Sprix Is Expensive — But You Have Options

Let's get the sticker shock out of the way: Sprix (Ketorolac nasal spray) costs approximately $3,459 for a 5-day supply without insurance. That's the brand-name price for 5 single-use bottles at most pharmacies.

For a medication you'll use for less than a week, that's a tough pill to swallow — even though it's technically a nasal spray. But before you give up on filling your prescription, read on. There are real ways to bring the cost of Sprix down significantly in 2026.

How Much Does Sprix Cost Without Insurance?

Here's a breakdown of what you might pay at the pharmacy counter without any coverage:

• Brand-name Sprix: ~$3,459 for 5 bottles (one 5-day course)
• Generic Ketorolac tromethamine nasal spray: ~$2,657 with a discount coupon
• Per-day cost: Approximately $530-$690 per day of treatment

For comparison, here's what other forms of the same drug cost:

• Oral Ketorolac tablets (generic, 10 mg): $10-$30 for a 5-day supply
• Injectable Ketorolac (generic Toradol): Under $20 per dose

The price difference between the nasal spray and other Ketorolac forms is dramatic, which is why so many insurance plans push back on covering Sprix.

Coupons and Discount Cards

Prescription discount cards are one of the fastest ways to save on Sprix. These are free to use and don't require insurance. Here are some of the best options:

SingleCare

SingleCare offers coupons that can bring the generic Ketorolac nasal spray down to approximately $2,657 for 5 bottles. That's a savings of about $800 off the retail price. You can print or download the coupon at singlecare.com and present it at most major pharmacies including CVS, Walgreens, Walmart, and Kroger.

GoodRx

GoodRx aggregates prices across pharmacies and often shows similar savings. Check goodrx.com/sprix for current pricing at pharmacies near you. Prices vary by location, so it's worth comparing a few options.

Other Discount Programs

Additional coupon card options include:

• RxSaver — compare prices at nearby pharmacies
• Optum Perks — free coupons accepted at most chains
• BuzzRx — another free discount card with competitive pricing
• America's Pharmacy — may offer savings at independent pharmacies

These cards work even if you have insurance — if your copay is higher than the coupon price, you can use the discount card instead.

Patient Assistance Programs

If you're uninsured or underinsured and struggling to afford Sprix, patient assistance programs (PAPs) may help. These programs provide medications at reduced cost or for free to qualifying patients.

Manufacturer Programs

Assertio Therapeutics (the current manufacturer of Sprix) has offered savings programs for commercially insured patients in the past. Check their website or call their patient support line for current eligibility and savings card availability.

Third-Party Assistance

• NeedyMeds (needymeds.org): A comprehensive database of patient assistance programs, discount drug cards, and state-specific resources. Search for Ketorolac or Sprix.
• RxAssist (rxassist.org): Another database connecting patients to manufacturer and foundation assistance programs.
• RxHope (rxhope.com): Helps patients apply for manufacturer-sponsored PAPs.

Eligibility for these programs typically depends on your income level, insurance status, and residency.

Other Ways to Save on Sprix

Ask for the Generic

If your doctor prescribed brand-name Sprix, ask your pharmacist about generic Ketorolac tromethamine nasal spray. The generic version is bioequivalent (same active ingredient, same dose) and can be $800 or more cheaper than the brand. Make sure your prescription allows generic substitution.

Compare Pharmacy Prices

Prices for the same medication can vary by hundreds of dollars between pharmacies in the same town. Use tools like GoodRx, SingleCare, or Medfinder to compare prices before you fill. Independent pharmacies sometimes offer better prices than chains for specialty medications.

Talk to Your Doctor About Alternatives

If the cost of Sprix is simply out of reach, have an honest conversation with your doctor. Alternatives like oral Ketorolac ($10-$30), injectable Ketorolac (under $20/dose), or other NSAIDs like Diclofenac or Celecoxib ($15-$60/month) may provide effective pain relief at a fraction of the cost. Read more in our alternatives to Sprix guide.

Appeal Insurance Denials

If your insurance denied coverage for Sprix, you have the right to appeal. Steps to take:

1. Ask your doctor to submit a prior authorization with clinical documentation explaining why Sprix is medically necessary
2. Emphasize the non-opioid benefit — many insurers are receptive to opioid-sparing arguments
3. If prior authorization is denied, file a formal appeal through your insurance company's grievance process
4. Contact your state insurance commissioner if you believe the denial is unjustified

Check for Copay Assistance

If your insurance does cover Sprix but the copay is high (common for specialty-tier medications), ask about copay assistance cards from the manufacturer. These can reduce your out-of-pocket cost to as little as $0-$25 per fill for eligible commercially insured patients.

Final Thoughts

Sprix is expensive, but you don't have to pay full retail price. Between discount coupons, generic options, patient assistance programs, and insurance appeals, most patients can find a way to make Sprix more affordable. The key is to explore all your options before giving up.

Start by checking prices with a free coupon card, ask your pharmacist about the generic version, and talk to your doctor if cost is putting your pain management at risk. And if you're having trouble finding Sprix at all, use Medfinder to locate pharmacies with Sprix in stock near you.