Why Is Roszet So Hard to Find?

If you've been prescribed Roszet (Ezetimibe/Rosuvastatin) and can't find it at your pharmacy, you're not alone. Many patients across the country have been struggling to fill their Roszet prescriptions. The short answer: Roszet has been discontinued by its manufacturer, Althera Life Sciences, and is no longer being produced.

In this guide, we'll explain exactly what happened, what your options are, and how to make sure your cholesterol treatment doesn't get interrupted.

What Is Roszet?

Roszet is a prescription medication that combines two cholesterol-lowering drugs in one tablet: Rosuvastatin (a statin) and Ezetimibe (a cholesterol absorption inhibitor). It was approved by the FDA in March 2021 for treating high cholesterol (primary hyperlipidemia) and homozygous familial hypercholesterolemia (HoFH).

The convenience of Roszet was that it combined two medications — which many patients were already taking separately — into a single daily pill. Rosuvastatin works by reducing cholesterol production in the liver, while Ezetimibe blocks cholesterol absorption in the intestines. Together, they provide a powerful dual approach to lowering LDL ("bad") cholesterol.

For more details on how this medication works, see our guide on how Roszet works.

Why Is Roszet So Hard to Find? (3 Key Reasons)

1. The Manufacturer Discontinued All Formulations

The most important reason you can't find Roszet is that Althera Life Sciences discontinued all formulations of the drug. This includes every available strength — from the 10 mg/5 mg tablet all the way up to the 10 mg/40 mg tablet. This is not a temporary shortage; it is a permanent discontinuation.

Once a manufacturer stops producing a medication, existing pharmacy stock runs out quickly. Any remaining supply was likely exhausted by mid-to-late 2025.

2. No Generic Version Is Available

Unlike many other cholesterol medications, there is no generic version of Roszet. The combination of Ezetimibe and Rosuvastatin in a single tablet is protected by patents that aren't expected to expire until around 2033. That means no other company can legally manufacture a generic equivalent.

However, the individual ingredients — generic Rosuvastatin and generic Ezetimibe — are widely available and affordable as separate pills.

3. Limited Insurance Coverage Reduced Demand

Even before the discontinuation, many insurance companies considered Roszet a non-preferred brand. Patients often faced prior authorization requirements or step therapy, meaning they had to try the separate generic components first. This limited commercial success may have contributed to the manufacturer's decision to discontinue the product.

4. FDA Regulatory Issues

The FDA issued an untitled letter to Althera Life Sciences regarding promotional violations for Roszet. While regulatory actions don't directly cause discontinuation, they can add to the business challenges facing a brand-name drug with limited market share.

What You Can Do If You Can't Find Roszet

The good news is that you have several solid options:

• Switch to separate generics: Ask your doctor about taking generic Rosuvastatin and generic Ezetimibe as two separate pills. This provides the exact same active ingredients at a fraction of the cost — often $20 to $55 per month total compared to $150 to $350 for brand Roszet.
• Consider alternative combinations: Vytorin (Ezetimibe/Simvastatin) is another combination cholesterol pill, though it uses a different statin. Generic versions of Vytorin are available.
• Talk to your doctor promptly: Don't skip doses while figuring things out. Your doctor can write a new prescription for the individual components quickly.
• Use Medfinder to check availability: If you want to see whether any pharmacy near you still has remaining Roszet stock, search on Medfinder for real-time availability.

For a full list of alternatives, read our guide on alternatives to Roszet.

How to Save Money on Your Cholesterol Medication

One silver lining of the Roszet discontinuation is that switching to the separate generic components can actually save you hundreds of dollars per month. Generic Rosuvastatin costs as little as $10 to $30 per month, and generic Ezetimibe runs about $10 to $25 per month.

For more tips on cutting costs, check out our guide on how to save money on Roszet and its alternatives.

Final Thoughts

If you've been searching for Roszet with no luck, you now know why: the brand has been permanently discontinued. But this doesn't have to disrupt your cholesterol management. The same active ingredients are available as affordable generics, and your doctor can help you transition smoothly.

Use Medfinder to check pharmacy stock near you or find the best prices on alternative cholesterol medications. And don't wait — keeping your cholesterol treatment on track is important for your long-term heart health.