Iopidine can cost up to $183 without insurance. Learn how to save with coupons, discount cards, and patient assistance programs in 2026.
If you've been prescribed Iopidine (Apraclonidine) eye drops and are worried about the cost, you're not alone. Without insurance, this medication can run anywhere from $86 to $183 for a single bottle. But there are several ways to bring that price down significantly — in some cases to as little as $13.
In this guide, we'll break down the cost of Iopidine with and without insurance, walk you through the best coupons and discount cards, explain patient assistance programs, and share other ways to save.
The price of Iopidine depends on whether you're buying brand-name or generic, and which formulation you need:
These prices are what you'd pay out of pocket at a typical retail pharmacy without any insurance or discount card. The good news is that you rarely need to pay full retail price — there are several ways to save.
The single easiest way to save money on Iopidine is to make sure you're getting generic Apraclonidine instead of brand-name Iopidine. The generic contains the exact same active ingredient (Apraclonidine hydrochloride) at the same concentration and is FDA-approved as therapeutically equivalent.
If your prescription is written for "Iopidine," your pharmacist can usually substitute the generic automatically unless your doctor has written "dispense as written" (DAW). If you're unsure, ask your pharmacist or call your doctor's office to confirm that generic substitution is acceptable.
Switching from brand to generic alone can save you $50 or more per bottle.
Prescription discount cards and coupons can dramatically reduce the price of generic Apraclonidine. These are free to use and work even if you don't have insurance — or if your insurance copay is higher than the coupon price.
Here are the best options for Iopidine/Apraclonidine in 2026:
GoodRx offers some of the lowest prices for generic Apraclonidine. As of recent pricing data, you can get a 5 mL bottle of Apraclonidine 0.5% for as low as $13-$15 with a free GoodRx coupon. Prices vary by pharmacy, so compare several locations on the GoodRx website or app.
SingleCare offers generic Apraclonidine for around $68 for a 5 mL bottle. While higher than GoodRx in some cases, SingleCare may offer better prices at certain pharmacies. It's worth checking both.
RxSaver compares prices across multiple discount programs and can help you find the best deal at pharmacies near you. Check rxsaver.com for current Apraclonidine pricing.
Several other free discount cards may offer savings on Apraclonidine:
These cards are free, require no sign-up fee or insurance, and can be used at most major pharmacies. Simply present the coupon at the pharmacy counter when filling your prescription.
Important: Discount coupons cannot be combined with insurance. Use whichever option gives you the lower price — your insurance copay or the coupon price.
If you're uninsured or underinsured and the cost of Iopidine is a significant financial burden, patient assistance programs (PAPs) may be able to help.
Alcon Laboratories, the manufacturer of Iopidine, offers the Alcon Cares Patient Assistance Program. This program may provide Alcon medications at no cost to eligible patients who:
Your doctor's office will need to initiate the application. Visit the Alcon website or contact their patient assistance department for details and eligibility requirements.
NeedyMeds is a nonprofit organization that maintains a database of patient assistance programs, discount drug cards, and other cost-saving resources. Search for "Apraclonidine" or "Iopidine" on their website to see if additional programs are available.
RxAssist is another comprehensive database of patient assistance programs. It can help you identify manufacturer programs, state programs, and nonprofit assistance that may cover your medication costs.
Prices for the same medication can vary widely between pharmacies — sometimes by $50 or more. Use Medfinder to find Iopidine in stock, and then compare prices using GoodRx or SingleCare before choosing where to fill your prescription.
If you're using Apraclonidine for more than a short course, ask your pharmacist or insurance plan about 90-day supply pricing. Some plans offer lower per-unit costs for larger quantities, and mail-order pharmacies may provide additional savings.
If you have health insurance, check whether Apraclonidine is on your plan's formulary (list of covered drugs). Generic Apraclonidine is covered by most insurance plans, though you may need to meet your deductible first. If brand-name Iopidine is not covered, generic should be — ask your pharmacist to fill with the generic.
Some states offer pharmaceutical assistance programs (SPAPs) for residents who meet certain income criteria. These programs can supplement Medicare or Medicaid coverage and may help cover the cost of Apraclonidine. Check with your state's health department or visit NeedyMeds for a list of state programs.
Iopidine doesn't have to break the bank. By switching to generic Apraclonidine and using a free discount coupon, most patients can bring the cost down from $128+ to as little as $13-$15 per bottle. For those with financial hardship, patient assistance programs like Alcon Cares can provide medication at no cost.
Start by checking prices on GoodRx and SingleCare, and use Medfinder to find a pharmacy that has Apraclonidine in stock near you. For more about this medication, see our guides on what Iopidine is, Iopidine side effects, and drug interactions to know about.
You focus on staying healthy. We'll handle the rest.
Try Medfinder Concierge FreeMedfinder's mission is to ensure every patient gets access to the medications they need. We believe this begins with trustworthy information. Our core values guide everything we do, including the standards that shape the accuracy, transparency, and quality of our content. We’re committed to delivering information that’s evidence-based, regularly updated, and easy to understand. For more details on our editorial process, see here.
%2C%20Color%3DOriginal.png)
