Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Hadlima (adalimumab-bwwd) is an FDA-approved biosimilar to Humira manufactured by Organon. It belongs to the class of TNF (tumor necrosis factor) blockers — biologic medications that target inflammation at its source. Hadlima is approved to treat a wide range of autoimmune and inflammatory conditions, including:
As a biosimilar, Hadlima has been shown to be highly similar to the reference product Humira with no clinically meaningful differences in safety, purity, or effectiveness.
Hadlima is a fully human monoclonal antibody that works by binding specifically to tumor necrosis factor-alpha (TNF-alpha), a protein in the body that drives inflammation. In autoimmune conditions, the immune system overproduces TNF-alpha, leading to chronic inflammation and tissue damage. By blocking TNF-alpha from attaching to cell surface receptors, Hadlima helps reduce inflammation, ease symptoms like joint pain and swelling, and slow disease progression. The medication is administered via subcutaneous injection, typically every other week, though some conditions require higher loading doses initially.
The 40 mg/0.4 mL citrate-free formulations are generally preferred by patients as they cause less injection site pain.
Hadlima scores a 40 out of 100 on our findability scale, meaning it can be difficult to locate at many pharmacies. As a newer adalimumab biosimilar that launched in July 2023, not all pharmacies routinely stock it. Many retail pharmacies still default to dispensing Humira, and formulary transitions are ongoing. Specialty pharmacies and mail-order services tend to have better availability. If your local pharmacy doesn't carry Hadlima, Medfinder can help you locate a pharmacy that has it in stock near you.
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Hadlima is most commonly prescribed by specialists who manage autoimmune and inflammatory diseases:
Because Hadlima requires prior authorization from most insurance plans and carries a boxed warning, it is almost always initiated by a specialist rather than a primary care physician.
No, Hadlima is not a controlled substance and is not scheduled by the DEA. It is a prescription biologic medication that requires a valid prescription from a licensed healthcare provider but does not have the prescribing restrictions associated with controlled substances.
Important: Hadlima carries a boxed warning for serious infections (including tuberculosis and invasive fungal infections) and an increased risk of lymphoma and other malignancies, particularly in children and adolescents. TB testing is required before starting treatment. Contact your doctor immediately if you develop fever, persistent cough, or signs of infection while taking Hadlima.
If you're unable to find Hadlima or it's not right for you, several alternatives are available:
All of these treat the same conditions and work through the same TNF-blocking mechanism. Your doctor and insurance plan will help determine which option provides the best balance of cost and availability for you. Use Medfinder to check availability of any of these alternatives.
Methotrexate is commonly used alongside Hadlima for rheumatoid arthritis and is generally considered safe in combination, though it may affect how the body clears adalimumab. Always inform your doctor of all medications you are taking.
Hadlima offers patients a significantly more affordable biosimilar alternative to Humira, with a wholesale acquisition cost of roughly $1,038 per carton compared to Humira's $6,922. However, because it's a relatively new biosimilar, finding it stocked at your local pharmacy can be challenging — many pharmacies still default to Humira or other more established options. Specialty pharmacies and mail-order services often have better Hadlima availability. If your insurance plan covers Hadlima (and many now prefer biosimilars), Organon's $0 co-pay card can bring your out-of-pocket cost down substantially. Use Medfinder to locate Hadlima in stock near you and save time calling pharmacies.
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