Clorazepate

How hard is it to find Clorazepate in stock?

Clorazepate is an older, less commonly prescribed benzodiazepine, which means many pharmacies do not routinely stock it. While it is not currently listed on the FDA Drug Shortage Database, limited manufacturer interest and low patient demand can make it difficult to find at your local pharmacy. In 2026, ANI Pharmaceuticals received FDA approval for a new generic version, which may gradually improve supply. If your pharmacy doesn't have it in stock, ask them to order it or try calling independent pharmacies, which may be more willing to special-order niche medications.

Who Can Prescribe Clorazepate?

As a Schedule IV controlled substance, Clorazepate can be prescribed by any licensed physician, nurse practitioner, or physician assistant with DEA prescribing authority. The most common prescribers include:

• Psychiatrists — for anxiety disorders and panic disorder
• Neurologists — for adjunctive seizure management
• Primary Care Physicians (Family Medicine, Internal Medicine) — for anxiety and general management
• Addiction Medicine Specialists — for acute alcohol withdrawal
• Emergency Medicine Physicians — for acute alcohol withdrawal management

Note: Clorazepate is generally not available via telehealth due to DEA regulations on prescribing controlled substances remotely. An in-person visit is typically required.

Is Clorazepate a controlled substance?

Yes. Clorazepate is classified as a DEA Schedule IV controlled substance, meaning it has a recognized medical use but carries a risk of abuse and dependence. All benzodiazepines, including Clorazepate, carry FDA boxed warnings regarding:

• Abuse, misuse, and addiction — which can lead to overdose and death
• Physical dependence and withdrawal — abrupt discontinuation can cause life-threatening seizures
• Concomitant use with opioids — combining benzodiazepines with opioids can result in profound sedation, respiratory depression, coma, and death

Because of these risks, prescriptions may be subject to quantity limits, refill restrictions, and prior authorization requirements by insurance plans.

Common Side Effects of Clorazepate

• Drowsiness
• Dizziness
• Blurred vision
• Dry mouth
• Upset stomach
• Fatigue
• Confusion
• Headache

Serious side effects that require immediate medical attention include respiratory depression (especially when combined with opioids or alcohol), severe sedation, paradoxical reactions (agitation, hostility), seizures from abrupt discontinuation, suicidal thoughts, and signs of allergic reaction.

Final Thoughts on Clorazepate

Clorazepate is an effective but niche benzodiazepine that serves an important role for patients with anxiety, partial seizures, and acute alcohol withdrawal. While it is not in active FDA shortage, its limited manufacturer base and low prescribing volume mean it may not always be readily available at your pharmacy. The good news: generic Clorazepate is affordable, often under $35 for a 30-day supply with a discount coupon, and a new generic manufacturer (ANI Pharmaceuticals) entered the market in 2026. If you're having trouble finding Clorazepate in stock, use Medfinder to locate pharmacies near you that have it available. Don't hesitate to ask your pharmacist to special-order it or to check independent pharmacies, which may be more flexible with niche medications.