Comprehensive medication guide to Suprep Bowel Prep Kit including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$10–$50 copay; covered by most Medicare Part D and commercial plans, prior authorization typically not required.
Estimated Cash Pricing
$124–$170 for brand-name Suprep; as low as $35–$75 with GoodRx or SingleCare coupons.
Medfinder Findability Score
82/100
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Suprep Bowel Prep Kit is a prescription osmotic laxative used to cleanse the colon before a colonoscopy. It is FDA-approved for adults and pediatric patients 12 years of age and older. The kit contains two bottles of a flavored oral solution concentrate made up of sodium sulfate, potassium sulfate, and magnesium sulfate. Patients drink each dose diluted with water, followed by additional water, as part of a split-dose regimen the evening before and morning of their colonoscopy.
Suprep is manufactured by Braintree Laboratories (a subsidiary of Sebela Pharmaceuticals) and has become one of the most commonly prescribed bowel preps due to its relatively low volume compared to older 4-liter PEG preps like GoLYTELY. A generic version is also available, which can significantly reduce costs.
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Suprep Bowel Prep Kit works through osmotic action. The sulfate salts (sodium sulfate, potassium sulfate, and magnesium sulfate) are poorly absorbed by the intestines. When these salts reach the colon, they draw large amounts of water into the intestinal lumen through osmosis. This dramatically increases the volume and water content of stool, producing watery diarrhea that thoroughly cleanses the colon. A clean colon is essential for your gastroenterologist to get a clear view during colonoscopy and accurately detect polyps, abnormal tissue, or other findings.
Adult kit
Two 6-ounce bottles of oral solution concentrate (each containing 17.5g sodium sulfate, 3.13g potassium sulfate, 1.6g magnesium sulfate), plus a mixing container
Pediatric kit (ages 12+)
Two 4.5-ounce bottles of oral solution concentrate (each containing 13.13g sodium sulfate, 2.35g potassium sulfate, 1.2g magnesium sulfate), plus a mixing container
Suprep Bowel Prep Kit scores an 82 out of 100 on our findability scale, meaning it is generally available at most pharmacies. It is not currently listed on the FDA Drug Shortage Database, and both brand-name Suprep and generic versions (sodium sulfate, potassium sulfate, and magnesium sulfate oral solution) are widely stocked. Occasional localized availability issues may occur at individual pharmacies due to supply chain variability, especially during periods of high colonoscopy screening demand. If your local pharmacy is out of stock, try calling nearby locations or using Medfinder to locate pharmacies with it in stock.
Suprep Bowel Prep Kit is most commonly prescribed by:
In most cases, you'll receive a Suprep prescription directly from the office scheduling your colonoscopy, along with detailed prep instructions.
No, Suprep Bowel Prep Kit is not a controlled substance. It has no potential for abuse or dependence and is not scheduled by the DEA. However, it is a prescription medication and cannot be purchased over the counter — you will need a prescription from your doctor.
Most side effects of Suprep are related to the bowel-cleansing process itself and are temporary:
Serious side effects (seek medical attention immediately):
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GoLYTELY (PEG-3350 with electrolytes)
A large-volume (4-liter) PEG-based bowel prep. Very affordable as a generic ($10–$30) and widely available, though the large volume can be difficult to drink.
Sutab (Sodium Sulfate/Magnesium Sulfate/Potassium Chloride tablets)
A tablet-based bowel prep with no liquid solution to drink, ideal for patients who struggle with liquid preps. Typically $75–$150.
Clenpiq (Sodium Picosulfate/Magnesium Oxide/Citric Acid)
An ultra-low-volume liquid prep (two 5.4-oz doses) with a cranberry flavor. Well-tolerated but can cost $150–$250.
Plenvu (PEG-3350/Sodium Ascorbate/Sodium Sulfate/Ascorbic Acid)
A low-volume PEG-based prep known for better taste and tolerability. Typically $150–$200.
Prefer Suprep Bowel Prep Kit? We can find it.
Diuretics, ACE inhibitors, ARBs, and NSAIDs
moderateincrease the risk of fluid and electrolyte disturbances
QT-prolonging medications
moderateincreased risk of cardiac arrhythmias when combined with electrolyte changes from Suprep
Seizure-threshold-lowering medications
moderaterisk increases in the setting of electrolyte abnormalities
Oral medications taken within 1 hour of Suprep
moderatemay not be properly absorbed due to the rapid bowel cleansing
Tetracyclines, fluoroquinolones, iron, digoxin, and penicillamine
moderatetake at least 2 hours before and 6 hours after Suprep
Suprep Bowel Prep Kit is a widely used and effective colonoscopy preparation that offers a lower-volume alternative to traditional 4-liter PEG preps. It scores well on our findability scale at 82/100, meaning most patients should be able to fill their prescription without difficulty. While the brand-name version can cost $124–$170 without insurance, generic versions and discount cards can bring the price down to as low as $35. Most insurance plans cover Suprep or its generic, typically with a $10–$50 copay.
If you're having trouble finding Suprep in stock at your local pharmacy, try Medfinder to quickly locate nearby pharmacies that have it available. And if cost is a concern, be sure to ask your pharmacist about the generic version and check for coupons on GoodRx or SingleCare.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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