Everolimus can cost over $20,000/month without insurance. Learn how to save with generics, copay cards, patient assistance programs, and more in 2026.
Let's be upfront: Everolimus is one of the most expensive medications on the market. Brand-name Afinitor can cost $15,000 to $22,000 per month without insurance. Even with insurance, specialty tier copays can leave you paying $1,000 to $3,000 out of pocket per month.
That's a staggering amount of money, especially when you're already dealing with a serious health condition. But there are real ways to bring your costs down — sometimes dramatically. In this guide, we'll walk you through every option available in 2026.
Here's what you'd pay at a pharmacy without any insurance or discounts:
The price difference between brand and generic is enormous — which is why switching to generic is often the single biggest money-saver.
If you're currently taking brand-name Afinitor and your doctor approves, switching to generic Everolimus could save you thousands of dollars per month. Generic versions contain the same active ingredient and are rated therapeutically equivalent by the FDA.
Generic Everolimus is available in multiple strengths from several manufacturers. Ask your doctor and pharmacist about making the switch. In many cases, your insurance plan may actually require the generic version.
Even if you don't have insurance, generic Everolimus at $500–$3,000/month is dramatically less than $15,000–$22,000/month for brand-name Afinitor.
Prescription discount cards can help reduce the cost of generic Everolimus at many pharmacies. These cards are free and don't require insurance. Some options to check:
Keep in mind that discount cards typically work best for generic medications. Brand-name Afinitor is so expensive that discount cards may not make a significant dent. For brand-name savings, manufacturer programs (below) are usually more effective.
Important: Prescription discount cards cannot be combined with insurance. Use whichever gives you the lower price.
Novartis, the maker of Afinitor and Zortress, offers a copay assistance program for patients with commercial (private) insurance. Key details:
This program can save commercially insured patients $10,000 or more per year. If you have private insurance and you're not enrolled, you're likely overpaying.
If you're uninsured or underinsured, you may qualify for free Everolimus through a patient assistance program:
Novartis provides Afinitor and Zortress at no cost to patients who:
Your doctor's office can help you apply, or you can contact Novartis directly.
Several independent foundations help patients with copay costs, even those on Medicare:
Note for Medicare patients: The Novartis copay card cannot be used with Medicare, but these independent foundations often can help cover Medicare Part D copays. Check each foundation's current fund availability, as some open and close enrollment based on funding.
Some specialty pharmacies and insurance plans offer lower per-month costs when you fill a 90-day supply instead of 30 days. Ask your pharmacy if this option is available for Everolimus.
Not all specialty pharmacies charge the same price. If you're paying out of pocket for generic Everolimus, call 2–3 specialty pharmacies to compare prices. Use Medfinder to find pharmacies that stock it.
Some states offer their own pharmaceutical assistance programs for residents with high medication costs. These programs vary by state and may cover part of your Everolimus costs.
If you're taking Everolimus for cancer, ask your oncologist about clinical trials. Patients enrolled in trials often receive the study medication at no cost, along with additional monitoring and care.
Many cancer centers and transplant programs have social workers or financial counselors who specialize in helping patients access medications. They know the landscape of assistance programs and can help you apply.
The difference between doing nothing and using available resources could be tens of thousands of dollars per year.
No one should have to choose between their health and their finances. Everolimus is expensive, but there are real, meaningful ways to reduce what you pay — from switching to generic to enrolling in manufacturer and foundation assistance programs.
Start by talking to your doctor, your specialty pharmacy, and any financial counselors available through your treatment center. Use tools like Medfinder to find the medication in stock and compare options.
For more information about Everolimus, explore our other guides:
You focus on staying healthy. We'll handle the rest.
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