Why Is Besifloxacin So Hard to Find? [Explained for 2026]

Updated:

March 28, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Besifloxacin (Besivance) can be hard to find at pharmacies. Learn why this eye drop is difficult to locate and what you can do to get your prescription filled.

If You're Struggling to Find Besifloxacin, You're Not Alone

You've got a prescription for Besifloxacin eye drops — sold under the brand name Besivance — and your pharmacy says they don't have it. Now you're calling around, feeling frustrated, and wondering why such a basic eye infection medication is so difficult to track down.

The truth is, Besifloxacin availability has been a growing problem in 2026. Whether you're dealing with shortage-related issues or simply can't find a pharmacy that stocks it, there are real reasons behind the difficulty — and real solutions you can try today.

What Is Besifloxacin?

Besifloxacin is a fourth-generation fluoroquinolone antibiotic available as an ophthalmic suspension (eye drops) at a concentration of 0.6%. It's sold exclusively under the brand name Besivance, manufactured by Bausch + Lomb.

Doctors prescribe Besifloxacin to treat bacterial conjunctivitis — commonly known as pinkeye. It works by targeting two key enzymes in bacteria (DNA gyrase and topoisomerase IV), which stops bacteria from replicating and effectively kills the infection.

The typical treatment involves placing one drop in the affected eye three times daily for seven days. It's FDA-approved for patients aged one year and older. For more details about how this medication works, check out our guide on Besifloxacin's mechanism of action.

Why Is Besifloxacin So Hard to Find?

There are several reasons you might be having trouble finding Besifloxacin at your local pharmacy. Here are the most common factors:

1. It's a Brand-Name-Only Medication

As of 2026, there is no generic version of Besifloxacin. The only product on the market is Besivance, made by Bausch + Lomb. When a drug has only one manufacturer and no generic competition, any disruption in production or distribution can cause widespread availability problems.

Generic versions of other fluoroquinolone eye drops — like Moxifloxacin (Vigamox) or Ciprofloxacin (Ciloxan) — are widely available, which makes them easier for pharmacies to stock. Besifloxacin doesn't have that advantage.

2. Limited Pharmacy Stocking

Because Besivance is a brand-name specialty eye drop with a cash price of $130 to $300 per bottle, many pharmacies — especially large chains — may not keep it regularly in stock. They often order it only when a specific prescription comes in, which can create delays of one to three business days.

Independent pharmacies and specialty eye care pharmacies may be more likely to carry it, but availability varies significantly by region.

3. Insurance and Prior Authorization Hurdles

Many insurance plans require prior authorization or step therapy before covering Besivance. Step therapy means your insurer may require you to try a cheaper, generic fluoroquinolone first — such as generic Moxifloxacin or Ciprofloxacin eye drops — before they'll approve Besifloxacin.

This doesn't just affect cost; it can also affect whether your pharmacy bothers to order it. If insurers frequently reject Besivance claims, pharmacies may reduce how much they stock.

4. Single-Manufacturer Supply Chain

With Bausch + Lomb as the sole manufacturer, any production issue — whether it's raw material sourcing, manufacturing delays, or distribution bottlenecks — can ripple across the entire supply chain. While Besifloxacin is not currently on the FDA's official drug shortage list, intermittent supply disruptions have been reported in some regions.

What You Can Do to Find Besifloxacin

If you're struggling to locate Besifloxacin, here are some practical steps:

Use Medfinder to Check Real-Time Availability

Medfinder helps you search for pharmacies near you that have Besifloxacin in stock right now. Instead of calling pharmacy after pharmacy, you can check availability online and save yourself hours of frustration.

Try Independent and Specialty Pharmacies

Large chain pharmacies may not stock Besivance routinely, but independent pharmacies and eye care specialty pharmacies often have better access to ophthalmic medications. Ask your eye doctor's office for recommendations — they often know which local pharmacies carry it.

Ask Your Doctor About Alternatives

If you genuinely can't find Besifloxacin, your doctor may be able to prescribe an alternative fluoroquinolone eye drop like Moxifloxacin (Vigamox), Ofloxacin (Ocuflox), or Ciprofloxacin (Ciloxan). These are available as generics and are much easier to find.

Look Into the Bausch + Lomb Access Program

If cost is a barrier, the Bausch + Lomb Access Program may help. Commercially insured patients may pay as little as $25 per prescription, and cash-paying patients may pay no more than $69. Learn more in our guide on how to save money on Besifloxacin.

Final Thoughts

Finding Besifloxacin in 2026 can feel like a scavenger hunt, but understanding why it's hard to find puts you in a better position to solve the problem. The combination of brand-name exclusivity, limited pharmacy stocking, insurance hurdles, and a single-manufacturer supply chain all contribute to the difficulty.

Your best bets are using a tool like Medfinder to locate pharmacies with stock, trying independent pharmacies, exploring savings programs, and — if needed — discussing alternative medications with your doctor.

Don't let a supply issue delay treatment for your eye infection. Bacterial conjunctivitis needs prompt treatment to prevent complications and reduce the spread of infection.

Is there a generic version of Besifloxacin (Besivance)?

No. As of 2026, there is no FDA-approved generic version of Besifloxacin. Besivance, made by Bausch + Lomb, is the only product available. This contributes to its limited availability and higher cost compared to generic fluoroquinolone eye drops.

Why doesn't my pharmacy carry Besifloxacin?

Many pharmacies don't routinely stock Besivance because it's a brand-name-only product with a high cash price ($130 to $300 per bottle). Pharmacies often order it only when a specific prescription comes in, which can take one to three business days. Independent and specialty pharmacies are more likely to have it available.

Can I use a different eye drop instead of Besifloxacin?

Yes — with your doctor's approval. Other fluoroquinolone eye drops like Moxifloxacin (Vigamox), Ofloxacin (Ocuflox), and Ciprofloxacin (Ciloxan) are commonly prescribed for bacterial conjunctivitis and are available as generics at a much lower cost. Talk to your prescriber about whether a switch is appropriate for you.

Is Besifloxacin on the FDA drug shortage list?

Besifloxacin is not currently listed on the FDA's official drug shortage list. However, because it's made by a single manufacturer with no generic competition, intermittent supply disruptions can occur. Availability varies by pharmacy and region, so checking real-time stock through tools like Medfinder can help.

Why waste time calling, coordinating, and hunting?

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