What Is Spritam? Uses, Dosage, and What You Need to Know in 2026

Spritam is one of the most technologically unique medications on the market — and yet it's prescribed for one of the oldest neurological conditions: epilepsy. Whether you've just been prescribed Spritam or are doing research for a family member, this guide gives you everything you need to understand what Spritam is, what it does, how to take it, and what to expect.

What Is Spritam?

Spritam is the brand name for levetiracetam tablets for oral suspension. It's an antiepileptic (anti-seizure) medication manufactured by Aprecia Pharmaceuticals and distributed by Prasco Laboratories. What makes Spritam truly extraordinary is how it's made: it was the first FDA-approved prescription drug produced using 3D printing technology.

Using Aprecia's proprietary ZipDose® technology, Spritam is built layer by layer through a process called binder jetting, which bonds powdered medication with a water-based fluid without compression. The result is a highly porous tablet that disintegrates in approximately 11 seconds when placed on the tongue with a sip of liquid. Conventional levetiracetam tablets can take up to 60 seconds to break down. This rapid-dissolve feature is Spritam's defining clinical advantage.

What Is Spritam Approved to Treat?

The FDA has approved Spritam for three specific indications, all involving seizure disorders:

Partial-onset seizures (focal seizures) — in patients 4 years and older weighing more than 20 kg (44 lbs). Spritam can be used alone or as add-on therapy for this indication.

Myoclonic seizures — as add-on therapy for patients 12 years and older with juvenile myoclonic epilepsy (JME). Myoclonic seizures involve brief, shock-like muscle jerks.

Primary generalized tonic-clonic seizures (grand mal) — as add-on therapy for patients 6 years and older with idiopathic generalized epilepsy. These are the classic seizures involving stiffening and rhythmic jerking of the entire body.

Who Is Spritam Designed For?

Spritam's rapid-dissolve formulation addresses a real clinical problem. Many epilepsy patients have difficulty swallowing conventional tablets — either because of neurological conditions affecting swallowing, because they are young children, or because of cognitive or physical impairments. Spritam was specifically designed for:

Patients with dysphagia (difficulty swallowing)

Children who cannot swallow large tablets

Patients who need rapid drug administration (e.g., in seizure-prone situations where speed matters)

Patients with nasogastric (NG) or gastrostomy (G-tube) feeding tubes (Spritam is approved for tube administration)

Available Doses and How to Take Spritam

Spritam is available in four strengths: 250 mg, 500 mg, 750 mg, and 1000 mg. All are round, white to off-white, spearmint-flavored tablets packaged in child-resistant blisters (60 tablets per carton).

There are two ways to take Spritam:

On the tongue: Place the tablet on the tongue and immediately take a sip of liquid. The tablet disintegrates in about 11 seconds and is swallowed with the liquid.

In a cup: Place the tablet in a small amount of liquid, allow it to disperse, then swallow the mixture immediately.

Important: Do not break, cut, or crush Spritam tablets. The 3D-printed structure is integral — altering it destroys the rapid-dissolve property. Spritam must be administered as produced.

Typical Dosing

Spritam is always dosed twice daily. Exact dosing depends on your indication, age, weight, and kidney function. Typical adult starting dose for partial-onset seizures is 500 mg twice daily, which may be increased by 500 mg per dose every 2 weeks up to the recommended dose of 1,500 mg twice daily (3,000 mg/day). Your doctor will tailor your specific dose.

Key Facts at a Glance

Drug class: Pyrrolidine anticonvulsant

FDA approval: August 2015; US market launch March 2016

Controlled substance: No — not DEA scheduled

Available strengths: 250 mg, 500 mg, 750 mg, 1000 mg

Dosing frequency: Twice daily

Cash price (brand): ~$640–$690 per 30-day supply without savings programs

With SPRITAM Serve program: As low as $10/month for commercially insured patients

Generic available: An authorized generic (Levetiracetam Tablets for Oral Suspension by Prasco) is the identical product from the same facility

For more detail, see: How Does Spritam Work? Mechanism of Action Explained and Spritam Side Effects: What to Expect.