) is a high-cost specialty medication — a reality that can create significant barriers for NF1-PN patients who need it. As a provider prescribing Gomekli, understanding the full landscape of financial assistance programs and knowing how to connect your patients with them is just as important as the clinical decision to prescribe. This guide walks through all available programs and provides practical guidance on helping your patients access them.

Understanding the Cost Landscape for Gomekli

Gomekli is a brand-name specialty drug with no generic equivalent. The list price reflects the significant investment required to develop a targeted therapy for a rare disease, and the annual cost of treatment can exceed $100,000 without financial assistance. For context, a 21-day supply of Gomekli capsules can cost thousands of dollars out-of-pocket.

However, the drug's manufacturer — SpringWorks Therapeutics — has invested significantly in patient access programs. When properly utilized, these programs can reduce patient out-of-pocket costs to $0 for commercially insured patients, and provide the medication at no cost for eligible uninsured or underinsured patients. Knowing these programs inside and out is essential for every provider who prescribes Gomekli.

Program 1: SpringWorks CareConnections Commercial Copay Program

The most powerful financial tool for commercially insured patients is the SpringWorks CareConnections Commercial Copay Program:

Benefit: Eligible patients with commercial insurance may pay as little as $0 per 21-day supply of Gomekli.

Eligibility: Commercially insured patients with coverage for Gomekli. Not available to government-insured patients (Medicare, Medicaid, TRICARE, etc.).

Additional benefits: May also reimburse eligible out-of-pocket costs for treatment-related tests, exams, and specialty visits during Gomekli treatment.

How to enroll: Patient self-enrollment is available at gomeklicopay.com. Providers can enroll patients by submitting the CareConnections enrollment form at springworkstxcares.com or by calling 844-CARES-55 (844-227-3755).

Timing: Enroll patients at the time of prescribing — do not wait until after PA approval.

Program 2: Patient Assistance Program (PAP)

For patients who are uninsured, underinsured, or who lack coverage for Gomekli, the SpringWorks CareConnections PAP may provide Gomekli at no cost:

Eligibility: Uninsured or underinsured patients meeting income criteria (annual household income limits apply).

Benefit: Gomekli at no cost for qualifying patients.

How to access: Contact SpringWorks CareConnections at 844-227-3755 or visit springworkstxcares.com. A Nurse Advocate will guide the enrollment process.

Program 3: Bridge Supply for Coverage Delays

Coverage delays are common for newly approved specialty drugs. CareConnections provides two types of bridge support:

New start bridge: Eligible patients experiencing delays in initial insurance approval can receive Gomekli at no cost temporarily while the PA is processed.

Coverage lapse bridge: Eligible patients already on Gomekli who experience a qualified lapse in insurance coverage may also qualify for temporary free supply.

For patients facing urgent clinical situations, bridge supply can be critical to preventing treatment gaps that could result in tumor regrowth. Inquire about bridge supply eligibility for every new Gomekli patient at enrollment.

Navigating Government Payer Coverage

Government-insured patients (Medicare, Medicaid, TRICARE) are not eligible for the commercial copay program, but coverage assistance is still available:

Medicare Part D: Gomekli may be covered as a Part D specialty drug. PA is required. Low-income subsidy (LIS/Extra Help) may reduce cost-sharing for eligible Medicare patients.

Medicaid: Coverage varies by state. CareConnections can provide state-specific Medicaid coverage guidance.

Independent foundations: Independent patient assistance foundations may offer additional support for government-insured patients with high cost-sharing. CareConnections can provide a list of relevant foundations.

The CareConnections Benefits Investigation: Your Starting Point

Before writing the first prescription, initiate a benefits investigation through CareConnections. This free service will quickly identify:

Whether the patient's plan covers Gomekli

The patient's expected out-of-pocket cost (before assistance programs)

Which specialty pharmacy is in-network for the patient's plan

PA requirements for the patient's specific insurance plan

Financial assistance program eligibility

How medfinder Supports Your Practice

medfinder for providers calls specialty pharmacies on your patients' behalf to identify which ones can fill their Gomekli prescription right now. This eliminates the burden on your office staff of making multiple calls to pharmacies, and ensures patients are connected with an available dispenser quickly — which is especially important when time is critical and bridge supply has run out.

For a complete step-by-step guide to the Gomekli access and prescribing process, see our companion article on how to help your patients find Gomekli in stock.