Learn how to find a doctor who can prescribe Orilissa for endometriosis pain. Tips on finding OB/GYNs, specialists, and what to expect at your appointment.
If you've been dealing with moderate to severe endometriosis pain, you may have heard about Orilissa (Elagolix) — the first oral GnRH antagonist approved specifically for endometriosis. But getting a prescription starts with finding the right doctor. Not every provider is familiar with this medication, and knowing where to look can save you weeks of frustration.
This guide walks you through how to find a doctor who can prescribe Orilissa, what to expect at your appointment, and how to make the process as smooth as possible.
Orilissa is primarily prescribed by OB/GYNs (obstetrician-gynecologists) who treat endometriosis. However, other specialists may also prescribe it:
Your primary care doctor can refer you to one of these specialists. In some cases, a PCP who is knowledgeable about endometriosis may initiate the prescription themselves, though this is less common since Orilissa requires specific monitoring (like liver function tests and bone density considerations).
Start with your insurance company's provider directory. Log in to your insurance website or call the number on the back of your card. Search for OB/GYN or reproductive endocrinology specialists in your area. This ensures the doctor you see is in-network, which can significantly reduce your out-of-pocket costs.
When calling to schedule, ask: "Does the doctor have experience prescribing Orilissa or other GnRH antagonists for endometriosis?"
Online directories like Zocdoc, Healthgrades, and Vitals let you filter doctors by specialty, insurance accepted, and patient reviews. Search for "OB/GYN" or "endometriosis specialist" in your zip code. Patient reviews can give you a sense of whether a provider is open to discussing newer treatment options like Orilissa.
If you already have a primary care doctor or gynecologist, ask them directly for a referral to someone who prescribes Orilissa. Doctors who treat endometriosis regularly often know which colleagues in the area are comfortable with GnRH antagonist therapy.
You can also ask at local endometriosis support groups or online communities (like the endometriosis subreddit or Endo Foundation forums) for doctor recommendations in your area.
Academic medical centers and women's health clinics affiliated with hospitals often have endometriosis programs. These clinics tend to be more familiar with Orilissa and can coordinate the monitoring it requires. Look for "Center for Endometriosis" or "Pelvic Pain Clinic" in your area.
AbbVie, the manufacturer of Orilissa, offers patient support through their website at orilissa.com. While they don't provide a doctor directory, their support team (1-800-222-6885) may be able to help connect you with prescribers in your region.
Once you've found a doctor, here's what to prepare for:
Your doctor will likely:
Getting the prescription is just the first step. Here are a few things to keep in mind:
Orilissa is a specialty medication that costs $1,200 to $1,700 per month without insurance. Many retail pharmacies don't keep it on their shelves. You may need to use a specialty pharmacy, which your doctor's office can help arrange.
You can also use Medfinder to check which pharmacies near you have Orilissa in stock without having to call around.
Most commercial insurance plans cover Orilissa but often require prior authorization and sometimes step therapy (trying other treatments first). Your doctor's office will typically handle the prior auth process.
If cost is a concern, check out our guide on how to save money on Orilissa. AbbVie's savings card can reduce your copay to as little as $5 per month for commercially insured patients.
Your doctor will want to see you regularly while you're on Orilissa — typically every few months. They'll monitor your symptoms, check liver function, and assess whether any side effects need to be addressed. Don't skip these appointments.
Finding a doctor who can prescribe Orilissa doesn't have to be overwhelming. Start with your insurance directory, look for OB/GYNs or reproductive endocrinologists who treat endometriosis, and come to your appointment prepared. The right provider will work with you to determine if Orilissa is the best option for managing your endometriosis pain.
Ready to find Orilissa near you? Search Medfinder to check pharmacy availability in your area.
You focus on staying healthy. We'll handle the rest.
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