Compro Can Be Expensive — But You Don't Have to Pay Full Price

Compro (Prochlorperazine 25 mg suppositories) is a vital medication for managing severe nausea and vomiting, especially when you can't keep oral medications down. But when you go to fill your prescription, the price can come as a shock — particularly without insurance.

The retail price for Compro brand suppositories runs $80 to $175 for just 12 suppositories. Even generic prochlorperazine suppositories can cost $50 to $80 at full retail price. That's a lot for a medication you may need regularly.

The good news? There are concrete ways to bring that cost down significantly — from free coupon cards to patient assistance programs. This guide covers every major savings strategy available in 2026.

What Does Compro Cost Without Insurance?

Let's start with the baseline so you know what you're working with:

• Compro brand (12 suppositories, 25 mg): $80 to $175
• Generic prochlorperazine suppositories (12 ct, 25 mg): $50 to $80 retail
• Generic prochlorperazine oral tablets (30 ct, 10 mg): $15 to $50 retail
• Generic prochlorperazine oral tablets (30 ct, 5 mg): $15 to $45 retail

These prices vary by pharmacy and region. The suppository form is consistently more expensive than oral tablets because of higher manufacturing costs and lower production volume.

Coupon and Discount Cards: Your Easiest Savings

The simplest way to save on Compro or generic prochlorperazine is to use a free prescription coupon card. These cards are accepted at most major pharmacies and can cut the price dramatically:

Best Coupon Cards for Prochlorperazine

• GoodRx — Prochlorperazine oral tablets as low as $3.36 for 30 tablets (10 mg). Suppositories starting around $27 to $35 for 12 count with a coupon.
• SingleCare — Prochlorperazine maleate tablets around $9 to $15 for 30 tablets. Compro suppositories around $34.81 for 12 count.
• RxSaver — Compare prices at nearby pharmacies with coupons. Often finds competitive pricing at Costco, Walmart, and independent pharmacies.
• Optum Perks — Free coupons that can reduce the cost of generic prochlorperazine by up to 80%.
• BuzzRx — Accepted at over 60,000 pharmacies, with savings on both tablet and suppository forms.

How Coupon Cards Work

These cards are free — no sign-up fees, no insurance required, no income restrictions. Here's how to use them:

1. Visit the coupon card website (e.g., goodrx.com, singlecare.com) or download their app
2. Search for "prochlorperazine" or "Compro"
3. Compare prices at pharmacies near you
4. Show the coupon (on your phone or printed) to the pharmacist when filling your prescription

Important: Coupon card prices are cash prices — they're used instead of insurance, not in addition to it. If your insurance copay is lower than the coupon price, use your insurance. If the coupon price is lower, use the coupon. You can ask your pharmacist to run both and tell you which is cheaper.

Where to Fill for the Lowest Price

Coupon card prices vary by pharmacy. Here are some consistently low-cost options:

• Costco — often has the lowest generic prices (you don't need a Costco membership to use the pharmacy)
• Walmart — competitive generic pricing; prochlorperazine tablets may be on their low-cost generic list
• Kroger / Fry's — good coupon prices for generic prochlorperazine
• Independent pharmacies — prices vary but some offer very competitive cash pricing, especially for generics

Patient Assistance Programs

Because prochlorperazine is available only as a generic (the brand names Compazine and Compro have been discontinued as active brands with manufacturer support), there is no active manufacturer savings or copay card program. However, several third-party patient assistance resources can help:

NeedyMeds (needymeds.org)

NeedyMeds maintains a comprehensive database of patient assistance programs, discount coupons, and free/low-cost clinic locations. Search for "prochlorperazine" to find applicable programs in your area.

RxAssist (rxassist.org)

RxAssist provides a directory of patient assistance programs offered by pharmaceutical companies, government agencies, and non-profit organizations. While there's no manufacturer program specific to prochlorperazine, RxAssist can help you find general medication assistance programs you may qualify for.

State Pharmaceutical Assistance Programs (SPAPs)

Many states operate pharmaceutical assistance programs for low-income residents, seniors, or people with disabilities. These programs can help cover the cost of prochlorperazine. Check with your state's health department or visit Medicare.gov for a list of SPAPs.

Manufacturer Patient Assistance (Padagis)

Padagis US LLC, the manufacturer of Compro, does not currently operate a public patient assistance program for this product. However, it's worth contacting them directly at their website (padagis.com) if you're experiencing financial hardship, as policies can change.

Other Ways to Save on Compro

Ask About Oral Tablets Instead

If you can tolerate oral medications, prochlorperazine 5 mg or 10 mg tablets are dramatically cheaper than suppositories — as low as $3 to $16 for 30 tablets with a coupon. That's potentially less than one-tenth the cost of suppositories. Talk to your doctor about whether oral prochlorperazine could work for your situation.

Request a 90-Day Supply

If you use prochlorperazine regularly, a 90-day prescription can reduce your per-unit cost. Many pharmacies and insurance plans offer discounts on larger quantities. Mail-order pharmacy services (available through many insurance plans) often provide 90-day supplies at a lower overall cost.

Compare Pharmacy Prices Every Time

Pharmacy prices for the same generic medication can vary by $50 or more depending on where you fill. Don't assume your regular pharmacy has the best price. Use GoodRx, SingleCare, or Medfinder to compare prices before each fill — pricing can change month to month.

Consider a Prescription Savings Membership

Programs like GoodRx Gold ($9.99/month) or RxSaver Plus offer even deeper discounts beyond the free coupon cards. If you fill prochlorperazine regularly, the monthly fee can easily pay for itself. GoodRx Gold prices for prochlorperazine start as low as $8.12.

Check If Your Insurance Covers It

If you have insurance, prochlorperazine is typically covered as a Tier 1 preferred generic on most commercial, Medicaid, and Medicare Part D formularies. Copays are usually $0 to $15. Prior authorization is generally not required. If your insurance isn't covering it or the copay seems high, ask your pharmacist to check — sometimes there's a formulary issue that can be resolved with a quick call to the insurer.

Savings Summary: What You Could Pay

Here's what your actual out-of-pocket cost could look like with these strategies:

• Prochlorperazine 10 mg tablets (30 ct) with GoodRx: as low as $3.36
• Prochlorperazine 10 mg tablets (30 ct) with SingleCare: around $9 to $15
• Generic prochlorperazine suppositories (12 ct) with coupon: $27 to $35
• Compro brand suppositories (12 ct) with coupon: $35 to $80
• With insurance (generic tablets): $0 to $15 copay

Compare that to the full retail price of $80 to $175, and the savings are substantial.

Final Thoughts

You shouldn't have to choose between managing severe nausea and paying your other bills. Prochlorperazine is an effective, well-established medication, and with the right savings strategy, it doesn't have to break the bank.

Start by comparing prices on GoodRx or SingleCare, ask your pharmacist to check whether your insurance copay or the coupon price is lower, and consider oral tablets if the suppository cost is prohibitive. If you're struggling financially, reach out to NeedyMeds or RxAssist for additional assistance options.

For help finding Compro in stock at a pharmacy near you, use Medfinder. And for a complete overview of the medication, visit What Is Compro? Uses, Dosage, and What You Need to Know. To learn about alternative medications that may be more affordable, see Alternatives to Compro.