Envarsus XR can cost over $1,000/month without help. Learn how to save with coupons, discount cards, manufacturer programs, and patient assistance in 2026.
If you've seen the cash price for Envarsus XR, you probably felt your stomach drop. This transplant medication can cost $271 to over $1,500 per month depending on your dose, and there's no generic version to fall back on.
For kidney transplant patients who need Envarsus XR every single day for the rest of their lives, that cost adds up fast. But there are real ways to reduce what you pay — from discount cards to manufacturer programs to patient assistance. Let's break them all down.
Without any insurance or discounts, here's what you can expect to pay for a 30-day supply of Envarsus XR in 2026:
These prices vary by pharmacy and region. Patients on higher doses (who may take multiple tablets daily) face even steeper costs.
For context, generic immediate-release Tacrolimus capsules (the Prograf equivalent) cost only $15 to $50 per month — but they are not interchangeable with Envarsus XR. You cannot simply switch to save money without your transplant doctor's involvement and close monitoring.
Prescription discount cards can significantly reduce the cash price of Envarsus XR. These are free to use and work even without insurance:
SingleCare currently offers Envarsus XR for approximately $211 per month — a savings of about $60 off the average cash price. SingleCare coupons are accepted at most major pharmacies including CVS, Walgreens, Walmart, and Kroger.
Several other discount card services may offer competitive pricing:
Important tip: Prices vary by pharmacy, so always compare across multiple locations. The same discount card may offer a significantly different price at CVS vs. Walmart vs. an independent pharmacy.
Note: Discount cards generally cannot be combined with insurance. Have your pharmacist compare the discount card price to your insurance copay and use whichever is lower.
Veloxis Pharmaceuticals, the maker of Envarsus XR, offers several programs to help patients afford their medication:
For commercially insured patients, Veloxis offers a copay assistance program that can reduce your out-of-pocket costs. Eligibility requirements apply, and the program is not available for patients with government insurance (Medicare, Medicaid, Tricare).
Veloxis has offered a free trial program for eligible new patients starting Envarsus XR. Check with your transplant team or call Veloxis directly to see if this program is currently active.
For uninsured or underinsured patients who meet income eligibility criteria, Veloxis offers a patient assistance program that may provide Envarsus XR at no cost. Contact Veloxis at 1-844-VELOXIS (1-844-835-6947), Monday through Friday, 9 AM to 7 PM ET, to learn about eligibility and enrollment.
Beyond the manufacturer's own programs, several nonprofit organizations help transplant patients afford their medications:
NeedyMeds maintains a database of patient assistance programs, discount cards, and other resources for expensive medications including Envarsus XR. Their website is free to use.
RxAssist is a comprehensive database of patient assistance programs run by pharmaceutical manufacturers. Search for Tacrolimus or Envarsus XR to find current programs.
RxHope helps patients connect with manufacturer assistance programs and other resources for unaffordable medications.
The American Kidney Fund offers financial assistance to kidney transplant patients, including help with medication costs. Their Health Insurance Premium Program and other initiatives may help cover immunosuppressant expenses.
Most insurance plans cover Envarsus XR, but the details matter:
Medicare typically covers Envarsus XR through Part B (as a medical benefit related to transplant surgery) or Part D (prescription drug coverage). If your transplant was performed at a Medicare-certified facility, immunosuppressant coverage generally continues for the life of the transplant.
Medicare copays for specialty-tier medications can still be significant. The Medicare Extra Help program (Low-Income Subsidy) can reduce Part D costs for qualifying patients.
Most commercial plans cover Envarsus XR but may require:
If your plan denies coverage, ask your transplant team to file an appeal. Medical necessity appeals for immunosuppressant medications in transplant patients are often successful.
Envarsus XR tablets should not be split or crushed — they are extended-release formulations. Do not attempt to split tablets to save money. This can alter the drug release profile and put your transplant at risk.
The same medication can vary in price by hundreds of dollars between pharmacies. Use tools like Medfinder and GoodRx to compare prices at pharmacies in your area. Independent pharmacies sometimes offer better pricing than chains for specialty medications.
If Envarsus XR is unaffordable, don't just stop taking it — talk to your transplant nephrologist. They can:
For more on Envarsus XR availability, see our guide on how to find Envarsus XR in stock near you. For the latest supply update, read our 2026 shortage update.
Envarsus XR is an expensive medication with no generic alternative, but you're not stuck paying full price. Between manufacturer savings programs, discount cards like SingleCare (around $211/month), nonprofit patient assistance programs, and insurance optimization, most patients can find a way to make it affordable.
The most important thing: never skip doses because of cost. If you're struggling to afford Envarsus XR, reach out to your transplant team, call Veloxis at 1-844-835-6947, or search Medfinder for the best prices near you. Your transplanted kidney is worth the effort.
You focus on staying healthy. We'll handle the rest.
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