Comprehensive medication guide to Benzonatate including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$0–$15/month
Estimated Cash Pricing
$4–$45/month
Medfinder Findability Score
82/100
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Benzonatate is a non-narcotic antitussive (cough suppressant) used to relieve coughs caused by colds, bronchitis, pneumonia, and other respiratory conditions. It was first approved by the FDA in 1958 and has been a staple cough treatment for decades. Unlike opioid-based cough suppressants like codeine, Benzonatate is not a controlled substance and does not carry the same risk of addiction or respiratory depression.
The brand-name version is Tessalon Perles, though most prescriptions today are filled with the generic version, which is significantly more affordable.
100 mg capsules
the most commonly prescribed strength
150 mg capsules
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less common but available from some manufacturers
200 mg capsules
another standard dosage option
Most side effects are mild and resolve on their own. Serious warning: If capsules are chewed or dissolved in the mouth, severe numbing of the throat can occur, potentially leading to choking or aspiration. Seek emergency medical attention if you experience difficulty breathing, severe allergic reactions, or confusion after taking Benzonatate.
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Dextromethorphan (DM)
available over-the-counter in many cough and cold products (e.g., Delsym, Robitussin DM)
Codeine/Guaifenesin
prescription cough syrup; codeine is a controlled substance
Hydrocodone/Homatropine
stronger prescription option for severe cough; controlled substance
Guaifenesin
an expectorant (not a suppressant) that helps thin mucus; available OTC (Mucinex)
Honey-based remedies
evidence supports honey as effective for nighttime cough in children over 1 year
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CNS depressants
moderate(alcohol, benzodiazepines, opioids, sleep aids) — may increase drowsiness and sedation when combined with Benzonatate
Other local anesthetics
moderatetheoretical additive numbing effects; use caution
MAO inhibitors
moderatepotential for increased side effects; consult your doctor
Medfinder Editorial Standards
Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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