How to Find a Doctor Who Can Prescribe Entrectinib Near You [2026 Guide]

Entrectinib (Rozlytrek) is a prescription oncology medication that can only be prescribed by — or in consultation with — an oncologist who has confirmed the right biomarker profile through molecular testing. If you or a loved one may be a candidate, here's how to find the right specialist and navigate the process.

Who Can Prescribe Entrectinib?

Most insurance plans require that entrectinib be prescribed by a physician specializing in oncology, or in consultation with one. In practice, entrectinib is prescribed by:

Medical oncologists — the most common prescribers for ROS1-positive NSCLC and NTRK fusion-positive solid tumors

Thoracic oncologists — specialists in lung cancers, highly experienced with ROS1-positive NSCLC

Pediatric oncologists — for patients under 18 years old with NTRK fusion-positive solid tumors

Hematologist-oncologists — in cases where the NTRK-positive tumor is of hematologic origin

Primary care physicians and general practitioners cannot prescribe entrectinib independently. However, a PCP can refer you to an oncologist and order initial molecular testing if appropriate.

Why Biomarker Testing Comes First

Before any oncologist can prescribe entrectinib, your tumor must be tested with an FDA-approved molecular test to confirm either a ROS1 gene rearrangement (for lung cancer patients) or an NTRK1/2/3 gene fusion (for solid tumor patients). This is a non-negotiable step — insurers require documented test results for prior authorization, and the drug has no benefit for tumors without these specific genetic alterations.

Common testing methods include comprehensive next-generation sequencing (NGS) panels, which can detect multiple actionable mutations in one test. Testing is typically performed on tumor tissue from a biopsy or surgical specimen, or via liquid biopsy (blood test) when tissue is not available.

How to Find an Oncologist Near You

Ask your primary care physician for a referral. This is the most common path. Your PCP can refer you to a medical or thoracic oncologist within your insurance network.

Search the ASCO Find an Oncologist directory. The American Society of Clinical Oncology (ASCO) maintains a searchable directory of oncologists at asco.org/findanoncologist.

Contact an NCI-designated cancer center. NCI-designated comprehensive cancer centers have the deepest molecular tumor board expertise and the most experience with rare biomarker-positive cancers like ROS1+ NSCLC and NTRK+ tumors. The NCI lists all 71 centers at cancer.gov/research/infrastructure/cancer-centers.

Check your insurance directory. Your insurer's online provider directory will show you which oncologists are in-network. Filter for "oncology" or "hematology/oncology."

Is Telehealth an Option for Entrectinib?

Telehealth oncology is available at many major cancer centers and some community oncology practices. However, entrectinib requires physical examination, biomarker testing on tumor tissue, and ongoing lab monitoring that cannot be done remotely. Telehealth is most useful for follow-up consultations, ongoing monitoring visits, and getting a second opinion — not for initiating cancer therapy for the first time.

Some patients with ROS1+ or NTRK+ cancers use telehealth at major cancer centers for second opinions, particularly if they live far from a major cancer center. Organizations like Memorial Sloan Kettering, MD Anderson, Mayo Clinic, and others offer remote second-opinion consultations.

What to Bring to Your First Oncology Appointment

Pathology report from biopsy or tumor specimen

Any molecular or genetic test results already completed

Imaging reports (CT scan, PET scan, MRI) showing disease extent and staging

List of all current medications, supplements, and prior cancer treatments

Insurance information and any questions written down in advance

The Bottom Line

Getting a prescription for entrectinib starts with finding the right oncologist and completing biomarker testing. Once you have a prescription, medfinder can help you find a specialty pharmacy that can fill it near you. For more on what entrectinib treats and how it works, see our complete guide to entrectinib uses and dosage.