Comprehensive medication guide to Benzphetamine including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
With insurance, Benzphetamine copays generally range from $10 to $50, though many plans do not cover weight-loss medications or may require prior authorization.
Estimated Cash Pricing
Without insurance, Benzphetamine typically costs between $70 and $625 for a 90-tablet supply of 50 mg tablets, though discount cards can bring generic prices as low as $11 for a 14-tablet supply.
Medfinder Findability Score
60/100
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Benzphetamine (brand names Didrex and Regimex) is a prescription weight-loss medication classified as a sympathomimetic amine anorectic. It is approved by the FDA as a short-term adjunct to caloric restriction for weight loss in patients with a BMI of 30 or higher who have not responded to diet and exercise alone.
Benzphetamine works by suppressing appetite, making it easier to stick to a reduced-calorie diet. It is intended for use over a period of a few weeks and is typically prescribed alongside a comprehensive weight management plan that includes dietary changes and increased physical activity.
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Benzphetamine is a sympathomimetic amine that stimulates the central nervous system by increasing the release of norepinephrine and dopamine in the brain. These neurotransmitters play key roles in regulating appetite and energy levels. By boosting their activity, Benzphetamine suppresses hunger signals, helping patients eat less.
While pharmacologically similar to amphetamines, Benzphetamine has a lower abuse potential compared to other stimulant-based weight loss medications, which is why it is classified as a Schedule III controlled substance rather than Schedule II.
50 mg oral tablet — tablet
scored, peach-colored, round tablet (immediate-release only)
Benzphetamine has a findability score of 60 out of 100, meaning it can be moderately difficult to locate at your local pharmacy. While Benzphetamine is not currently listed on the FDA drug shortage database, it is an amphetamine derivative subject to DEA production quotas. The broader stimulant medication shortage that began in 2022–2023 has periodically affected availability of all Schedule II–III stimulants, including Benzphetamine.
If your regular pharmacy is out of stock, try calling independent pharmacies in your area or use Medfinder to check real-time availability near you.
Benzphetamine is commonly prescribed by doctors who specialize in weight management, including:
Because Benzphetamine is a controlled substance, it is not currently available through telehealth prescribing services. You will need an in-person visit with a licensed provider.
Yes, Benzphetamine is a Schedule III controlled substance under the Controlled Substances Act. This means it has a moderate potential for physical and psychological dependence, though less than Schedule I or II drugs. As an amphetamine derivative, it is subject to DEA production quotas, which can affect supply availability.
Because of its controlled status, Benzphetamine prescriptions may have limits on refills, and your pharmacy may need to order it specially. Always take Benzphetamine exactly as prescribed and do not share it with others.
Like all medications, Benzphetamine can cause side effects. Common side effects include:
More serious side effects that require immediate medical attention include palpitations, rapid heartbeat, elevated blood pressure, psychotic episodes, and signs of dependence. Contact your doctor right away if you experience any concerning symptoms.
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Phentermine (Adipex-P, Lomaira)
The most commonly prescribed weight-loss stimulant, available as a Schedule IV medication in 15 mg and 37.5 mg tablets
Diethylpropion (Tenuate)
Another sympathomimetic amine approved for short-term weight loss, classified as Schedule IV
Phendimetrazine (Bontril)
A Schedule III medication in the same class as Benzphetamine, available in immediate and extended-release forms
Orlistat (Xenical, Alli)
A non-stimulant option that works by blocking fat absorption; Alli is available over the counter
Prefer Benzphetamine? We can find it.
MAO inhibitors
moderateContraindicated within 14 days due to risk of hypertensive crisis
Other CNS stimulants
moderateIncreased risk of adverse cardiovascular and nervous system effects
Other anorectic agents
majorPotential for serious cardiac problems when combined
Antihypertensives
moderateBenzphetamine may decrease the blood-pressure-lowering effect of these medications
Tricyclic antidepressants
moderateBenzphetamine may enhance the effects of TCAs
Insulin and oral diabetes medications
moderateDosage adjustments may be needed
Acidic foods and beverages
moderateCitrus juices and vitamin C may decrease Benzphetamine absorption
Benzphetamine is a moderately available weight-loss medication with a findability score of 60 out of 100. While not currently in a formal shortage, its status as a DEA-scheduled amphetamine derivative means supply can fluctuate based on production quotas and broader stimulant availability trends.
If your pharmacy is out of stock, don't give up. Try independent pharmacies, ask your pharmacist to check distributor availability, or use Medfinder to locate Benzphetamine in stock near you. With cash prices ranging from $70 to $625 without a discount card, it's also worth checking coupon programs like SingleCare or GoodRx to save on your prescription.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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