Neffy Can Cost $685+ Without Insurance — Here's How to Pay Less

Neffy (Epinephrine nasal spray) is a life-saving medication for people at risk of anaphylaxis. It's also not cheap. Without insurance or savings programs, you could pay $685 to $800 for a 2-pack of Neffy nasal spray devices.

The good news? There are several ways to significantly reduce what you pay — and some patients pay nothing at all. In this guide, we'll break down every option available to help you save money on Neffy in 2026.

What Does Neffy Cost Without Insurance?

Let's start with the numbers:

• Retail cash price: Approximately $685 to $800 for a 2-pack (2 single-dose nasal spray devices)
• Per device: Roughly $340 to $400 each
• No generic available: There is no generic version of Neffy as of 2026, so there's no lower-cost equivalent of the nasal spray specifically

For comparison, here's what alternative epinephrine products cost without insurance:

• EpiPen (brand): $300-$700+ for a 2-pack
• Generic epinephrine auto-injector: $150-$350 for a 2-pack
• Auvi-Q: ~$300 for a 2-pack with coupons

Option 1: Neffy Co-Pay Savings Program (Best for Insured Patients)

If you have commercial health insurance, the Neffy Co-Pay Savings Program from ARS Pharmaceuticals is your best option. Here's what it offers:

• Pay as little as $0 for up to 4 devices (2 packs) per prescription
• Available to patients with commercial insurance (not government-funded plans like Medicare, Medicaid, or Tricare)
• No income requirements — if you have commercial insurance, you're likely eligible

How to enroll:

1. Visit neffy.com/savings-and-support
2. Download and print the savings card
3. Present it at your pharmacy along with your prescription and insurance card

This is one of the most generous copay programs available for any brand-name medication. If you have commercial insurance, start here.

Option 2: Neffy Patient Assistance Program (Best for Uninsured Patients)

If you're uninsured or have no commercial or government drug coverage for Neffy, you may qualify for the Patient Assistance Program (PAP):

• Receive Neffy at no cost if you qualify
• Must have no commercial or government drug coverage for Neffy
• Apply through neffy.com/savings-and-support or call 1-877-MY-NEFFY (877-696-3339)

Patient assistance programs typically require documentation of your financial situation. ARS Pharmaceuticals reviews applications to determine eligibility.

Option 3: Manufacturer Savings for Uninsured Patients

Even if you don't qualify for the full Patient Assistance Program, uninsured patients may still access manufacturer savings:

• Pay as little as $25 per prescription through manufacturer discount programs
• Check neffy.com/savings-and-support for current offers

That's a significant reduction from the $685+ cash price.

Option 4: Prescription Discount Cards and Coupons

Several prescription discount card services offer savings on Neffy:

• GoodRx: Prices starting around $685 with a GoodRx coupon. GoodRx also partners with ARS Pharmaceuticals to offer the lowest discounted cash price at retail pharmacies.
• SingleCare: Check singlecare.com for current pricing
• RxSaver: Compare prices at multiple pharmacies
• Optum Perks: May offer discounts depending on pharmacy

These discount cards are free to use and can be combined with cash pay (not insurance). They're most useful if you don't have insurance or if your insurance doesn't cover Neffy.

Important: Discount cards typically cannot be combined with the manufacturer Co-Pay Savings Program or insurance. Use one or the other.

Option 5: Other Ways to Save

Ask About the Free Virtual Visit Program

ARS Pharmaceuticals offers a free virtual visit program that helps patients get started with Neffy. If you need a prescription and want to try Neffy, this can save you the cost of a doctor visit. Details at neffy.com.

Check Your Insurance Formulary

Before assuming Neffy isn't covered, check your insurance plan's formulary or call the number on your insurance card. If Neffy is covered, your copay could be as low as $0 with the manufacturer savings card on top.

Appeal a Denial

If your insurance denies coverage for Neffy, you have the right to appeal. Ask your doctor to submit a prior authorization with clinical documentation explaining why Neffy is medically necessary for you. Common reasons include needle phobia, inability to self-administer auto-injectors, and pediatric use. See our post on how to find a doctor who can prescribe Neffy for more guidance.

Compare Prices Across Pharmacies

Cash prices for Neffy can vary by pharmacy. Use Medfinder to find pharmacies that have Neffy in stock, then compare prices. Independent pharmacies and certain chains may offer better cash pricing than others.

Look Into FSA/HSA

Neffy is a prescription medication and is eligible for purchase with Flexible Spending Account (FSA) or Health Savings Account (HSA) funds. If you have an FSA or HSA, you can use those pre-tax dollars to pay for Neffy.

Summary: What You'll Pay for Neffy

• With commercial insurance + Co-Pay Savings Program: As little as $0
• Uninsured with Patient Assistance: $0 if eligible
• Uninsured with manufacturer savings: As little as $25
• Cash price with discount card: Starting around $685
• Full retail cash price: $685-$800

Final Thoughts

Neffy is expensive at full price, but very few patients actually need to pay the sticker price. Between the manufacturer's Co-Pay Savings Program, Patient Assistance Program, and prescription discount cards, most patients can get Neffy for $25 or less — and many pay nothing.

Start by checking if you're eligible for the Co-Pay Savings Program at neffy.com/savings-and-support. Then use Medfinder to find a pharmacy near you that has it in stock.

For more information on Neffy, see our guides on what Neffy is, side effects, and alternatives to Neffy.