Learn how to save money on Entyvio in 2026. Covers cash prices, copay cards, patient assistance programs, and tips to reduce your out-of-pocket costs.
Entyvio (Vedolizumab) is one of the most effective treatments for moderate to severe ulcerative colitis and Crohn's disease. It's also one of the most expensive. With a cash price approaching $10,000 per IV infusion and $3,500 per subcutaneous pen, the cost of Entyvio without insurance can be overwhelming.
But here's what many patients don't realize: there are multiple programs and strategies that can dramatically reduce — or even eliminate — your out-of-pocket costs. In this guide, we'll walk you through every option available in 2026 to help you save money on Entyvio.
Let's start with the numbers so you know what you're working with:
The total annual cost depends on your formulation and dosing schedule:
These are staggering numbers. But very few patients actually pay anything close to these amounts. Here's how to bring your costs down.
The single most important resource for Entyvio patients is EntyvioConnect, Takeda's official patient support program.
If you have commercial (private) health insurance, you may be eligible to pay as little as $0 per dose through the EntyvioConnect copay card. The program covers both IV infusions and SC injections up to a maximum annual benefit amount.
To enroll:
Who qualifies: Patients with commercial insurance (employer plans, marketplace plans, individual plans). The FEHB (Federal Employees Health Benefit) program is also eligible.
Who does NOT qualify: Patients on Medicare, Medicaid, TRICARE, VA, or other government-funded healthcare programs cannot use the copay card.
If you don't have insurance or your insurance doesn't cover Entyvio, Takeda's Patient Assistance Program may provide Entyvio at no cost. This is a separate program from the copay card and is based on financial need.
To apply:
If you don't qualify for EntyvioConnect or need additional savings, several coupon and discount card programs may help:
GoodRx occasionally lists coupons for Entyvio, though discounts on specialty biologics are generally modest compared to generic medications. It's worth checking GoodRx for current pricing at specialty pharmacies in your area.
SingleCare may offer discounts on the Entyvio Pen through participating specialty pharmacies. Savings vary by location and pharmacy.
Sites like RxSaver, Optum Perks, and BuzzRx aggregate pricing across pharmacies. While savings on specialty biologics are often limited, checking multiple sources can occasionally reveal a better price — especially for the SC formulation.
Important note: Coupon cards and discount programs typically cannot be combined with government insurance (Medicare, Medicaid) or with each other. Always check the terms.
If you don't qualify for Takeda's program, other organizations may be able to help:
The PAN Foundation provides financial assistance for underinsured patients. They periodically open disease-specific funds, including for inflammatory bowel disease. Grants can help cover copays, coinsurance, and deductibles.
Check: panfoundation.org
Similar to PAN, the HealthWell Foundation offers grants for patients who have insurance but face high out-of-pocket costs. IBD funds may be available depending on the time of year.
The Crohn's & Colitis Foundation offers resources and referrals to financial assistance programs for IBD patients. They maintain an updated list of available programs on their website.
Both NeedyMeds.org and RxAssist.org maintain comprehensive databases of patient assistance programs, copay cards, and discount opportunities for hundreds of medications, including Entyvio.
Depending on your insurance plan's structure, one formulation may be significantly cheaper for you than the other:
Ask your insurance company to compare your estimated costs for each formulation. Your doctor can help you understand whether switching is clinically appropriate.
If you're on Medicare:
Some states offer pharmaceutical assistance programs (SPAPs) that can supplement your federal coverage. Check with your state's health department or visit Medicare.gov for a list of programs in your state.
Entyvio is expensive at list price, but very few patients should pay full price. Between Takeda's EntyvioConnect program, independent foundations, insurance optimization, and discount tools, there are multiple layers of savings available.
The key is to start early. Don't wait until you get a surprise bill to explore your options. Enroll in EntyvioConnect when you first start treatment, understand your insurance benefits, and keep a list of backup assistance programs in case your situation changes.
For help finding Entyvio in stock at an affordable price, visit Medfinder.
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You focus on staying healthy. We'll handle the rest.
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