Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Amcinonide is a high-potency synthetic topical corticosteroid used to treat inflammatory skin conditions. It is classified as a Class II (ointment) to Class III (cream) corticosteroid on the potency scale, making it one of the stronger options for treating stubborn skin inflammation.
Amcinonide is FDA-approved to treat atopic dermatitis, allergic contact dermatitis, eczema, plaque-type psoriasis, and other corticosteroid-responsive dermatoses. It was originally marketed under the brand name Cyclocort by Lederle Laboratories, though the brand has since been discontinued. Today, only generic versions are available from manufacturers like Taro Pharmaceuticals and Fougera Pharmaceuticals.
Amcinonide is a synthetic fluorinated glucocorticoid that works by suppressing inflammation at the cellular level. When applied to the skin, it reduces the migration of white blood cells (polymorphonuclear leukocytes) to the inflamed area and reverses increased capillary permeability — two key drivers of redness, swelling, and irritation.
At a molecular level, Amcinonide inhibits the enzyme phospholipase A2, which blocks the release of arachidonic acid. This prevents the production of prostaglandins and leukotrienes — inflammatory chemicals responsible for itching, redness, and swelling. The result is reduced inflammation, less itching, and faster healing of affected skin.
All formulations contain the same 0.1% concentration of Amcinonide. The cream is the most commonly dispensed and easiest to find.
Amcinonide is extremely difficult to find at retail pharmacies. With a findability score of just 5 out of 100, this is one of the hardest dermatologic medications to locate. The brand name Cyclocort has been discontinued, and only a handful of generic manufacturers — primarily Taro Pharmaceuticals and Fougera (Sandoz) — still produce it. Limited production volume combined with low market demand means most pharmacies do not stock Amcinonide routinely. The ointment formulation is especially scarce. Patients may need to call multiple pharmacies or use a service like Medfinder to locate it in stock.
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Amcinonide is most commonly prescribed by dermatologists for moderate-to-severe inflammatory skin conditions that haven't responded to lower-potency steroids. However, several other specialties may also prescribe it:
Telehealth consultations are also available for obtaining Amcinonide prescriptions, which can be convenient given the medication's limited in-store availability.
No, Amcinonide is not a controlled substance. It is not scheduled by the DEA and does not have abuse potential. It is a topical anti-inflammatory medication that can be prescribed by any licensed healthcare provider without special restrictions. No ID requirements or prescription monitoring apply.
More serious but rare side effects include HPA axis suppression (with prolonged use or large-area application), secondary skin infections, and vision changes if used near the eyes. Children are particularly susceptible to systemic absorption. Always follow your doctor's instructions regarding duration and area of use.
If you're having trouble finding Amcinonide in stock, several alternative high-potency topical corticosteroids may work for your condition:
Talk to your dermatologist about switching to an alternative if Amcinonide is unavailable. Many patients respond well to other corticosteroids in the same potency range.
Because Amcinonide is a topical medication with minimal systemic absorption, drug interactions are relatively limited compared to oral medications. However, some interactions to be aware of include:
There are no known food interactions with Amcinonide since it is applied topically with minimal systemic absorption. Always inform your doctor of all medications you're using, including other topical products.
Amcinonide is an effective high-potency topical corticosteroid for treating stubborn inflammatory skin conditions like eczema, psoriasis, and contact dermatitis. However, it is one of the most difficult dermatologic medications to find in stock due to limited manufacturers, the discontinuation of the Cyclocort brand, and low production volumes.
If your doctor has prescribed Amcinonide, expect to make several calls to pharmacies or use a tool like Medfinder to track down availability. The cream formulation is your best bet — the ointment and lotion are significantly harder to locate. Discount cards from GoodRx and SingleCare can bring the generic cream price down from over $300 to around $109 for a 60g tube.
If you can't find Amcinonide, ask your prescriber about alternatives like Fluocinonide or Betamethasone Dipropionate, which are more widely available and often less expensive. Your skin condition shouldn't go untreated just because one specific medication is hard to find.
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