Creon can cost $700–$1,500/month without insurance. Learn how to save with coupons, discount cards, AbbVie's savings programs, and more in 2026.
If you've ever picked up Creon (Pancrelipase) without insurance or with a high-deductible plan, you know the sticker shock. A single month's supply of Creon can cost $700 to $1,500 or more out of pocket, depending on your prescribed strength and dose. For a medication you need to take with every meal and snack just to digest food, those numbers add up fast.
The good news is that there are real ways to reduce what you pay for Creon in 2026. This guide covers manufacturer savings programs, discount cards, patient assistance programs, and other strategies that can bring your costs down significantly — sometimes to $0.
Creon is one of the more expensive medications many patients encounter. Here's a breakdown of typical cash prices by strength:
These prices vary by pharmacy. Some pharmacies charge significantly more than others for the exact same medication, which is why it pays to shop around.
There is no generic version of Creon, so you can't save money by switching to a generic. However, there are several other ways to lower your costs.
AbbVie, the manufacturer of Creon, offers a Creon Savings Card that can significantly reduce your copay. Here's how it works:
Important: The Creon Savings Card is not valid for patients with government insurance, including Medicare, Medicaid, Tricare, or VA benefits. If you have government insurance, see the Patient Assistance section below.
If you don't have insurance or your insurance doesn't cover Creon well, prescription discount cards can help reduce the cash price. These cards are free to use and accepted at most pharmacies:
Prices vary significantly between pharmacies even with discount cards, so always compare. Some independent pharmacies may offer lower prices than chains for specialty medications like Creon.
Tip: Discount cards cannot be combined with insurance. You'll use either your insurance or the discount card — whichever gives you the better price.
If you're uninsured or underinsured and can't afford Creon, the AbbVie Patient Assistance Foundation (PAF) may provide Creon at no cost. Here are the details:
This program is available to patients with government insurance (Medicare, Medicaid) as well as uninsured patients, though specific eligibility criteria may vary. The application process typically takes 1–2 weeks.
While there's no generic Creon, other branded PERT products may have different pricing or better insurance coverage on your specific plan. Ask your doctor about Zenpep, Pancreaze, or Pertzye as potential alternatives. For a full comparison, see our guide on alternatives to Creon.
Many insurance plans offer lower copays for 90-day mail-order supplies compared to 30-day retail fills. If you're on a stable Creon dose, switching to mail-order can save you money and reduce the hassle of monthly pharmacy visits. Check with your insurance plan for mail-order options.
Creon prices can vary by $200 or more between pharmacies in the same area. Use Medfinder to find pharmacies with stock, then compare prices using GoodRx or SingleCare before filling your prescription. Don't assume your usual pharmacy has the best price.
Some states offer their own pharmaceutical assistance programs for residents who need help paying for medications. These programs vary by state but can provide significant savings on high-cost medications like Creon. Contact your state's health department or visit Medicare.gov to find programs in your area.
Your doctor's office may have Creon samples from AbbVie representatives. While this isn't a long-term solution, samples can bridge a gap while you're waiting for insurance approval, assistance program enrollment, or a refill.
Creon is expensive, but you don't have to pay full price. Between AbbVie's savings card, the Patient Assistance Foundation, discount cards, and smart pharmacy shopping, most patients can find a way to make Creon more affordable.
Start by checking if you qualify for AbbVie's programs — they offer the biggest savings. If those don't apply to you, compare prices using discount cards and consider switching to mail-order pharmacy for additional savings.
And if cost is making it hard to stay on your medication, don't suffer in silence. Talk to your doctor about your options. There are also alternative PERT products that may be more affordable on your specific insurance plan. Use Medfinder to find pharmacies with Creon in stock, and check out our other guides:
You focus on staying healthy. We'll handle the rest.
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