Medications

Benzonatate

Benzonatate

Previously Found with Medfinder

Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.

Estimated Insurance Pricing
$0–$15 copay; Tier 1 generic, typically covered without prior authorization
Estimated Cash Pricing
$10–$45 retail; as low as $4–$15 with GoodRx or SingleCare coupons
Medfinder Findability Score
82
/100
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Post Author

Peter Daggett

Last Updated

March 27, 2026

Benzonatate 2026 Availability, Prices, and Tips to Find

What Is Benzonatate?

Benzonatate is a non-narcotic antitussive (cough suppressant) used to relieve coughs caused by colds, bronchitis, pneumonia, and other respiratory conditions. It was first approved by the FDA in 1958 and has been a staple cough treatment for decades. Unlike opioid-based cough suppressants like codeine, Benzonatate is not a controlled substance and does not carry the same risk of addiction or respiratory depression.

The brand-name version is Tessalon Perles, though most prescriptions today are filled with the generic version, which is significantly more affordable.

How does Benzonatate work?

Benzonatate works by numbing (anesthetizing) the stretch receptors in the lungs and airways. These receptors are responsible for triggering the cough reflex. By reducing the sensitivity of these receptors, Benzonatate suppresses the urge to cough without affecting the central nervous system the way opioid cough suppressants do.

Chemically, Benzonatate is related to tetracaine, a local anesthetic. It typically begins working within 15 to 20 minutes after ingestion, and its effects last for 3 to 8 hours. The usual adult dose is 100 mg to 200 mg taken three times daily as needed.

What doses are available for Benzonatate?

  • 100 mg capsules — the most commonly prescribed strength
  • 150 mg capsules — less common but available from some manufacturers
  • 200 mg capsules — another standard dosage option

Benzonatate is available only as oral capsules (perles). There is no liquid, chewable, or extended-release formulation. Capsules must be swallowed whole — they should never be chewed or dissolved, as this can cause serious numbness of the mouth and throat.

How hard is it to find Benzonatate in stock?

Benzonatate is a widely available generic medication used to suppress coughs. It is stocked at most major retail and independent pharmacies across the United States. Occasional spot shortages may occur due to supply chain fluctuations, but overall availability is strong. If your local pharmacy is temporarily out, checking nearby pharmacies or using Medfinder can help you locate it quickly.

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Who Can Prescribe Benzonatate?

Benzonatate can be prescribed by a wide range of healthcare providers, including:

  • Primary care physicians — the most common prescribers for acute cough
  • Urgent care providers — frequently prescribed for colds and upper respiratory infections
  • Pulmonologists — for patients with chronic cough or underlying lung conditions
  • Nurse practitioners (NPs) and physician assistants (PAs) — commonly prescribe for respiratory symptoms
  • ENT specialists (Otolaryngologists) — for cough related to post-nasal drip or sinus conditions

Is Benzonatate a controlled substance?

No. Benzonatate is not classified as a controlled substance by the DEA. Unlike codeine-containing cough syrups, it does not have abuse potential or require special prescribing restrictions. A standard prescription is all that is needed, and refills are straightforward.

However, it is important to note that Benzonatate can be dangerous if misused — particularly if capsules are chewed or dissolved instead of swallowed whole, which can cause severe oropharyngeal numbing, choking, and in rare cases, fatal reactions, especially in children under 10 years of age.

Common Side Effects of Benzonatate

  • Drowsiness or sedation
  • Dizziness
  • Headache
  • Nausea
  • Constipation
  • Nasal congestion
  • Feeling of numbness in the chest (mild)
  • Skin rash or itching (rare)

Most side effects are mild and resolve on their own. Serious warning: If capsules are chewed or dissolved in the mouth, severe numbing of the throat can occur, potentially leading to choking or aspiration. Seek emergency medical attention if you experience difficulty breathing, severe allergic reactions, or confusion after taking Benzonatate.

Alternative Medications to Benzonatate

  • Dextromethorphan (DM) — available over-the-counter in many cough and cold products (e.g., Delsym, Robitussin DM)
  • Codeine/Guaifenesin — prescription cough syrup; codeine is a controlled substance
  • Hydrocodone/Homatropine — stronger prescription option for severe cough; controlled substance
  • Guaifenesin — an expectorant (not a suppressant) that helps thin mucus; available OTC (Mucinex)
  • Honey-based remedies — evidence supports honey as effective for nighttime cough in children over 1 year

If Benzonatate is unavailable or unsuitable, talk to your doctor about which alternative is best for your situation.

Drug Interactions with Benzonatate

  • CNS depressants (alcohol, benzodiazepines, opioids, sleep aids) — may increase drowsiness and sedation when combined with Benzonatate
  • Other local anesthetics — theoretical additive numbing effects; use caution
  • MAO inhibitors — potential for increased side effects; consult your doctor

Benzonatate has relatively few drug interactions compared to opioid-based cough suppressants. However, always inform your pharmacist and doctor of all medications you are taking, including over-the-counter products and supplements.

Final Thoughts on Benzonatate

Benzonatate remains one of the most widely prescribed non-narcotic cough suppressants in the United States. It is affordable, effective, and generally well-tolerated. As a generic medication, it is available at virtually every pharmacy and is covered by most insurance plans at low copays.

If you're having trouble finding Benzonatate in stock at your pharmacy, use Medfinder to search nearby locations with availability. With discount coupons from GoodRx or SingleCare, cash prices can be as low as $4–$15, making it one of the most affordable prescription cough medications on the market.

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