What Is Sronyx 28 Day?

Sronyx 28 Day is a monophasic combined oral contraceptive (birth control pill) that contains Levonorgestrel 0.1 mg and Ethinyl Estradiol 0.02 mg.

Manufactured by Mayne Pharma, Sronyx belongs to the class of low-dose combined oral contraceptives (COCs). It combines a progestin (Levonorgestrel) with an estrogen (Ethinyl Estradiol) to prevent pregnancy. "Monophasic" means every active pill in the pack contains the same dose of hormones — there's no variation from week to week.

Sronyx is a generic equivalent of Alesse (which has also been discontinued). Other brand names for the same formulation include Lessina, Lutera, Vienva, Aubra, Aviane, Falmina, Larissia, Orsythia, and Delyla.

Important 2026 update: Sronyx has been discontinued by Mayne Pharma. It is no longer being manufactured or distributed. If you're currently taking Sronyx, you'll need to switch to an equivalent generic — the same active ingredients are available under other brand names.

Sronyx is not a controlled substance.

What Is Sronyx 28 Day Used For?

Sronyx is FDA-approved for one indication:

• Prevention of pregnancy

However, doctors also prescribe oral contraceptives like Sronyx off-label for several other conditions:

• Regulation of menstrual cycles: Helps establish predictable periods
• Reduction of menstrual cramps (dysmenorrhea): Many women experience less painful periods on the pill
• Acne management: While not specifically FDA-approved for acne, hormonal contraceptives can improve skin in some women
• Endometriosis symptom management: Continuous or cyclic use can reduce endometriosis-related pain
• Reduction of ovarian cysts: COCs suppress ovulation, which reduces the risk of functional ovarian cysts

How Is Sronyx 28 Day Taken?

Each Sronyx 28 Day pack contains:

• 21 white active tablets — each containing Levonorgestrel 0.1 mg and Ethinyl Estradiol 0.02 mg
• 7 peach inactive (placebo) tablets — no hormones; these help you maintain the daily habit

Here's how to take it:

1. Take one white active tablet daily at the same time each day for 21 days.
2. Then take one peach placebo tablet daily for 7 days. Your period will typically start during this week.
3. Start your next pack immediately after finishing the last placebo tablet — don't skip any days between packs.
4. You can take it with or without food.

Timing matters: Taking your pill at the same time every day maximizes effectiveness and reduces breakthrough bleeding. Many women set a daily phone alarm as a reminder.

If you miss a pill: Take it as soon as you remember. If you miss two or more active pills, use backup contraception (like condoms) for 7 days and consult your pill's patient information leaflet or call your doctor for specific instructions.

Who Should Not Take Sronyx 28 Day?

Sronyx is not safe for everyone. You should not take it if you have:

• Known or suspected pregnancy
• A history of blood clots (deep vein thrombosis or pulmonary embolism)
• History of stroke or cerebrovascular disease
• History of heart attack, angina, or coronary artery disease
• Known or suspected breast cancer or estrogen/progestin-sensitive cancer
• Liver tumors (benign or malignant) or active liver disease
• Undiagnosed abnormal uterine bleeding
• Are a smoker over age 35
• Are taking Hepatitis C drugs containing Ombitasvir/Paritaprevir/Ritonavir (with or without Dasabuvir)

Women with migraines with aura, uncontrolled high blood pressure, or diabetes with vascular complications should also avoid COCs. Your doctor should review your full medical history before prescribing — see our guide on finding a prescriber for what to expect at your appointment.

For details on potential drug interactions, see our dedicated post.

How Much Does Sronyx 28 Day Cost?

Here's what you can expect to pay:

• With insurance: Most plans cover generic oral contraceptives at $0 copay under the ACA contraceptive mandate. Some plans may prefer specific generics (like Aviane over Vienva), so check with your insurer.
• Without insurance (cash price): Equivalent generics typically cost $16–$70 per 28-day pack at retail price.
• With a discount card: GoodRx, SingleCare, and similar programs can bring the price as low as $15.98 per pack.

Since Sronyx is discontinued, there is no active manufacturer savings program. However, the equivalent generics are widely covered and affordable. For a complete breakdown of savings options, see our guide to saving money on Sronyx 28 Day and its equivalents.

For patients who are uninsured or have financial hardship, Planned Parenthood, Title X clinics, and state Medicaid programs often provide oral contraceptives at low or no cost.

Final Thoughts

Sronyx 28 Day is (or was) a straightforward, effective low-dose birth control pill. While the brand itself has been discontinued, the formulation — Levonorgestrel 0.1 mg / Ethinyl Estradiol 0.02 mg — remains widely available under names like Vienva, Aubra, Lutera, and Aviane.

If you're currently on Sronyx and need to switch, the transition is seamless — these are the same active ingredients at the same dose. Talk to your doctor or pharmacist about which equivalent is most readily available and covered by your insurance.

To check where your medication is in stock, visit Medfinder.