Comprehensive medication guide to Estazolam including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$10–$40 copay; Tier 2-3 generic, but most Medicare Part D plans do not cover benzodiazepines for insomnia.
Estimated Cash Pricing
$25–$160 retail for 30 tablets; as low as $25–$30 with GoodRx or SingleCare coupons.
Medfinder Findability Score
55/100
Summarize with AI
On this page
Estazolam is a benzodiazepine medication FDA-approved for the short-term treatment of insomnia. It helps people who have difficulty falling asleep or staying asleep. Originally marketed under the brand name ProSom by Abbott Laboratories, the brand has since been discontinued and Estazolam is now available only as a generic. It is typically prescribed for 7–10 days and is taken at bedtime. Patients should plan for a full 7–8 hours of sleep after taking it to avoid next-day drowsiness.
Estazolam belongs to the triazolobenzodiazepine subclass of benzodiazepines. It works by enhancing the effect of , a neurotransmitter that slows brain activity. Estazolam binds to GABA-A receptors, increasing chloride ion flow into neurons, which produces a calming, sedative effect on the central nervous system. This helps reduce the time it takes to fall asleep and can improve sleep duration.
![Why Is Estazolam So Hard to Find? [Explained for 2026]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2F3685b4fdb7a917445042f04cc5bdcfc85cc2bdbc-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
![How to Find a Doctor Who Can Prescribe Estazolam Near You [2026 Guide]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2F64254c34525df5405007daed1339279d0118365e-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
We have a 99% success rate finding medications, even during nationwide shortages.
Need this medication?
1 mg oral tablet — tablet
often used as a starting dose, especially for elderly patients or those sensitive to sedatives
2 mg oral tablet — tablet
the standard dose for most adults with insomnia
Estazolam scores a 55 out of 100 on our findability scale, meaning it can be moderately difficult to locate. While it is not currently listed on the FDA or ASHP drug shortage databases, Estazolam is a low-demand benzodiazepine with only a handful of manufacturers. This limited production volume means individual pharmacies may be out of stock at any given time. If your local pharmacy doesn't have it, try calling independent pharmacies or using Medfinder to check availability near you.
Estazolam can be prescribed by any licensed physician or qualified prescriber, though it is most commonly prescribed by:
Because Estazolam is a Schedule IV controlled substance, prescribers must have a valid DEA registration. Telehealth prescribing of benzodiazepines is generally restricted in most states, so an in-person visit is usually required.
Yes, Estazolam is classified as a Schedule IV controlled substance by the DEA. This means it has a recognized medical use but carries a risk of abuse and physical dependence. The FDA updated its boxed warning for all benzodiazepines in September 2020, highlighting the risks of abuse, misuse, addiction, physical dependence, and potentially life-threatening withdrawal reactions. Estazolam should only be used as directed and for the shortest duration possible.
Serious side effects that require immediate medical attention include complex sleep behaviors (sleepwalking, sleep-driving), severe allergic reactions, respiratory depression (especially if combined with opioids or alcohol), memory impairment, and suicidal thoughts. Do not stop Estazolam abruptly — withdrawal can cause seizures.
Know what you need? Skip the search.
Temazepam (Restoril)
Another benzodiazepine (Schedule IV) FDA-approved for insomnia. Intermediate-acting and more widely available than Estazolam.
Triazolam (Halcion)
A short-acting benzodiazepine (Schedule IV) best suited for sleep-onset difficulty.
Zolpidem (Ambien)
A non-benzodiazepine "Z-drug" (Schedule IV) that targets the same GABA receptors but with more selectivity, potentially fewer side effects.
Suvorexant (Belsomra)
An orexin receptor antagonist (Schedule IV) with a newer mechanism of action and no benzodiazepine-related risks.
Prefer Estazolam? We can find it.
Opioids
moderate(Fentanyl, Oxycodone, Hydrocodone, Morphine, Tramadol) — Combining with benzodiazepines can cause profound sedation, respiratory depression, coma, and death. FDA boxed warning applies.
Alcohol
moderateAdditive CNS depression; avoid completely while taking Estazolam.
Other CNS depressants
moderate(barbiturates, muscle relaxants, sedating antihistamines) — Increased sedation and respiratory risk.
CYP3A4 inhibitors
moderate(Ketoconazole, Clarithromycin, Ritonavir) — May significantly increase Estazolam blood levels.
Sodium Oxybate
moderateContraindicated combination.
Grapefruit juice
moderateMay increase Estazolam levels via CYP3A4 inhibition.
Estazolam is an effective short-term treatment for insomnia, but finding it in stock can be a challenge. With only a few generic manufacturers and no brand-name version available in the U.S., supply can be inconsistent at individual pharmacies. If your pharmacy is out of stock, try checking independent or compounding pharmacies, or use Medfinder to locate it near you. Discount programs like GoodRx and SingleCare can bring the cash price down to as low as $25–$30 for a 30-tablet supply. Talk to your doctor about alternatives like Temazepam or Zolpidem if availability remains an issue.
Medfinder Editorial Standards
Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
ChatGPT
Claude
Perplexity
Grok
Gemini