

Get the latest Medrol (Methylprednisolone) shortage update for 2026. Learn what's causing supply issues and what patients can do to get their prescriptions filled.
If you've been having trouble finding Medrol (Methylprednisolone) at your pharmacy, you're not imagining it. Supply disruptions affecting Methylprednisolone have left many patients scrambling to fill their prescriptions in 2026. This article provides the latest information on the Medrol shortage and what you can do about it.
As of early 2026, Methylprednisolone — sold under the brand name Medrol — has been experiencing intermittent supply disruptions across the United States. The Medrol Dosepak (the popular 21-tablet tapered dose pack) has been particularly affected, though individual-strength tablets have also seen sporadic shortages in some regions.
The situation varies by location. Some pharmacies have adequate stock while others are completely out. This uneven distribution is typical of drug shortages and is often caused by distributor allocation limits.
Several factors are contributing to the current Medrol supply issues:
A small number of companies manufacture generic Methylprednisolone tablets and dose packs. When one or more of these manufacturers experiences production delays — whether from equipment problems, raw material shortages, or regulatory compliance issues — the entire market feels the impact.
Respiratory illness seasons drive significant increases in Methylprednisolone prescriptions. Medrol Dosepaks are commonly prescribed for bronchitis, sinusitis, asthma flare-ups, and severe allergic reactions — all conditions that spike during certain times of year.
The active pharmaceutical ingredient (API) for Methylprednisolone is sourced from a limited number of global suppliers. Disruptions at the API level can affect every manufacturer simultaneously, creating widespread shortages.
When supply is limited, pharmaceutical distributors put pharmacies on "allocation," limiting how much each pharmacy can order. This prevents any single pharmacy from hoarding stock but also means many pharmacies receive less than they need.
Drug shortages are difficult to predict. Some resolve within weeks as manufacturers catch up with demand. Others can persist for months or longer, especially when the root cause involves manufacturing facility issues or raw material supply problems.
We'll continue to update this article as new information becomes available. Bookmark this page and check back for the latest status.
Use MedFinder to search for pharmacies near you that have Medrol or generic Methylprednisolone in stock. This is the fastest way to check multiple pharmacies at once without making dozens of phone calls.
Don't give up after checking one or two pharmacies. Due to allocation limits, availability can vary significantly from one pharmacy to the next — even within the same neighborhood. Independent pharmacies may have different supply sources than major chains. Read our full guide on how to find Medrol in stock near you.
If brand-name Medrol isn't available, generic Methylprednisolone is the same medication. Ask your pharmacist whether generic tablets are in stock.
If you can't find Methylprednisolone in any form, contact your doctor. They can prescribe an alternative corticosteroid such as Prednisone, Prednisolone, or Dexamethasone. Learn more in our guide to Medrol alternatives.
If you've been taking Medrol for more than a few days, stopping suddenly can cause adrenal insufficiency. This is a serious condition that requires medical attention. Always work with your doctor if you need to stop or switch your corticosteroid.
The Medrol Dosepak — a pre-packaged 21-tablet tapered course of Methylprednisolone 4 mg — is one of the most commonly prescribed forms of this medication. Because it's used for acute conditions (like severe allergic reactions or inflammation flare-ups), demand can spike unpredictably.
If the Dosepak isn't available, your doctor can prescribe individual Methylprednisolone tablets with taper instructions. The medication is the same — only the packaging is different.
The Medrol shortage in 2026 is a real challenge for patients who depend on Methylprednisolone. While the supply situation is improving in some areas, it remains inconsistent. Use MedFinder to find pharmacies with stock, talk to your doctor about alternatives if needed, and never stop taking corticosteroids abruptly. We'll continue updating this page as the situation evolves.
You focus on staying healthy. We'll handle the rest.
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