What Is Daysee 91 Day? Uses, Dosage, and What You Need to Know in 2026

Daysee 91 Day Is an Extended-Cycle Birth Control Pill That Reduces Your Period to About Four Times a Year

If you've ever wished you could skip most of your periods, Daysee 91 Day was designed for exactly that. It's an extended-cycle oral contraceptive that lets you go about 91 days between periods — meaning roughly four per year instead of twelve.

This guide covers everything you need to know about Daysee 91 Day in 2026: what it is, how it works, how to take it, who should avoid it, and what it costs.

What Is Daysee 91 Day?

Daysee 91 Day is a combination oral contraceptive (birth control pill) that uses an extended-cycle regimen to prevent pregnancy and reduce the number of menstrual periods you have each year.

• Generic name: Levonorgestrel 0.15 mg / Ethinyl Estradiol 0.03 mg (84 tablets) and Ethinyl Estradiol 0.01 mg (7 tablets)
• Drug class: Extended-cycle combination oral contraceptive
• Manufacturer: Lupin Pharmaceuticals, Inc.
• Controlled substance: No — Daysee 91 Day is not a controlled substance and does not require any special prescribing restrictions.
• Generic equivalents: Seasonique (brand-name equivalent), Camrese, Amethia, Ashlyna, Simpesse, Jaimiess, Rivelsa, Fayosim, and Dolishale

Unlike traditional 28-day birth control packs, Daysee comes in a 91-day dispenser. You take 84 active pills containing both hormones, followed by 7 pills with a low dose of estrogen only. Your period comes during those final 7 days — and because you only go through this cycle four times a year, you have far fewer periods.

What Is Daysee 91 Day Used For?

Daysee 91 Day is FDA-approved for one primary indication:

• Prevention of pregnancy in females of reproductive potential

However, doctors also prescribe extended-cycle birth control like Daysee for several off-label uses that benefit from reduced menstrual frequency:

• Menstrual cycle regulation — Provides predictable, quarterly periods for women with irregular cycles
• Reduction of menstrual frequency — Ideal for women who experience debilitating symptoms during menstruation
• Endometriosis symptom management — Fewer periods can mean fewer endometriosis flare-ups and less pelvic pain
• Menstrual migraine prevention — By reducing hormonal fluctuations, extended-cycle pills may help prevent migraines that are triggered by menstruation
• Acne improvement — While not specifically FDA-approved for acne, the hormonal combination in Daysee can improve hormonal acne in some women

How Is Daysee 91 Day Taken?

Taking Daysee 91 Day is straightforward, but the extended cycle means you need to pay attention to the schedule:

The 91-Day Regimen

1. Days 1–84: Take one light blue tablet daily (levonorgestrel 0.15 mg / ethinyl estradiol 0.03 mg). These are your active hormone pills.
2. Days 85–91: Take one mustard tablet daily (ethinyl estradiol 0.01 mg). These are low-dose estrogen pills. Your period will occur during this week.
3. Day 92: Start your next 91-day pack immediately — no gap between packs.

Important Dosing Instructions

• Take it at the same time every day. Consistency is key for effectiveness. Set a daily alarm.
• Begin on the first Sunday after your period starts. If your period starts on Sunday, begin that day.
• Use backup contraception (condoms) for the first 7 days if you're starting Daysee for the first time or switching from another method.
• If you miss a pill: Take it as soon as you remember. If you miss two or more active pills, use backup contraception and refer to the patient information leaflet for specific instructions.
• Take with or without food. If nausea is an issue, taking it with food or at bedtime can help.

Who Should Not Take Daysee 91 Day?

Daysee 91 Day is not appropriate for everyone. Do not take it if you have or have had any of the following:

• You smoke and are over 35 years old — This is the most critical contraindication. Smoking combined with estrogen-containing birth control significantly increases the risk of heart attack, stroke, and blood clots.
• History of blood clots (deep vein thrombosis or pulmonary embolism)
• History of stroke or heart attack
• Known or suspected breast cancer or other estrogen-sensitive cancers
• Liver tumors or active liver disease
• Undiagnosed abnormal uterine bleeding
• Pregnancy — Daysee is not for use during pregnancy
• Hereditary or acquired blood clotting disorders (thrombophilias)
• Uncontrolled high blood pressure
• Diabetes with vascular disease
• Migraine with aura, especially if over 35
• Use of certain hepatitis C medications (ombitasvir/paritaprevir/ritonavir)

Additionally, Daysee 91 Day should not be started until at least 4 weeks after giving birth due to increased blood clot risk. It's not recommended for breastfeeding mothers because it can reduce milk production.

For a full list of drug interactions, see our guide on Daysee 91 Day drug interactions.

How Much Does Daysee 91 Day Cost?

Pricing varies depending on whether you have insurance and whether you fill the brand or generic version:

• Brand-name Daysee: $200–$300 per 91-day pack without insurance
• Generic versions (Camrese, Ashlyna, Amethia, etc.): $27–$60 per 91-day pack with a coupon from GoodRx or SingleCare
• With insurance: Most insurance plans cover extended-cycle oral contraceptives with a $0 copay under the ACA contraceptive mandate. Some plans may require generic substitution.

The generics are therapeutically equivalent and dramatically cheaper. Unless your doctor specifies brand-name Daysee for a medical reason, the generic is almost always the better financial choice.

For detailed savings strategies, see our full guide on how to save money on Daysee 91 Day.

Final Thoughts

Daysee 91 Day is a well-established extended-cycle birth control option that gives you the convenience of only four periods per year. It's been on the market for years, has widely available generics, and is covered by most insurance plans at no cost.

The key things to remember: take it at the same time every day, know the contraindications (especially the smoking/age 35 rule), and don't hesitate to ask your provider about generic options to save money.

Learn more about Daysee 91 Day:

• How Does Daysee 91 Day Work? Mechanism of Action Explained
• Daysee 91 Day Side Effects: What to Expect
• How to Find a Doctor Who Can Prescribe Daysee 91 Day
• How to Check If a Pharmacy Has Daysee 91 Day in Stock