Eylea in 2026: What's the Latest?

If you depend on Eylea (Aflibercept) injections to manage your eye condition, you've probably noticed that getting your treatment on time hasn't been easy lately. Supply constraints, rising costs, and scheduling headaches have been frustrating patients and providers alike.

In this 2026 update, we'll cover everything you need to know: whether Eylea is still in shortage, what's driving the supply issues, how much it costs now, what new options are available, and how to find Eylea in stock near you.

Is Eylea Still in Shortage in 2026?

The short answer: it depends on where you are. Eylea hasn't been placed on the FDA's official drug shortage list as a critical shortage, but many retina practices across the country have reported intermittent difficulty obtaining consistent supply since 2023.

Some regions and practices have steady access, while others — particularly smaller practices and those in rural areas — may experience gaps between shipments. The situation has improved compared to the worst periods in 2023 and 2024, but it's not fully resolved.

Regeneron Pharmaceuticals, the manufacturer of Eylea, has been working to increase production capacity. Additionally, the anticipated arrival of Aflibercept biosimilars in the coming months could help ease supply pressure significantly.

Why Is Eylea Hard to Find?

Several factors contribute to the ongoing supply challenges:

• Biologic manufacturing complexity — Eylea is produced from living cells, requiring specialized facilities and strict quality controls. Production cannot be scaled quickly.
• Massive global demand — Millions of patients worldwide rely on regular Eylea injections, creating consistent high-volume demand.
• No biosimilars yet — Unlike some other biologic drugs, affordable biosimilar alternatives to Aflibercept are not yet widely available in the U.S.
• Distribution allocation — When supply is limited, manufacturers allocate based on historical ordering, which can disadvantage smaller or newer practices.

For a more detailed breakdown, read our article on why Eylea is so hard to find.

How Much Does Eylea Cost in 2026?

Eylea remains one of the more expensive medications on the market:

• Standard Eylea (2 mg): Approximately $1,800 to $2,200 per injection
• Eylea HD (8 mg): Approximately $1,100 to $1,200 per injection

Most patients don't pay the full cash price. Here's how costs typically break down:

• Medicare Part B: Covers Eylea as a physician-administered drug. Patients typically pay 20% coinsurance, which comes to roughly $360 to $440 per injection before any supplemental coverage kicks in.
• Commercial insurance: Most plans cover Eylea with prior authorization. Copays vary widely — from $0 with copay assistance to several hundred dollars per injection.
• Uninsured patients: May be eligible for Regeneron's patient assistance program, which can provide Eylea at no cost.

For a complete guide to saving money, read our article on how to save money on Eylea in 2026.

New Options for Patients in 2026

The treatment landscape for retinal conditions continues to evolve. Here are the key developments to know about:

Eylea HD (8 mg Aflibercept)

Approved by the FDA in 2023, Eylea HD delivers a higher dose of Aflibercept, which may allow patients to go 12 to 16 weeks between injections instead of the standard 4 to 8 weeks. This means fewer office visits and potentially fewer supply-related disruptions.

Upcoming Biosimilars

Several companies are developing biosimilar versions of Aflibercept. Once approved and available, these are expected to:

• Increase overall supply of Aflibercept
• Lower costs by 15% to 30% compared to branded Eylea
• Give retina practices more sourcing options

Vabysmo (Faricimab)

Approved in 2022, Vabysmo has quickly become a major alternative to Eylea. It targets both VEGF-A and Ang-2, and clinical trials showed it was as effective as Eylea with potentially longer dosing intervals. If Eylea isn't available, Vabysmo is often the first alternative doctors consider. Learn more in our guide on alternatives to Eylea.

How to Find Eylea in Stock

If you need to locate Eylea for your next injection, here's what to do:

1. Use Medfinder: Visit medfinder.com to check which providers near you currently have Eylea available.
2. Call specialty retina practices: Larger practices and academic medical centers often have more reliable supply.
3. Ask about Eylea HD: Your doctor may have the 8 mg formulation in stock even when the standard 2 mg is unavailable.
4. Schedule ahead: Book your next 2 to 3 appointments in advance so your provider can plan supply accordingly.

For a detailed walkthrough, see our guide on how to find Eylea in stock near you.

Final Thoughts

The Eylea supply situation in 2026 is improving but not yet fully resolved. The arrival of Eylea HD, upcoming biosimilars, and growing alternatives like Vabysmo are all positive signs. In the meantime, stay proactive: keep your appointments, communicate with your retina specialist, and use tools like Medfinder to stay ahead of supply disruptions.

Your vision depends on consistent treatment. Don't let supply issues stop you from getting the care you need.