Myfembree costs up to $1,700/month without insurance. Learn how to save with copay cards, discount coupons, patient assistance programs, and more in 2026.
Myfembree (Relugolix/Estradiol/Norethindrone Acetate) is an effective once-daily treatment for heavy menstrual bleeding from uterine fibroids and moderate to severe endometriosis pain. But it comes with a hefty price tag — up to $1,700 per month without insurance.
If you're struggling with the cost of Myfembree, you're not alone. The good news is there are several ways to significantly reduce what you pay. In this guide, we'll cover every major savings option available in 2026, from manufacturer copay programs to discount cards and patient assistance.
Here's what you can expect to pay for a 28-day supply of Myfembree without any insurance or discount programs:
At these prices, a year of Myfembree treatment could cost $14,000 to $20,000 out of pocket — a significant financial burden. That's why it's critical to explore every available savings option.
The most impactful savings option for commercially insured patients is the Myfembree Copay Assistance Program offered by Myovant Sciences (the manufacturer). Here's how it works:
Who qualifies: Patients with commercial health insurance. This program is not available for patients on government insurance (Medicare, Medicaid, Tricare, VA).
If you have commercial insurance, this should be your first step. It can turn a $200+ copay into $0.
If you don't have insurance or your copay is still high after insurance, prescription discount cards can provide meaningful savings — especially on the generic version.
GoodRx shows prices starting at approximately $1,207 for a 28-day supply of generic Myfembree. Prices vary by pharmacy, so compare multiple locations on the GoodRx website or app. The coupon is free to use and accepted at most major pharmacies.
SingleCare offers generic Myfembree for approximately $1,151 for a 28-day supply. Like GoodRx, prices vary by pharmacy. You can print or download the coupon from singlecare.com and present it at the pharmacy counter.
Additional discount programs to check include:
Important note: Discount cards and coupons cannot be combined with insurance copays or government insurance. They're most useful for uninsured patients or those paying cash.
If you're uninsured, underinsured, or experiencing financial hardship, patient assistance programs can provide Myfembree at little or no cost.
Myovant Sciences (the manufacturer) offers a patient assistance program for eligible patients who cannot afford their medication. Eligibility is typically based on income and insurance status. Contact Myovant's patient support team through myfembree.com/cost-and-support for details and application information.
NeedyMeds is a nonprofit that maintains a database of patient assistance programs, including those for Myfembree. They can help you find manufacturer programs, state-based assistance, and other resources.
RxAssist is another resource that connects patients with pharmaceutical company assistance programs. Search for Myfembree on their website to find current program details.
If your doctor approves, switching from brand-name Myfembree to the generic (Relugolix/Estradiol/Norethindrone Acetate) can save you $300 to $500 per month, depending on the pharmacy and discount program used. The generic contains the same active ingredients in the same doses (40 mg / 1 mg / 0.5 mg).
Some insurance plans place Myfembree on a preferred tier, which means lower copays. Others may require prior authorization or step therapy. If Myfembree is on a non-preferred tier, ask your doctor to submit an appeal or request a formulary exception. Your doctor can write a letter of medical necessity explaining why Myfembree is the best option for your condition.
If you're on Medicare Part D, the 2025 out-of-pocket spending cap of $2,000 per year applies to all covered medications, including Myfembree. This means your total annual drug costs are capped, which can significantly reduce your monthly burden once you hit the cap — especially for a medication this expensive.
Some states offer their own pharmaceutical assistance programs that can help cover the cost of expensive medications. Contact your state's health department or visit NeedyMeds for a list of programs available in your state.
Myfembree pricing varies significantly from pharmacy to pharmacy. Use Medfinder to find pharmacies that have it in stock, then compare prices using GoodRx or SingleCare to find the best deal in your area.
Myfembree is an expensive medication, but no one should have to go without effective treatment for uterine fibroids or endometriosis because of cost. Between the manufacturer's copay assistance program, prescription discount cards, patient assistance programs, and the availability of a generic version, there are real options to make Myfembree more affordable in 2026.
Start by checking whether you qualify for the copay assistance program, then explore discount cards for the generic version. And if you're having trouble finding Myfembree at your pharmacy, visit Medfinder to check real-time availability near you.
For more information about finding Myfembree, see our guides on how to find Myfembree in stock and why Myfembree is so hard to find.
You focus on staying healthy. We'll handle the rest.
Try Medfinder Concierge FreeMedfinder's mission is to ensure every patient gets access to the medications they need. We believe this begins with trustworthy information. Our core values guide everything we do, including the standards that shape the accuracy, transparency, and quality of our content. We’re committed to delivering information that’s evidence-based, regularly updated, and easy to understand. For more details on our editorial process, see here.
%2C%20Color%3DOriginal.png)
