The Anagrelide Shortage: Where Things Stand in 2026

If you take Anagrelide for essential thrombocythemia, you've probably felt the effects of supply disruptions firsthand. Empty shelves, back-ordered prescriptions, and the stress of wondering when — or if — your pharmacy will get more. This article gives you the latest on the Anagrelide shortage in 2026 and what you can do about it.

Is Anagrelide Still in Shortage?

Anagrelide has faced intermittent availability issues for several years. The American Society of Health-System Pharmacists (ASHP) has tracked anagrelide hydrochloride capsule shortages, and the situation has fluctuated over time.

As of early 2026, Teva continues to manufacture and supply generic anagrelide capsules in both 0.5 mg and 1 mg strengths. However, availability at individual pharmacies can still be inconsistent, particularly at large retail chains that may not routinely stock this medication.

The shortage isn't a complete absence of the drug from the market — it's more of a spotty, regional availability problem. Some pharmacies have it, others don't. And if your pharmacy doesn't stock it, getting it ordered can take several days.

Why Is Anagrelide Hard to Find?

Several factors have converged to create ongoing availability challenges:

Fewer Manufacturers

The biggest factor is the shrinking number of generic manufacturers. Mylan Pharmaceuticals discontinued its anagrelide capsules in 2015, leaving fewer companies in the market. With less manufacturing capacity, any production hiccup at a remaining supplier can cause ripple effects across the entire supply chain.

Niche Patient Population

Essential thrombocythemia affects a relatively small number of people compared to conditions like diabetes or high blood pressure. This means Anagrelide is produced in smaller quantities, and pharmacies are less likely to keep it regularly in stock.

Supply Chain Fragility

Pharmaceutical supply chains remain under pressure from raw material sourcing challenges, quality control requirements, and logistics bottlenecks. For a low-volume medication with limited manufacturers, these pressures hit harder.

For a deeper look at these issues, read our full article on why Anagrelide is so hard to find in 2026.

How Much Does Anagrelide Cost in 2026?

Cost can add another layer of difficulty for patients trying to fill their prescriptions. Here's what you can expect:

• Retail price without insurance: Approximately $481 for 60 capsules (0.5 mg) — a typical 30-day supply
• With discount coupons (GoodRx, SingleCare): As low as $48 to $91 for 60 capsules (0.5 mg)
• Brand-name Agrylin: Around $645 for 60 capsules without insurance
• With insurance: Copays vary widely depending on your plan, but generic Anagrelide is typically on formulary for most plans

If cost is a barrier, we've compiled a full guide on how to save money on Anagrelide, including coupons, discount programs, and patient assistance options.

Are There New Options in 2026?

While no new formulations of Anagrelide have been released recently, the treatment landscape for essential thrombocythemia continues to evolve:

• Hydroxyurea remains the most widely used first-line treatment and is readily available at a fraction of the cost
• Pegylated Interferon Alfa-2a (Pegasys) continues to gain traction, especially for younger patients
• Research into JAK inhibitors and other targeted therapies for myeloproliferative neoplasms is ongoing

If you're interested in exploring alternatives, check out our guide on alternatives to Anagrelide.

How to Find Anagrelide in Stock Right Now

Here's your action plan for finding Anagrelide today:

1. Search on Medfinder — check which pharmacies near you have Anagrelide available right now
2. Call independent pharmacies — they often have more flexibility in ordering and sourcing medications
3. Try specialty pharmacies — pharmacies that focus on hematology or oncology are more likely to carry Anagrelide
4. Ask about mail-order options — your insurance plan may offer a mail-order pharmacy with better access to specialty medications
5. Request a 90-day supply — reduces how often you need to refill and gives you a buffer against future shortages

For a detailed walkthrough, see our step-by-step guide on how to find Anagrelide in stock near you.

Final Thoughts

The Anagrelide shortage situation in 2026 isn't a crisis — but it's a persistent headache for patients who need this medication. Teva continues to supply generic anagrelide capsules, but limited manufacturer diversity means availability can be unpredictable.

Stay proactive: refill early, use tools like Medfinder, build a relationship with a pharmacy that reliably stocks your medication, and keep your hematologist informed about any access challenges. If you're a provider looking for clinical guidance, see our provider-focused shortage update.

You deserve consistent access to the medications that keep you healthy. With the right plan, you can navigate the shortage and stay on track with your treatment.