Ddavp in 2026: Is the Shortage Over?

If you depend on Ddavp (Desmopressin) to manage diabetes insipidus, a bleeding disorder, or bedwetting, you've probably felt the impact of supply disruptions over the past few years. The question on every patient's mind: is the Ddavp shortage over in 2026?

The short answer is: it's complicated. Some formulations are easier to find than others, and availability varies by region and pharmacy. Here's everything you need to know about the current state of Ddavp supply, pricing, and what you can do if you're still having trouble.

Is Ddavp Still in Shortage?

The injectable form of Desmopressin (4 mcg/mL, used in hospitals for bleeding disorders and surgical situations) has been listed on the FDA Drug Shortages database intermittently since mid-2023. As of early 2026, supply remains inconsistent, with some manufacturers reporting limited availability.

Oral tablets (generic Desmopressin 0.1 mg and 0.2 mg) are generally more available, but individual pharmacies may be out of stock due to ordering patterns, local demand, or wholesaler allocation limits. The brand-name DDAVP tablets are harder to find as most prescriptions have shifted to generics.

Nasal spray formulations have more limited supply. The brand-name DDAVP Nasal Spray and Stimate Nasal Spray (the higher-concentration version for bleeding disorders) are produced by fewer manufacturers, making them more vulnerable to shortages.

Sublingual tablets (Nocdurna) for nocturia have their own supply chain and are generally available, though they're expensive without insurance — often $400–$500 per month.

Why Is Ddavp Hard to Find?

Several factors have contributed to the ongoing difficulty in finding Desmopressin:

• Manufacturing disruptions: Production issues at key facilities have reduced output of the injectable form, with ripple effects on other formulations
• Fewer manufacturers: Generic manufacturer consolidation means fewer companies are making Desmopressin products. When even one has a production issue, supply drops significantly.
• Increased demand: The approval of new nocturia indications (Nocdurna, Noctiva) has expanded the patient population using Desmopressin, increasing overall demand
• Wholesaler allocation: When supply is tight, drug wholesalers may limit how much each pharmacy can order, leaving some locations with zero stock while others have some

For more detail, read our full article on why Ddavp is so hard to find.

What Does Ddavp Cost in 2026?

The cost of Desmopressin varies widely depending on the formulation and whether you're buying brand-name or generic:

• Generic Desmopressin oral tablets (0.1 mg or 0.2 mg): $15–$60 for a 30-day supply without insurance
• Brand-name DDAVP tablets: $150–$300+ for a 30-day supply
• DDAVP Nasal Spray: $300–$500 for a bottle (brand-name)
• Generic Desmopressin nasal spray: $80–$200
• Stimate Nasal Spray: $3,000–$5,000+ (high-concentration for bleeding disorders)
• Nocdurna sublingual tablets: $400–$500 per month
• Desmopressin injection: $50–$150 per vial

If you're paying cash, generic Desmopressin tablets are by far the most affordable option. Discount cards from GoodRx, SingleCare, and other providers can help lower costs further. For a complete guide to saving money, read how to save money on Ddavp.

New Options and Developments

A few developments in 2025–2026 are worth noting:

• Additional generic approvals: The FDA has continued to approve generic versions of Desmopressin products, which should gradually improve supply and lower costs
• Telehealth prescribing: More providers are prescribing Desmopressin via telehealth, making it easier for patients to get prescriptions without office visits. Learn more about finding a doctor who prescribes Ddavp.
• Real-time inventory tools: Tools like Medfinder have made it much easier to find pharmacies with Desmopressin in stock, reducing the guesswork

How to Find Ddavp in Stock Right Now

If you need Desmopressin today, here's your action plan:

1. Check Medfinder for real-time pharmacy inventory in your area
2. Call independent pharmacies — they often have more sourcing flexibility than chains
3. Ask your doctor about formulation switches — if the nasal spray is unavailable, tablets might work (and vice versa)
4. Consider mail-order pharmacies — they typically carry larger inventories
5. Look into 90-day supplies — if you find it, filling a 90-day prescription reduces the frequency of refill struggles

For a detailed step-by-step guide, read how to find Ddavp in stock near you.

Final Thoughts

The Ddavp shortage situation in 2026 is improving slowly, but it's not fully resolved — especially for the injectable and nasal spray forms. Generic Desmopressin tablets are the most readily available and affordable option for most patients. If you're struggling to find your medication, use Medfinder to check stock, talk to your doctor about alternatives, and don't hesitate to explore independent pharmacies and mail-order options.

Stay informed by checking back for updates. For more on alternatives, read our guide to Ddavp alternatives. For drug interactions and safety information, see Ddavp drug interactions.