Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Veozah (Fezolinetant) is a prescription medication approved by the FDA for the treatment of moderate to severe vasomotor symptoms (VMS) — commonly known as hot flashes and night sweats — caused by menopause. It belongs to a new class of drugs called neurokinin 3 (NK3) receptor antagonists, offering a nonhormonal option for women who cannot or prefer not to use hormone replacement therapy (HRT).
Veozah is manufactured by Astellas Pharma and is taken as a once-daily 45 mg oral tablet. Unlike older treatments for hot flashes, Veozah works directly on the brain's temperature control center without affecting estrogen levels, making it a compelling option for women with contraindications to hormonal therapies.
Veozah works by selectively blocking the neurokinin 3 (NK3) receptor in the hypothalamus — the part of the brain that regulates body temperature. During menopause, declining estrogen levels cause an imbalance between estrogen and a brain chemical called neurokinin B (NKB). This imbalance makes the brain's thermostat overreact, triggering hot flashes and night sweats.
By blocking the NK3 receptor, Fezolinetant prevents NKB from activating the temperature control center, effectively restoring the thermostat's normal function and reducing the frequency and severity of vasomotor symptoms — all without introducing hormones into the body.
Veozah scores a 55 out of 100 on our findability scale, meaning it can be intermittently difficult to locate at your local pharmacy. As a newer brand-name medication manufactured solely by Astellas Pharma, not every pharmacy routinely stocks it. While there is no active FDA shortage, the relatively niche patient population and high price point mean some pharmacies may not carry it or may need to special-order it from their wholesaler.
If your pharmacy doesn't have Veozah in stock, ask them to order it directly — most can get it within 1–2 business days. You can also try calling larger chain pharmacies or specialty pharmacies in your area. Medfinder can help you locate pharmacies with Veozah available near you.
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Veozah can be prescribed by several types of healthcare providers, including:
Telehealth consultations are also available for Veozah prescriptions, making it easier to access this medication without an in-person visit. Medfinder can help you find providers who prescribe Veozah in your area.
No, Veozah is not a controlled substance. It is not scheduled by the DEA and does not carry risks of dependence or abuse. However, Veozah does carry a boxed warning for hepatotoxicity (liver injury), which means your doctor will need to order liver function tests before starting treatment and at regular intervals (months 1, 2, 3, 6, and 9) during treatment. This monitoring is mandatory — not optional.
Most side effects of Veozah are mild to moderate. Common side effects include:
Serious side effect — Liver injury (hepatotoxicity): Veozah carries a boxed warning for the risk of serious liver damage. Symptoms to watch for include fatigue, nausea, vomiting, itching, yellowing of the skin or eyes (jaundice), dark urine, pale stools, or pain in the upper right abdomen. If you experience any of these, stop taking Veozah immediately and contact your doctor.
If Veozah isn't the right fit — whether due to cost, liver concerns, or availability — there are several alternatives for managing menopausal hot flashes:
Veozah is metabolized by the CYP1A2 enzyme, which means drugs that inhibit this enzyme can significantly increase Veozah blood levels and the risk of side effects, especially liver injury.
Veozah represents a meaningful advance in nonhormonal treatment for menopausal hot flashes, offering women a once-daily option that works directly on the brain's temperature regulation without affecting estrogen levels. However, the boxed warning for liver injury and required liver monitoring make it important to work closely with your healthcare provider throughout treatment.
At $550–$765 per month without insurance, cost can be a significant barrier — but the Veozah Savings Card can reduce costs to as little as $30/month for commercially insured patients. If you're having trouble finding Veozah at your pharmacy, Medfinder can help you locate pharmacies that have it in stock near you.
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