Comprehensive medication guide to Veozah including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
With commercial insurance, eligible patients may pay as little as $0 for the first month and $30 per refill using the Veozah Savings Card.
Estimated Cash Pricing
Veozah costs approximately $550 to $765 per month without insurance for a 30-day supply of 45 mg tablets.
Medfinder Findability Score
55/100
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Veozah (Fezolinetant) is a prescription medication approved by the FDA for the treatment of moderate to severe vasomotor symptoms (VMS) — commonly known as hot flashes and night sweats — caused by menopause. It belongs to a new class of drugs called neurokinin 3 (NK3) receptor antagonists, offering a nonhormonal option for women who cannot or prefer not to use hormone replacement therapy (HRT).
Veozah is manufactured by Astellas Pharma and is taken as a once-daily 45 mg oral tablet. Unlike older treatments for hot flashes, Veozah works directly on the brain's temperature control center without affecting estrogen levels, making it a compelling option for women with contraindications to hormonal therapies.
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Veozah works by selectively blocking the neurokinin 3 (NK3) receptor in the hypothalamus — the part of the brain that regulates body temperature. During menopause, declining estrogen levels cause an imbalance between estrogen and a brain chemical called neurokinin B (NKB). This imbalance makes the brain's thermostat overreact, triggering hot flashes and night sweats.
By blocking the NK3 receptor, Fezolinetant prevents NKB from activating the temperature control center, effectively restoring the thermostat's normal function and reducing the frequency and severity of vasomotor symptoms — all without introducing hormones into the body.
Veozah 45 mg oral tablet — tablet
light red, round, film-coated tablet debossed with the Astellas logo and "645." This is the only available dose. Take one tablet by mouth once daily, with or without food.
Veozah scores a 55 out of 100 on our findability scale, meaning it can be intermittently difficult to locate at your local pharmacy. As a newer brand-name medication manufactured solely by Astellas Pharma, not every pharmacy routinely stocks it. While there is no active FDA shortage, the relatively niche patient population and high price point mean some pharmacies may not carry it or may need to special-order it from their wholesaler.
If your pharmacy doesn't have Veozah in stock, ask them to order it directly — most can get it within 1–2 business days. You can also try calling larger chain pharmacies or specialty pharmacies in your area. Medfinder can help you locate pharmacies with Veozah available near you.
Veozah can be prescribed by several types of healthcare providers, including:
Telehealth consultations are also available for Veozah prescriptions, making it easier to access this medication without an in-person visit. Medfinder can help you find providers who prescribe Veozah in your area.
No, Veozah is not a controlled substance. It is not scheduled by the DEA and does not carry risks of dependence or abuse. However, Veozah does carry a boxed warning for hepatotoxicity (liver injury), which means your doctor will need to order liver function tests before starting treatment and at regular intervals (months 1, 2, 3, 6, and 9) during treatment. This monitoring is mandatory — not optional.
Most side effects of Veozah are mild to moderate. Common side effects include:
Serious side effect — Liver injury (hepatotoxicity): Veozah carries a boxed warning for the risk of serious liver damage. Symptoms to watch for include fatigue, nausea, vomiting, itching, yellowing of the skin or eyes (jaundice), dark urine, pale stools, or pain in the upper right abdomen. If you experience any of these, stop taking Veozah immediately and contact your doctor.
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Lynkuet (Elinzanetant)
A newer dual NK1/NK3 receptor antagonist by Bayer, FDA-approved in October 2025. Also nonhormonal and may additionally help with menopause-related insomnia.
Brisdelle (Paroxetine mesylate 7.5 mg)
The only other FDA-approved nonhormonal treatment for VMS. A low-dose SSRI that doesn't require liver monitoring but may cause drowsiness.
Hormone Replacement Therapy (HRT)
Estrogen-based therapies (oral, patch, gel) remain the most effective treatment for hot flashes. Not appropriate for women with a history of breast cancer or blood clots.
Off-label options
Effexor XR (Venlafaxine), Neurontin (Gabapentin), and Catapres (Clonidine) are sometimes used off-label when other treatments aren't suitable.
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Enoxacin, Methoxsalen, Mexiletine, Vemurafenib
moderateCYP1A2 inhibitors
Oral contraceptives
moderateAcyclovir, Allopurinol, Cimetidine
moderateZileuton, Peginterferon alpha-2a
moderateCaffeine
moderatemay increase Veozah blood levels. Limit coffee, tea, energy drinks, and chocolate.
Grapefruit
moderatepotential CYP interaction; consult your prescriber.
Veozah represents a meaningful advance in nonhormonal treatment for menopausal hot flashes, offering women a once-daily option that works directly on the brain's temperature regulation without affecting estrogen levels. However, the boxed warning for liver injury and required liver monitoring make it important to work closely with your healthcare provider throughout treatment.
At $550–$765 per month without insurance, cost can be a significant barrier — but the Veozah Savings Card can reduce costs to as little as $30/month for commercially insured patients. If you're having trouble finding Veozah at your pharmacy, Medfinder can help you locate pharmacies that have it in stock near you.
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